A Drosophila model for mito-nuclear diseases generated by an incompatible interaction between tRNA and tRNA synthetase

DMM Disease Models and Mechanisms

Volumn 8, Issue 8, 2015, Pages 843-854

  Holmbeck, Marissa A ^a   Donner, Julia R ^b   Villa Cuesta, Eugenia ^c   Rand, David M ^b  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

^c ADELPHI UNIVERSITY   (United States)

Author keywords

Disease; Epistasis; Mitochondria

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; MITOCHONDRIAL DNA; TRANSFER RNA; TYROSINE;

ALLELE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DROSOPHILA MELANOGASTER; DROSOPHILA SIMULANS; ENZYME ACTIVITY; EPISTASIS; GENE INTERACTION; GENE MUTATION; GENOTYPE; INTERACTIONS WITH RNA; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL VOLUME; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; TRANSLATION INITIATION; UPREGULATION; ANATOMY AND HISTOLOGY; ANIMAL; ANIMAL STRUCTURES; CELL NUCLEUS; CELL RESPIRATION; DISEASE MODEL; FLYING; GENETICS; METABOLISM; MOTOR ACTIVITY; MUSCLE; MUSCLE MITOCHONDRION; RNA TRANSLATION; TRANSGENIC ANIMAL; ULTRASTRUCTURE;

DROSOPHILA MELANOGASTER; DROSOPHILA SIMULANS; VASCONCELLEA CANDICANS;

AMINO ACYL-TRNA SYNTHETASES; ANIMAL STRUCTURES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL NUCLEUS; CELL RESPIRATION; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; EPISTASIS, GENETIC; FLIGHT, ANIMAL; GENOTYPE; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL DISEASES; MOTOR ACTIVITY; MUSCLES; OXIDATIVE PHOSPHORYLATION; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; RNA, TRANSFER; TYROSINE;

EID: 84939528621     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.019323     Document Type: Article

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