Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 1001, Issue , 2015, Pages 202-211

  Ma, Yong ^a   Gao, Song ^a   Hu, Ming ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

Celecoxib; Drug distribution; Metabolites; Pharmacokinetics; UPLC MS MS

Indexed keywords

BIOMOLECULES; CELLS; EXTRACTION; LIQUID CHROMATOGRAPHY; METABOLITES; PHARMACOKINETICS; RATS;

CELECOXIB; DISTRIBUTION PATTERNS; DRUG DISTRIBUTION; LINEAR RESPONSE RANGE; LIQUID-LIQUID EXTRACTION; MULTIPLE REACTIONS MONITORING; PHARMACOKINETIC STUDIES; UPLC-MS/MS;

BLOOD;

CARBOXYCELECOXIB; CARBOXYCELECOXIB GLUCURONIDE; CELECOXIB; DRUG METABOLITE; HYDROXYCELECOXIB; HYDROXYCELECOXIB GLUCURONIDE; UNCLASSIFIED DRUG; CYCLOOXYGENASE 2 INHIBITOR;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD; BLOOD CELL; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; HYDROLYSIS; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETER; MASS SPECTROMETRY; METABOLITE; MULTIPLE REACTIONS MONITORING; NONHUMAN; PHARMACOKINETICS; PLASMA; PRIORITY JOURNAL; PROCEDURES; RADIOACTIVITY; RAT; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; LIQUID CHROMATOGRAPHY; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

RATTUS;

ANIMALS; CELECOXIB; CHROMATOGRAPHY, LIQUID; CYCLOOXYGENASE 2 INHIBITORS; MALE; RATS; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY;

EID: 84939551830     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2015.07.026     Document Type: Article

References (55)

1. Dubois R.N., Abramson S.B., Crofford L., Gupta R.A., Simon L.S., Van De Putte L.B.A., Lipsky P.E. FASEB J. 1998, 12:1063.
2. Smyth E.M., Grosser T., Wang M., Yu Y., FitzGerald G.A. J. Lipid Res. 2009, 50:S423.
3. Turini M.E., DuBois R.N. Ann. Rev. Med. 2002, 53:35.
4. Hla T., Bishop-Bailey D., Liu C.H., Schaefers H.J., Trifan O.C. Int. J. Biochem. Cell Biol. 1999, 31:551.
5. Vane J.R., Bakhle Y.S., Botting R.M. Ann. Rev. Pharmacol. Toxicol. 1998, 38:97.
6. Hida T., Yatabe Y., Achiwa H., Muramatsu H., Kozaki K.-I., Nakamura S., Ogawa M., Mitsudomi T., Sugiura T., Takahashi T. Cancer Res. 1998, 58:3761.
7. Masferrer J.L., Zweifel B.S., Manning P.T., Hauser S.D., Leahy K.M., Smith W.G., Isakson P.C., Seibert K. Proc. Natl. Acad. Sci. 1994, 91:3228.
8. Seibert K., Zhang Y., Leahy K., Hauser S., Masferrer J., Perkins W., Lee L., Isakson P. Proc. Natl. Acad. Sci. 1994, 91:12013.
9. Meade E.A., Smith W.L., DeWitt D.L. J. Biol. Chem. 1993, 268:6610.
10. Wallace J.L., McKnight W., Reuter B.K., Vergnolle N. Gastroenterology 2000, 119:706.
11. Bombardier C., Laine L., Reicin A., Shapiro D., Burgos-Vargas R., Davis B., Day R., Ferraz M.B., Hawkey C.J., Hochberg M.C., Kvien T.K., Schnitzer T.J. N. Engl. J. Med. 2000, 343:1520.
12. Chan F.K.L., Hung L.C.T., Suen B.Y., Wu J.C.Y., Lee K.C., Leung V.K.S., Hui A.J., To K.F., Leung W.K., Wong V.W.S., Chung S.C.S., Sung J.J.Y. N. Engl. J. Med. 2002, 347:2104.
13. Williams C.S., Mann M., DuBois R.N. Oncogene 1999, 18:7908.
14. Greenhough A., Smartt H.J.M., Moore A.E., Roberts H.R., Williams A.C., Paraskeva C., Kaidi A. Carcinogenesis 2009, 30:377.
15. Harris R.E. Inflammopharmacology 2009, 17:55.
16. Bertagnolli M.M., Eagle C.J., Zauber A.G., Redston M., Solomon S.D., Kim K., Tang J., Rosenstein R.B., Wittes J., Corle D., Hess T.M., Woloj G.M., Boisserie F., Anderson W.F., Viner J.L., Bagheri D., Burn J., Chung D.C., Dewar T., Foley T.R., Hoffman N., Macrae F., Pruitt R.E., Saltzman J.R., Salzberg B., Sylwestrowicz T., Gordon G.B., Hawk E.T. N. Engl. J. Med. 2006, 355:873.
17. Baron J.A., Sandler R.S., Bresalier R.S., Quan H., Riddell R., Lanas A., Bolognese J.A., Oxenius B., Horgan K., Loftus S., Morton D.G. Gastroenterology 2006, 131:1674.
18. Bresalier R.S., Sandler R.S., Quan H., Bolognese J.A., Oxenius B., Horgan K., Lines C., Riddell R., Morton D., Lanas A., Konstam M.A., Baron J.A. N. Engl. J. Med. 2005, 352:1092.
19. Jendrossek V. Cancer Lett. 2013, 332:313.
20. Kismet K., Akay M.T., Abbasoğlu O., Ercan A. Cancer Detect. Prev. 2004, 28:127.
21. Solomon S.D., Wittes J., Finn P.V., Fowler R., Viner J., Bertagnolli M.M., Arber N., Levin B., Meinert C.L., Martin B., Pater J.L., Goss P.E., Lance P., Obara S., Chew E.Y., Kim J., Arndt G., Hawk E., Group F.T.C.T.S.A. Circulation 2008, 117:2104.
22. Davies N., McLachlan A., Day R., Williams K. Clin. Pharmacokinet. 2000, 38:225.
23. Paulson S.K., Hribar J.D., Liu N.W.K., Hajdu E., Bible R.H., Piergies A., Karim A. Drug Metab. Dispos. 2000, 28:308.
24. Paulson S.K., Zhang J.Y., Breau A.P., Hribar J.D., Liu N.W.K., Jessen S.M., Lawal Y.M., Cogburn J.N., Gresk C.J., Markos C.S., Maziasz T.J., Schoenhard G.L., Burton E.G. Drug Metab. Dispos. 2000, 28:514.
25. Sandberg M., Yasar Ü., Strömberg P., Höög J.-O., Eliasson E. Br. J. Clin. Pharmacol. 2002, 54:423.
26. Tang C., Shou M., Mei Q., Rushmore T.H., Rodrigues A.D. J. Pharmacol. Exp. Ther. 2000, 293:453.
27. Bailey M.J., Dickinson R.G. Chem. Biol. Interact. 2003, 145:117.
28. Dickinson R.G., Hooper W.D., Eadie M.J. Drug Metab. Dispos. 1984, 12:247.
29. Penning T.D., Talley J.J., Bertenshaw S.R., Carter J.S., Collins P.W., Docter S., Graneto M.J., Lee L.F., Malecha J.W., Miyashiro J.M., Rogers R.S., Rogier D.J., Yu S.S., Anderson G.D., Burton E.G., Cogburn J.N., Gregory S.A., Koboldt C.M., Perkins W.E., Seibert K., Veenhuizen A.W., Zhang Y.Y., Isakson P.C. J. Med. Chem. 1997, 40:1347.
30. Rose M.J., Woolf E.J., Matuszewski B.K. J. Chromatogr. B: Biomed. Sci. Appl. 2000, 738:377.
31. Schönberger F., Heinkele G., Mürdter T.E., Brenner S., Klotz U., Hofmann U. J. Chromatogr. B 2002, 768:255.
32. Zarghi A., Shafaati A., Foroutan S.M., Khoddam A. J. Chromatogr. B 2006, 835:100.
33. Bräutigam L., Vetter G., Tegeder I., Heinkele G., Geisslinger G. J. Chromatogr. B: Biomed. Sci. Appl. 2001, 761:203.
34. Ho E.N.M., Leung D.K.K., Wan T.S.M., Yu N.H. J. Chromatogr. A 2006, 1120:38.
35. Thappali S.R., Varanasi K., Veeraraghavan S., Arla R., Chennupati S., Rajamanickam M., Vakkalanka S., Khagga M. Sci. Pharm. 2012, 80:633.
36. Park M.-S., Shim W.-S., Yim S.-V., Lee K.-T. J. Chromatogr. B 2012, 902:137.
37. Zhang J.Y., Wang Y., Dudkowski C., Yang D.-C., Chang M., Yuan J., Paulson S.K., Breau A.P. J. Mass Spectrom. 2000, 35:1259.
38. Mamidi R.N.V.S., Mullangi R., Kota J., Bhamidipati R., Khan A.A., Katneni K., Datla S., Singh S.K., Rao K.Y., Seshagiri Rao C., Srinivas N.R., Rajagopalan R. Biopharm. Drug Dispos. 2002, 23:273.
39. FitzGerald G.A. N. Engl. J. Med. 2004, 351:1709.
40. Chen J., Lin H., Hu M. J. Pharmacol. Exp. Ther. 2003, 304:1228.
41. Uddin M.J., Crews B.C., Ghebreselasie K., Marnett L.J. Bioconjugate Chem. 2013, 24:712.
42. Zhou Q., Zheng Z., Xia B., Tang L., Lv C., Liu W., Liu Z., Hu M. Pharm. Res. 2010, 27:1568.
43. Tang L., Singh R., Liu Z., Hu M. Mol. Pharm. 2009, 6:1466.
44. Yang Z., Zhu W., Gao S., Xu H., Wu B., Kulkarni K., Singh R., Tang L., Hu M. J. Pharm. Biomed. Anal. 2010, 53:81.
45. Kole P.L., Venkatesh G., Kotecha J., Sheshala R. Biomed. Chromatogr. 2011, 25:199.
46. Sutera S.P., Chang K., Marvel J., Williamson J.R. Am. J. Physiol. Heart. Circ. Physiol. 1992, 263:H945.
47. Abdel-Hamid M., Novotny L., Hamza H. J. Chromatogr. B: Biomed. Sci. Appl. 2001, 753:401.
48. Störmer E., Bauer S., Kirchheiner J., Brockmöller J., Roots I. J. Chromatogr. B 2003, 783:207.
49. Miles K.K., Stern S.T., Smith P.C., Kessler F.K., Ali S., Ritter J.K. Drug Metab. Dispos. 2005, 33:1513.
50. Soars M.G., Riley R.J., Findlay K.A.B., Coffey M.J., Burchell B. Drug Metab. Dispos. 2001, 29:121.
51. Kuo C., Hanioka N., Hoshikawa Y., Oguri K., Yoshimura H. J. Pharmacobiodyn. 1991, 14:187.
52. Hinderling P.H. Pharmacol. Rev. 1997, 49:279.
53. Capone M.L., Tacconelli S., Di Francesco L., Sacchetti A., Sciulli M.G., Patrignani P. Prostaglandins Other Lipid Mediators 2007, 82:85.
54. Solomon S.D., McMurray J.J.V., Pfeffer M.A., Wittes J., Fowler R., Finn P., Anderson W.F., Zauber A., Hawk E., Bertagnolli M. N. Engl. J. Med. 2005, 352:1071.
55. Solomon S.D., Pfeffer M.A., McMurray J.J.V., Fowler R., Finn P., Levin B., Eagle C., Hawk E., Lechuga M., Zauber A.G., Bertagnolli M.M., Arber N., Wittes J., f.t A.P.C., Investigators P.T. Circulation 2006, 114:1028.