Mediators, Receptors, and Signalling Pathways in the Anti-Inflammatory and Antihyperalgesic Effects of Acupuncture

Evidence-based Complementary and Alternative Medicine

Volumn 2015, Issue , 2015, Pages

  McDonald, John L ^a   Cripps, Allan W ^a   Smith, Peter K ^a  

^a GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; CHEMOKINE; CYTOKINE; NEUROPEPTIDE; NEUROTROPHIN; RECEPTOR; VANILLOID RECEPTOR 1;

ACUPUNCTURE; ALLERGIC RHINITIS; ALLODYNIA; EDEMA; HUMAN; INFLAMMATORY PAIN; MOLECULAR INTERACTION; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; THERAPY EFFECT;

EID: 84939477532     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2015/975632     Document Type: Review

References (66)

1. J. L. McDonald, A. W. Cripps, P. K. Smith, C. A. Smith, C. C. Xue, and B. Golianu, "The anti-inflammatory effects of acupuncture and their relevance to allergic rhinitis: A narrative review and proposed model, " Evidence-Based Complementary and AlternativeMedicine, vol. 2013, Article ID 591796, 12 pages, 2013.
2. A. Li, L. Lao, Y. Wang et al., "Electroacupuncture activates corticotrophin-releasing hormone-containing neurons in the paraventricular nucleus of the hypothalammus to alleviate edema in a rat model of inflammation, " BMC Complementary and Alternative Medicine, vol. 8, article 20, 2008.
3. A. Li, R.-X. Zhang, Y. Wang et al., "Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation, " BMC Complementary and AlternativeMedicine, vol. 7, article 27, 2007.
4. J.-Y. Du, J.-Q. Fang, Y. Liang, and J.-F. Fang, "Electroacupuncture attenuates mechanical allodynia by suppressing the spinal JNK1/2 pathway in a rat model of inflammatory pain, " Brain Research Bulletin, vol. 108, pp. 27-36, 2014.
5. J.-Q. Fang, J.-Y. Du, Y. Liang, and J.-F. Fang, "Intervention of electroacupuncture on spinal p38MAPK/ATF-2/VR-1 pathway in treating inflammatory pain induced by CFA in rats, " Molecular Pain, vol. 9, no. 1, article 13, 2013.
6. H.-W. Kim, D.-H. Roh, S.-Y. Yoon et al., "The anti-inflammatory effects of low-And high-frequency electroacupuncture are mediated by peripheral opioids in a mouse air pouch inflammation model, " Journal of Alternative and Complementary Medicine, vol. 12, no. 1, pp. 39-44, 2006.
7. R. Sekido, K. Ishimaru, and M. Sakita, "Differences of electroacupuncture-induced analgesic effect in normal and inflammatory conditions in rats, " American Journal of Chinese Medicine, vol. 31, no. 6, pp. 955-965, 2003.
8. S. P. Zhang, J. S. Zhang, K. K. L. Yung, and H. Q. Zhang, "Nonopioid-dependent anti-inflammatory effects of low frequency electroacupuncture, " Brain Research Bulletin, vol. 62, no. 4, pp. 327-334, 2004.
9. Y. Wang, D. Hackel, F. Peng, and H. L. Rittner, "Long-Term antinociception by electroacupuncture is mediated via peripheral opioid receptors in free-moving rats with inflammatory hyperalgesia, " European Journal of Pain, vol. 17, no. 10, pp. 1447-1457, 2013.
10. C. Huang, Z.-P. Hu, H. Long, Y.-S. Shi, J.-S. Han, and Y. Wan, "Attenuation of mechanical but not thermal hyperalgesia by electroacupuncture with the involvement of opioids in rat model of chronic inflammatory pain, " Brain Research Bulletin, vol. 63, no. 2, pp. 99-103, 2004.
11. C. Huang, Z.-Q. Huang, Z.-P. Hu et al., "Electroacupuncture effects in a rat model of complete Freunds adjuvant-induced inflammatory pain: Antinociceptive effects enhanced and tolerance development accelerated, " Neurochemical Research, vol. 33, no. 10, pp. 2107-2111, 2008.
12. T.F. Su, L.H. Zhang, M. Peng et al., "CannabinoidCB2receptors contribute to upregulation of beta-endorphin in inflamed skin tissues by electroacupuncture, "Molecular Pain, vol. 7, article 98, 2011.
13. X.-F. Zhang, Y. Zou, Y. Zhao, T.-H. Wang, and W. Zhang, "Effects of eiectroacupuncture of governor vessel acupoints on changes of BDNF in the corticalmotor area of mice with spinal cord transection, " Journal of Sichuan University, vol. 43, no. 2, pp. 250-253, 2012.
14. Y. Shou, Y. Yang, M.-S. Xu, Y.-Q. Zhao, L.-B. Ge, and B.-M. Zhang, "Electroacupuncture inhibition of hyperalgesia in rats with adjuvant arthritis: involvement of cannabinoid receptor 1 and dopamine receptor subtypes in striatum, " Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 393460, 10 pages, 2013.
15. J. Q. Fang, J. F. Fang, Y. Liang, and J.Y. Du, "Electroacupuncture mediates extracellular signal-regulated kinase 1/2 pathways in the spinal cord of rats with inflammatory pain, " BMC Complementary&AlternativeMedicine, vol. 14, no. 1, article 285, 2014.
16. Y. Wang, R. Gehringer, S. A. Mousa, D. Hackel, A. Brack, and H. L. Rittner, "CXCL10 controls inflammatory pain via opioid peptide-containing macrophages in electroacupuncture, " PLoS ONE, vol. 9, no. 4, Article ID e94696, 2014.
17. W.-H. Chen, C.-L. Hsieh, C.-P. Huang et al., "Acid-sensing ion channel 3 mediates peripheral anti-hyperalgesia effects of acupuncture in mice inflammatory pain, " Journal of Biomedical Science, vol. 18, no. 1, article 82, 2011.
18. C.-P. Huang, H.-N. Chen, H.-L. Su et al., "Electroacupuncture reduces carrageenan-And CFA-induced inflammatory pain accompanied by changing the expression of Nav1.7 and Nav1.8, rather than Nav1.9, inmice dorsal root ganglia, " Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 312184, 8 pages, 2013.
19. H. N. Kim, Y. R. Kim, J. Y. Jang, H. K. Shin, and B. T. Choi, "Electroacupuncture inhibits phosphorylation of spinal phosphatidylinositol 3-kinase/Akt in a carrageenan-induced inflammatory rat model, " Brain Research Bulletin, vol. 87, no. 2-3, pp. 199-204, 2012.
20. M. D. da Silva, F. Bobinski, K. L. Sato, S. J. Kolker, K. A. Sluka, and A. R. Santos, "IL-10 cytokine released from M2 macrophages is crucial for analgesic and anti-inflammatory effects of acupuncture in a model of inflammatorymuscle pain, " Molecular Neurobiology, vol. 51, no. 1, pp. 19-31, 2015.
21. H. Y. Kim, J. Wang, I. Lee, H. K. Kim, K. Chung, and J. M. Chung, "Electroacupuncture suppresses capsaicin-induced secondary hyperalgesia through an endogenous spinal opioid mechanism, " Pain, vol. 145, no. 3, pp. 332-340, 2009.
22. H. S. Hwang, E. J. Yang, S.M. Lee, S. C. Lee, and S. Choi, "Antiallodynic effects of electroacupuncture combined with MK-801 treatment through the regulation of p35/p25 in experimental diabetic neuropathy, " Experimental Neurobiology, vol. 20, no. 3, pp. 144-152, 2011.
23. Y.-L. Jiang, X.-H. Yin, Y.-F. Shen, X.-F. He, and J.-Q. Fang, "Low frequency electroacupuncture alleviated spinal nerve ligation induced mechanical allodynia by inhibiting TRPV1 upregulation in ipsilateral undamaged dorsal root ganglia in rats, " Evidence-Based Complementary and AlternativeMedicine, vol. 2013, Article ID 170910, 9 pages, 2013.
24. J. Y. Lee, D. C. Choi, T. H. Oh, and T. Y. Yune, "Analgesic effect of acupuncture is mediated via inhibition of JNK activation in astrocytes after spinal cord injury, " PLoS ONE, vol. 8, no. 9, Article ID e73948, 2013.
25. J. Yu, C. Zhao, and X. Luo, "The effects of electroacupuncture on the extracellular signal-regulated kinase 1/2/P2X3 signal pathway in the spinal cord of rats with chronic constriction injury, " Anesthesia&Analgesia, vol. 116, no. 1, pp. 239-246, 2013.
26. H.-C. Hsu, N.-Y. Tang, Y.-W. Lin, T.-C. Li, H.-J. Liu, and C.-L. Hsieh, "Effect of electroacupuncture on rats with chronic constriction injury-induced neuropathic pain, " The Scientific World Journal, vol. 2014, Article ID 129875, 9 pages, 2014.
27. H.-C. Wang, C.-T. Zuo, and Y.-H. Guan, "Research on receptors related to acupuncture analgesia and positron emission tomography radioligands: A review, " Journal of Chinese Integrative Medicine, vol. 7, no. 6, pp. 575-581, 2009.
28. Y. C. Park, J. H. Jo, K. E. Hong, W. C. Kang, and S. M. Choi, "Effect of acupuncture on nasal obstruction in patients with persistent allergic rhinitis: A randomized, controlled trial, " The Journal of Korean Acupuncture & Moxibustion Society, vol. 22, pp. 229-239, 2005.
29. B. Brinkhaus, M. Ortiz, C. M. Witt et al., "Acupuncture in patients with seasonal allergic rhinitis: A randomized trial, " Annals of Internal Medicine, vol. 158, no. 4, pp. 225-234, 2013.
30. S. M. Choi, J. E. Park, S.-S. Li et al., "Amulticenter, randomized, controlled trial testing the effects of acupuncture on allergic rhinitis, " Allergy, vol. 68, no. 3, pp. 365-374, 2013.
31. Y. Q. Rao and N. Y. Han, "Therapeutic effect of acupuncture on allergic rhinitis and its effects on immunologic function, " Zhongguo Zhen Jiu, vol. 26, pp. 557-560, 2006.
32. C. C. Xue, X. An, T. P. Cheung et al., "Acupuncture for persistent allergic rhinitis: A randomised, sham-controlled trial, " Medical Journal of Australia, vol. 187, no. 6, pp. 337-341, 2007.
33. C. C. Xue, R. English, J. J. Zhang, C. da Costa, and C. G. Li, "Effect of acupuncture in the treatment of seasonal allergic rhinitis: A randomized controlled clinical trial, " The American Journal of Chinese Medicine, vol. 30, no. 1, pp. 1-11, 2002.
34. S. Sarin, B. Undem, A. Sanico, and A. Togias, "The role of the nervous system in rhinitis, " The Journal of Allergy and Clinical Immunology, vol. 118, no. 5, pp. 999-1014, 2006.
35. Y.-M. Li, L.-X. Zhuang, X.-S. Lai, and G.-H. Jiang, "Effects of electroacupuncture on plasma vasoactive intestinal peptide and substance P in perennial allergic rhinitis patients, " Zhen Ci Yan Jiu, vol. 32, no. 2, pp. 136-138, 2007.
36. D. Jung, S. Lee, and S. Hong, "Effects of acupuncture and moxibustion in a mousemodel of allergic rhinitis, " Otolaryngology-Head and Neck Surgery, vol. 146, no. 1, pp. 19-25, 2012.
37. B. Hauswald, C. Dill, J. Boxberger, E. Kuhlisch, T. Zahnert, and Y. M. Yarin, "The effectiveness of acupuncture compared to loratadine in patients allergic to house dust mites, " Journal of Allergy, vol. 2014, Article ID 654632, 7 pages, 2014.
38. F. B. Petti, A. Liguori, and F. Ippoliti, "Study on cytokines IL-2, IL-6, IL-10 in patients of chronic allergic rhinitis treated with acupuncture, " Journal of Traditional Chinese Medicine, vol. 22, no. 2, pp. 104-111, 2002.
39. H.-S. Shiue, Y.-S. Lee, C.-N. Tsai, Y.-M. Hsueh, J.-R. Sheu, and H.-H. Chang, "DNA microarray analysis of the effect on inflammation in patients treated with acupuncture for allergic rhinitis, " Journal of Alternative and Complementary Medicine, vol. 14, no. 6, pp. 689-698, 2008.
40. M.-F. Zheng, C. Lin, L.-P. Zheng, and F.-R. He, "Effects of acupuncture-moxibustion on monocyte Th1/Th2 cytokine in peripheral blood of patients with perennial allergic rhinitis, " Journal of Acupuncture and Tuina Science, vol. 8, no. 2, pp. 85-88, 2010.
41. Y. R. Kim, H. N. Kim, S. M. Ahn, Y. H. Choi, H. K. Shin, and B. T. Choi, "Electroacupuncture promotes post-stroke functional recovery via enhancing endogenous neurogenesis in mouse focal cerebral ischemia, " PLoS ONE, vol. 9, no. 2, Article ID e90000, 2014.
42. J. Liang, J. Lu, S. F. Cui, J. R. Wang, and Y. Tu, "Effect of acupuncture on expression of brain-derived neurotrophic factor gene and protein in frontal cortex and hippocampus of depression rats, " Zhen Ci Yan Jiu, vol. 37, no. 1, pp. 20-24, 2012.
43. D. Lin, I.D. L. Pena, L. Lin, S.-F. Zhou, C. V. Borlongan, and C. Cao, "The neuroprotective role of acupuncture and activation of the BDNF signaling pathway, " International Journal ofMolecular Sciences, vol. 15, no. 2, pp. 3234-3252, 2014.
44. H. Sun, H. Zhao, C. Ma et al., "Effects of electroacupuncture on depression and the production of glial cell line-derived neurotrophic factor compared with fluoxetine: A randomized controlled pilot study, " Journal of Alternative and Complementary Medicine, vol. 19, no. 9, pp. 733-739, 2013.
45. S. Y. Fang and C. L. Shen, "Neuropeptide innervation and neuroendocrine cells in allergic rhinitis and chronic hypertrophic rhinitis, " Clinical and Experimental Allergy, vol. 28, no. 2, pp. 228-232, 1998.
46. J. M. Figueroa, E. Mansilla, and A. M. Suburo, "Innervation of nasal turbinate blood vessels in rhinitic and nonrhinitic children, " American Journal of Respiratory and Critical Care Medicine, vol. 157, no. 6, pp. 1959-1966, 1998.
47. A. Fischer, A. Wussow, A. Cryer et al., "Neuronal plasticity in persistent perennial allergic rhinitis, " Journal of Occupational and Environmental Medicine, vol. 47, no. 1, pp. 20-25, 2005.
48. N. Zhang and J. J. Oppenheim, "Crosstalk between chemokines and neuronal receptors bridges immune and nervous systems, " Journal of Leukocyte Biology, vol. 78, no. 6, pp. 1210-1214, 2005.
49. W. Gao, X. Tang, Z. Chen et al., "Effectsof acupunctureonCCL2 and CXCL8 expression and the subset of uNK cells in rats with embryo implantation failure, " Evidence-Based Complementary and AlternativeMedicine, vol. 2013, Article ID678390, 12 pages, 2013.
50. H. Wei, X. Yao, L. Yang et al., "Glycogen synthase kinase-3 is involved in electroacupuncture pretreatment via the cannabinoid CB1 receptor in ischemic stroke, " Molecular Neurobiology, vol. 49, no. 1, pp. 326-336, 2014.
51. H. Zhou, Z. Zhang, H. Wei et al., "Activation of STAT3 is involved in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptors in rats, " Brain Research, vol. 1529, pp. 154-164, 2013.
52. M. Rocha E Silva, "A brief survey of the history of inflammation. 1978, " Agents and Actions, vol. 43, no. 3-4, pp. 86-90, 1994.
53. Q. T. Dinh, D. A. Groneberg, C. Peiser et al., "Substance P expression in TRPV1 and trkA-positive dorsal root ganglion neurons innervating the mouse lung, " Respiratory Physiology and Neurobiology, vol. 144, no. 1, pp. 15-24, 2004.
54. J. J. Brokaw and G. W. White, "Calcitonin gene-related peptide potentiates substance P-induced plasma extravasation in the rat trachea, " Lung, vol. 170, no. 2, pp. 85-93, 1992.
55. J.-J. Xin, Y.-S. Su, Z.-K. Yang et al., "Effects of electroacupuncture and regional thermal stimulation at Zusanli (ST 36) on pain thresholds of TRPV 1 knock-out mice, " Acupuncture Research, vol. 37, no. 6, pp. 431-439, 2012.
56. W.-S. Shim, M.-H. Tak, M.-H. Lee et al., "TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase, "TheJournal ofNeuroscience, vol. 27, no. 9, pp. 2331-2337, 2007.
57. R.-X. Zhang, B. Liu, J.-T. Qiao et al., "Electroacupuncture suppresses spinal expression of neurokinin-1 receptors induced by persistent inflammation in rats, " Neuroscience Letters, vol. 384, no. 3, pp. 339-343, 2005.
58. K. J. Tracey, "Physiology and immunology of the cholinergic antiinflammatory pathway, "The Journal of Clinical Investigation, vol. 117, no. 2, pp. 289-296, 2007.
59. R. Torres-Rosas, G. Yehia, G. Peña et al., "Dopamine mediates vagal modulation of the immune system by electroacupuncture, " Nature Medicine, vol. 20, no. 3, pp. 291-295, 2014.
60. N. Goldman, M. Chen, T. Fujita et al., "Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture, " Nature Neuroscience, vol. 13, no. 7, pp. 883-888, 2010.
61. T. Takano, X. Chen, F. Luo et al., "Traditional acupuncture triggers a local increase in adenosine in human subjects, " Journal of Pain, vol. 13, no. 12, pp. 1215-1223, 2012.
62. M. Tominaga and T. Tominaga, "Structure and function of TRPV1, " Pflugers Archiv, vol. 451, no. 1, pp. 143-150, 2005.
63. J.W. Little, A. Ford, A. M. Symons-Liguori et al., "Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states, " Brain, vol. 138, no. 1, pp. 28-35, 2015.
64. M. K. Ai, X. M. Guan, C. G. Zhu, and L. L. Vacca, "The influence of electroacupuncture and morphine on Substance P (SP) Enkephalin (ENK) and Acetylcholine Esterase (AChE) in the spinal cord of rats, " Zhen Ci Yan Jiu, vol. 11, pp. 96-105, 1986.
65. I. Kondo, J. C. G. Marvizon, B. B. Song et al., "Inhibition by spinal-And-opioid agonists of afferent-evoked substance P release, " The Journal of Neuroscience, vol. 25, no. 14, pp. 3651-3660, 2005.
66. J. Keeble, F. Russell, B. Curtis, A. Starr, E. Pinter, and S.D. Brain, "Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation, " Arthritis & Rheumatism, vol. 52, no. 10, pp. 3248-3256, 2005.