Genome-wide expression profiles identify potential targets for gene-environment interactions in asthma severity

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 4, 2015, Pages 885-892.e2

  Sordillo, Joanne E ^a   Kelly, Roxanne ^a   Bunyavanich, Supinda ^b   McGeachie, Michael ^a   Qiu, Weiliang ^a   Croteau Chonka, Damien C ^a   Soto Quiros, Manuel ^c   Avila, Lydiana ^c   Celedón, Juan C ^c   Brehm, John M ^d   Weiss, Scott T ^a   Gold, Diane R ^a   Litonjua, Augusto A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c HOSPITAL NACIONAL DE NIÑOS   (Costa Rica)

^d CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

asthma exacerbation; asthma severity; Dust mite allergen; gene expression; IL 9

Indexed keywords

ALLERGEN; CLAUDIN; CLAUDIN 9; INTERLEUKIN 5; INTERLEUKIN 9; PROTEOGLYCAN; PROTEOGLYCAN 2; UNCLASSIFIED DRUG; ARTHROPOD PROTEIN; CYSTEINE PROTEINASE; DERMATOPHAGOIDES FARINAE ANTIGEN F 1; HOUSE DUST ALLERGEN; MAJOR BASIC PROTEIN; PRG2 PROTEIN, HUMAN; TRANSCRIPTOME;

ARTICLE; ASTHMA; CHILD; COHORT ANALYSIS; COSTA RICA; DERMATOPHAGOIDES FARINAE; DISEASE EXACERBATION; DISEASE SEVERITY; ENVIRONMENTAL EXPOSURE; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HOUSE DUST; HUMAN; IN VITRO STUDY; LUNG FUNCTION; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; META ANALYSIS (TOPIC); PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUESTIONNAIRE; RESPIRATORY TRACT ALLERGY; SENSITIZATION; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN TEST; ADVERSE EFFECTS; ANIMAL; CELL CULTURE; DISEASE COURSE; EMERGENCY HEALTH SERVICE; FOLLOW UP; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; PHYSIOLOGY; PRESCHOOL CHILD; PUERTO RICO; UNITED STATES; UPREGULATION;

ANIMALS; ANTIGENS, DERMATOPHAGOIDES; ARTHROPOD PROTEINS; ASTHMA; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; COSTA RICA; CYSTEINE ENDOPEPTIDASES; DERMATOPHAGOIDES FARINAE; DISEASE PROGRESSION; EMERGENCY MEDICAL SERVICES; ENVIRONMENTAL EXPOSURE; EOSINOPHIL MAJOR BASIC PROTEIN; FEMALE; FOLLOW-UP STUDIES; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INTERLEUKIN-5; INTERLEUKIN-9; LEUKOCYTES, MONONUCLEAR; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEOGLYCANS; PUERTO RICO; TRANSCRIPTOME; UNITED STATES; UP-REGULATION;

EID: 84939526645     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.02.035     Document Type: Article

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