Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype

DMM Disease Models and Mechanisms

Volumn 8, Issue 8, 2015, Pages 999-1009

  Fajardo, Val A ^a   Bombardier, Eric ^a   McMillan, Elliott ^a   Tran, Khanh ^a   Wadsworth, Brennan J ^a   Gamu, Daniel ^a   Hopf, Andrew ^a   Vigna, Chris ^a   Smith, Ian C ^a   Bellissimo, Catherine ^a   Michel, Robin N ^b   Tarnopolsky, Mark A ^c   Quadrilatero, Joe ^a   Tupling, A Russell ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b Dept of Electrical and Computer Engineering   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Calcium regulation; Congenital myopathy; Dynamin 2; SERCA; Skeletal muscle

Indexed keywords

DYNAMIN II; MICRORNA; PHOSPHOLAMBAN; REACTIVE OXYGEN METABOLITE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; CALCIUM; CALCIUM BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL AGGREGATION; CENTRONUCLEAR MYOPATHY; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; GLUTEUS MINIMUS MUSCLE; HISTOPATHOLOGY; HOMOGENATE; HUMAN; HUMAN TISSUE; HYPOTROPHY; MOUSE; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE WEAKNESS; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SKELETAL MUSCLE; SOLEUS MUSCLE; TREADMILL EXERCISE; UPREGULATION; WESTERN BLOTTING; ADOLESCENT; ADULT; ANIMAL; ANIMAL MUSCULAR DYSTROPHY; DRUG EFFECTS; ENZYMOLOGY; FIBROSIS; MALE; METABOLISM; MUSCLE; MYOPATHY; PATHOLOGY;

MURINAE; MUS;

ADOLESCENT; ADULT; ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; DYNAMIN II; FIBROSIS; HUMANS; MALE; MICE; MUSCLES; MUSCULAR ATROPHY; MUSCULAR DYSTROPHY, ANIMAL; MYOPATHIES, STRUCTURAL, CONGENITAL; OXIDATIVE STRESS; PHENOTYPE; PROTEOLYSIS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES;

EID: 84939551519     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.020859     Document Type: Article

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