-
1
-
-
33750466230
-
Introduction to NF-κB: Players, pathways, perspectives
-
Gilmore, T. D. (2006) Introduction to NF-κB: players, pathways, perspectives. Oncogene 25, 6680-6684
-
(2006)
Oncogene
, vol.25
, pp. 6680-6684
-
-
Gilmore, T.D.1
-
2
-
-
33750457370
-
Post-translational modifications regulating the activity and function of the nuclear factor κB pathway
-
Perkins, N. D. (2006) Post-translational modifications regulating the activity and function of the nuclear factor κB pathway. Oncogene 25, 6717-6730
-
(2006)
Oncogene
, vol.25
, pp. 6717-6730
-
-
Perkins, N.D.1
-
3
-
-
11844269840
-
Phosphorylation of NF-κB and IκB proteins: Implications in cancer and inflammation
-
Viatour, P., Merville, M. P., Bours, V., and Chariot, A. (2005) Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammation. Trends Biochem. Sci. 30, 43-52
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 43-52
-
-
Viatour, P.1
Merville, M.P.2
Bours, V.3
Chariot, A.4
-
4
-
-
23144449789
-
Ubiquitin signalling in the NF-κB pathway
-
Chen, Z. J. (2005) Ubiquitin signalling in the NF-κB pathway. Nat. Cell Biol. 7, 758-765
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
5
-
-
0141594607
-
Regulation of distinct biological activities of the NF-κB transcription factor complex by acetylation
-
Chen, L. F., and Greene, W. C. (2003) Regulation of distinct biological activities of the NF-κB transcription factor complex by acetylation. J. Mol. Med. 81, 549-557
-
(2003)
J. Mol. Med.
, vol.81
, pp. 549-557
-
-
Chen, L.F.1
Greene, W.C.2
-
6
-
-
33646575937
-
Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-κB activation
-
Nasr, R., Chiari, E., El-Sabban, M., Mahieux, R., Kfoury, Y., Abdulhay, M., Yazbeck, V., Hermine, O., de Thé, H., Pique, C., and Bazarbachi, A. (2006) Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-κB activation. Blood 107, 4021-4029
-
(2006)
Blood
, vol.107
, pp. 4021-4029
-
-
Nasr, R.1
Chiari, E.2
El-Sabban, M.3
Mahieux, R.4
Kfoury, Y.5
Abdulhay, M.6
Yazbeck, V.7
Hermine, O.8
De Thé, H.9
Pique, C.10
Bazarbachi, A.11
-
7
-
-
0035852845
-
Inhibition of NF-κB by S-nitrosylation
-
Marshall, H. E., and Stamler, J. S. (2001) Inhibition of NF-κB by S-nitrosylation. Biochemistry 40, 1688-1693
-
(2001)
Biochemistry
, vol.40
, pp. 1688-1693
-
-
Marshall, H.E.1
Stamler, J.S.2
-
8
-
-
84882309904
-
PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB
-
Wei, H., Wang, B., Miyagi, M., She, Y., Gopalan, B., Huang, D. B., Ghosh, G., Stark, G. R., and Lu, T. (2013) PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB. Proc. Natl. Acad. Sci. U.S.A. 110, 13516-13521
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 13516-13521
-
-
Wei, H.1
Wang, B.2
Miyagi, M.3
She, Y.4
Gopalan, B.5
Huang, D.B.6
Ghosh, G.7
Stark, G.R.8
Lu, T.9
-
9
-
-
70349330577
-
The regulation of protein phosphorylation
-
Johnson, L. N. (2009) The regulation of protein phosphorylation. Biochem. Soc. Trans. 37, 627-641
-
(2009)
Biochem. Soc. Trans.
, vol.37
, pp. 627-641
-
-
Johnson, L.N.1
-
10
-
-
0030012189
-
Estrogenregulatesactivityofcyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells
-
Foster,J.S.,andWimalasena,J.(1996)Estrogenregulatesactivityofcyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells. Mol. Endocrinol. 10, 488-498
-
(1996)
Mol. Endocrinol.
, vol.10
, pp. 488-498
-
-
Foster, J.S.1
Wimalasena, J.2
-
11
-
-
0034797512
-
The role of protein phosphorylation in human health and disease: The Sir Hans Krebs Medal Lecture
-
Cohen, P. (2001) The role of protein phosphorylation in human health and disease: The Sir Hans Krebs Medal Lecture. Eur. J. Biochem. 268, 5001-5010
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 5001-5010
-
-
Cohen, P.1
-
12
-
-
84862003013
-
Phosphorylation of p65(RelA) on Ser-547 by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress
-
Sabatel, H., Di Valentin, E., Gloire, G., Dequiedt, F., Piette, J., and Habraken, Y. (2012) Phosphorylation of p65(RelA) on Ser-547 by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress. PLoS ONE 7, e38246
-
(2012)
PLoS ONE
, vol.7
-
-
Sabatel, H.1
Di Valentin, E.2
Gloire, G.3
Dequiedt, F.4
Piette, J.5
Habraken, Y.6
-
13
-
-
84872078365
-
Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-κB and RNA polymerase II promoter recruitment
-
Hochrainer, K., Racchumi, G., and Anrather, J. (2013) Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-κB and RNA polymerase II promoter recruitment. J. Biol. Chem. 288, 285-293
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 285-293
-
-
Hochrainer, K.1
Racchumi, G.2
Anrather, J.3
-
14
-
-
0030991201
-
The transcriptional activity of NF-κB is regulated by the IκB-associated PKAc subunit through a cyclic AMP-independent mechanism
-
Zhong, H., SuYang, H., Erdjument-Bromage, H., Tempst, P., and Ghosh, S. (1997) The transcriptional activity of NF-κB is regulated by the IκB-associated PKAc subunit through a cyclic AMP-independent mechanism. Cell 89, 413-424
-
(1997)
Cell
, vol.89
, pp. 413-424
-
-
Zhong, H.1
SuYang, H.2
Erdjument-Bromage, H.3
Tempst, P.4
Ghosh, S.5
-
15
-
-
0032039076
-
Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
-
Zhong, H., Voll, R. E., and Ghosh, S. (1998) Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell 1, 661-671
-
(1998)
Mol. Cell
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
-
16
-
-
0037451357
-
Transcriptional activation of the NF-κB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)
-
Vermeulen, L., De Wilde, G., Van Damme, P., Vanden Berghe, W., and Haegeman, G. (2003) Transcriptional activation of the NF-κB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1). EMBO J. 22, 1313-1324
-
(2003)
EMBO J.
, vol.22
, pp. 1313-1324
-
-
Vermeulen, L.1
De Wilde, G.2
Van Damme, P.3
Vanden Berghe, W.4
Haegeman, G.5
-
17
-
-
0032589462
-
IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain
-
Sakurai, H., Chiba, H., Miyoshi, H., Sugita, T., and Toriumi, W. (1999) IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain. J. Biol. Chem. 274, 30353-30356
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30353-30356
-
-
Sakurai, H.1
Chiba, H.2
Miyoshi, H.3
Sugita, T.4
Toriumi, W.5
-
18
-
-
0034693133
-
Tumor necrosis factor α-induced phosphorylation of RelA/p65 on Ser-529 is controlled by casein kinase II
-
Wang, D., Westerheide, S. D., Hanson, J. L., and Baldwin, A. S., Jr. (2000) Tumor necrosis factor α-induced phosphorylation of RelA/p65 on Ser-529 is controlled by casein kinase II. J. Biol. Chem. 275, 32592-32597
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32592-32597
-
-
Wang, D.1
Westerheide, S.D.2
Hanson, J.L.3
Baldwin, A.S.4
-
19
-
-
33646538506
-
Inducible phosphorylation of NF-κB p65 at serine 468 by T cell costimulation is mediated by IKK epsilon
-
Mattioli, I., Geng, H., Sebald, A., Hodel, M., Bucher, C., Kracht, M., and Schmitz, M. L. (2006) Inducible phosphorylation of NF-κB p65 at serine 468 by T cell costimulation is mediated by IKK epsilon. J. Biol. Chem. 281, 6175-6183
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 6175-6183
-
-
Mattioli, I.1
Geng, H.2
Sebald, A.3
Hodel, M.4
Bucher, C.5
Kracht, M.6
Schmitz, M.L.7
-
20
-
-
9644262497
-
Phosphorylation of serine 468 by GSK-3β negatively regulates basal p65 NF-κB activity
-
Buss, H., Dörrie, A., Schmitz, M. L., Frank, R., Livingstone, M., Resch, K., and Kracht, M. (2004) Phosphorylation of serine 468 by GSK-3β negatively regulates basal p65 NF-κB activity. J. Biol. Chem. 279, 49571-49574
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49571-49574
-
-
Buss, H.1
Dörrie, A.2
Schmitz, M.L.3
Frank, R.4
Livingstone, M.5
Resch, K.6
Kracht, M.7
-
21
-
-
70349490830
-
Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NF-κB
-
Lu, T., Jackson, M. W., Singhi, A. D., Kandel, E. S., Yang, M., Zhang, Y., Gudkov, A. V., and Stark, G. R. (2009) Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NF-κB. Proc. Natl. Acad. Sci. U.S.A. 106, 16339-16344
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 16339-16344
-
-
Lu, T.1
Jackson, M.W.2
Singhi, A.D.3
Kandel, E.S.4
Yang, M.5
Zhang, Y.6
Gudkov, A.V.7
Stark, G.R.8
-
22
-
-
2342510148
-
Secreted transforming growth factor β2 activates NF-κB, blocks apoptosis and is essential for the survival of some tumor cells
-
Lu, T., Burdelya, L. G., Swiatkowski, S. M., Boiko, A. D., Howe, P. H., Stark, G. R., and Gudkov, A. V. (2004) Secreted transforming growth factor β2 activates NF-κB, blocks apoptosis and is essential for the survival of some tumor cells. Proc. Natl. Acad. Sci. U.S.A. 101, 7112-7117
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 7112-7117
-
-
Lu, T.1
Burdelya, L.G.2
Swiatkowski, S.M.3
Boiko, A.D.4
Howe, P.H.5
Stark, G.R.6
Gudkov, A.V.7
-
23
-
-
76249100563
-
Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65
-
Lu, T., Jackson, M. W., Wang, B., Yang, M., Chance, M. R., Miyagi, M., Gudkov, A. V., and Stark, G. R. (2010) Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65. Proc. Natl. Acad. Sci. U.S.A. 107, 46-51
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 46-51
-
-
Lu, T.1
Jackson, M.W.2
Wang, B.3
Yang, M.4
Chance, M.R.5
Miyagi, M.6
Gudkov, A.V.7
Stark, G.R.8
-
24
-
-
84882370181
-
Role of lysine methylation of NF-κB in differential gene regulation
-
Lu, T., Yang, M., Huang, D. B., Wei, H., Ozer, G. H., Ghosh, G., and Stark, G. R. (2013) Role of lysine methylation of NF-κB in differential gene regulation. Proc. Natl. Acad. Sci. U.S.A. 110, 13510-13515
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 13510-13515
-
-
Lu, T.1
Yang, M.2
Huang, D.B.3
Wei, H.4
Ozer, G.H.5
Ghosh, G.6
Stark, G.R.7
-
25
-
-
84880869807
-
The complexity of NF-κB signaling in inflammation and cancer
-
Hoesel, B., and Schmid, J. A. (2013) The complexity of NF-κB signaling in inflammation and cancer. Mol. Cancer 12, 86
-
(2013)
Mol. Cancer
, vol.12
, pp. 86
-
-
Hoesel, B.1
Schmid, J.A.2
-
26
-
-
0032491485
-
Activation of nuclear factor-κB-dependent transcription by tumor necrosis factor-α is mediated through phosphorylation of RelA/p65 on serine 529
-
Wang, D., and Baldwin, A. S., Jr. (1998) Activation of nuclear factor-κB-dependent transcription by tumor necrosis factor-α is mediated through phosphorylation of RelA/p65 on serine 529. J. Biol. Chem. 273, 29411-29416
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29411-29416
-
-
Wang, D.1
Baldwin, A.S.2
-
27
-
-
33947103658
-
A curated compendium of phosphorylation motifs
-
Amanchy, R., Periaswamy, B., Mathivanan, S., Reddy, R., Tattikota, S. G., and Pandey, A. (2007) A curated compendium of phosphorylation motifs. Nat. Biotechnol. 25, 285-286
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 285-286
-
-
Amanchy, R.1
Periaswamy, B.2
Mathivanan, S.3
Reddy, R.4
Tattikota, S.G.5
Pandey, A.6
-
28
-
-
0032720628
-
Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and platelet-activating factor synthesis is Flk-1-dependent
-
Bernatchez, P. N., Soker, S., and Sirois, M. G. (1999) Vascular endothelial growth factor effect on endothelial cell proliferation, migration, and platelet-activating factor synthesis is Flk-1-dependent. J. Biol. Chem. 274, 31047-31054
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31047-31054
-
-
Bernatchez, P.N.1
Soker, S.2
Sirois, M.G.3
-
29
-
-
34249825478
-
Vascular endothelial growth factor and its relationship to inflammatory mediators
-
Angelo, L. S., and Kurzrock, R. (2007) Vascular endothelial growth factor and its relationship to inflammatory mediators. Clin. Cancer Res. 13, 2825-2830
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 2825-2830
-
-
Angelo, L.S.1
Kurzrock, R.2
-
30
-
-
84926430176
-
Cancer prevention and therapy through the modulation of the tumor microenvironment
-
Casey, S. C., Amedei, A., Aquilano, K., Azmi, A. S., Benencia, F., Bhakta, D., Bilsland, A. E., Boosani, C. S., Chen, S., Ciriolo, M. R., Crawford, S., Fujii, H., Georgakilas, A. G., Guha, G., Halicka, D., Helferich, W. G., Heneberg, P., Honoki, K., Keith, W. N., Kerkar, S. P., Mohammed, S. I., Niccolai, E., Nowsheen, S., Vasantha Rupasinghe, H. P., Samadi, A., Singh, N., Talib, W. H., Venkateswaran, V., Whelan, R. L., Yang, X., and Felsher, D. W. (2015) Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin Cancer Biol. 10.1016/j.semcancer.2015.02.007
-
(2015)
Semin Cancer Biol.
-
-
Casey, S.C.1
Amedei, A.2
Aquilano, K.3
Azmi, A.S.4
Benencia, F.5
Bhakta, D.6
Bilsland, A.E.7
Boosani, C.S.8
Chen, S.9
Ciriolo, M.R.10
Crawford, S.11
Fujii, H.12
Georgakilas, A.G.13
Guha, G.14
Halicka, D.15
Helferich, W.G.16
Heneberg, P.17
Honoki, K.18
Keith, W.N.19
Kerkar, S.P.20
Mohammed, S.I.21
Niccolai, E.22
Nowsheen, S.23
Vasantha Rupasinghe, H.P.24
Samadi, A.25
Singh, N.26
Talib, W.H.27
Venkateswaran, V.28
Whelan, R.L.29
Yang, X.30
Felsher, D.W.31
more..
-
31
-
-
84904662259
-
The CK1 family: Contribution to cellular stress response and its role in carcinogenesis
-
Knippschild, U., Krüger, M., Richter, J., Xu, P., García-Reyes, B., Peifer, C., Halekotte, J., Bakulev, V., and Bischof, J. (2014) The CK1 family: contribution to cellular stress response and its role in carcinogenesis. Front. Oncol. 4, 96
-
(2014)
Front. Oncol.
, vol.4
, pp. 96
-
-
Knippschild, U.1
Krüger, M.2
Richter, J.3
Xu, P.4
García-Reyes, B.5
Peifer, C.6
Halekotte, J.7
Bakulev, V.8
Bischof, J.9
-
32
-
-
32644451364
-
CKI, there's more than one: Casein kinase I family members in Wnt and Hedgehog signaling
-
Price, M. A. (2006) CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling. Genes Dev. 20, 399-410
-
(2006)
Genes Dev.
, vol.20
, pp. 399-410
-
-
Price, M.A.1
-
33
-
-
11244285329
-
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKε, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription
-
Buss, H., Dörrie, A., Schmitz, M. L., Hoffmann, E., Resch, K., and Kracht, M. (2004) Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKε, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. J. Biol. Chem. 279, 55633-55643
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 55633-55643
-
-
Buss, H.1
Dörrie, A.2
Schmitz, M.L.3
Hoffmann, E.4
Resch, K.5
Kracht, M.6
-
34
-
-
0033961280
-
Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB
-
Madrid, L. V., Wang, C. Y., Guttridge, D. C., Schottelius, A. J., Baldwin, A. S., Jr., and Mayo, M. W. (2000) Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB. Mol. Cell Biol. 20, 1626-1638
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 1626-1638
-
-
Madrid, L.V.1
Wang, C.Y.2
Guttridge, D.C.3
Schottelius, A.J.4
Baldwin, A.S.5
Mayo, M.W.6
-
35
-
-
0042525909
-
Essential role of RelA Ser311 phosphorylation by ζPKC in NF-κB transcriptional activation
-
Duran, A., Diaz-Meco, M. T., and Moscat, J. (2003) Essential role of RelA Ser311 phosphorylation by ζPKC in NF-κB transcriptional activation. EMBO J. 22, 3910-3918
-
(2003)
EMBO J.
, vol.22
, pp. 3910-3918
-
-
Duran, A.1
Diaz-Meco, M.T.2
Moscat, J.3
|