Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery

Journal of the American Heart Association

Volumn 3, Issue 4, 2014, Pages

  Kochukov, Mikhail Y ^a   Balasubramanian, Adithya ^a   Abramowitz, Joel ^b   Birnbaumer, Lutz ^b   Marrelli, Sean P ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cerebrovascular circulation; Endothelium; Endothelium derived factors; Ion channels; Vasculature

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; PYR3; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; UNCLASSIFIED DRUG; CALCIUM; TRANSIENT RECEPTOR POTENTIAL CHANNEL C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DILATATION; ARTICLE; BRAIN ARTERY; CALCIUM TRANSPORT; CATION TRANSPORT; CELL CULTURE; CELL ISOLATION; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOTHELIUM CELL; HYPERPOLARIZATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PATCH CLAMP TECHNIQUE; POSTERIOR CEREBRAL ARTERY; POTASSIUM CURRENT; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; ANIMAL; GENETICS; MEMBRANE POTENTIAL; METABOLISM; PHYSIOLOGY; VASODILATATION;

ANIMALS; CALCIUM; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; PATCH-CLAMP TECHNIQUES; POSTERIOR CEREBRAL ARTERY; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; TRPC CATION CHANNELS; VASODILATION;

EID: 84939462254     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.114.000913     Document Type: Article

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