Novel antibacterial active quinolone-fluoroquinolone conjugates and 2D-QSAR studies

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 18, 2015, Pages 3816-3821

  Panda, Siva S ^a,b   Liaqat, Sumaira ^a,c   Girgis, Adel S ^d   Samir, Ahmed ^e   Hall, C Dennis ^a   Katritzky, Alan R ^a  

^a University of Florida   (United States)

^b AUGUSTA UNIVERSITY   (United States)

^c THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

^d NATIONAL RESEARCH CENTRE   (Egypt)

^e Cairo University   (Egypt)

Author keywords

Amino acids; Anti bacterial; Conjugates; Fluoroquinolone; QSAR; Quinolone

Indexed keywords

AMINO ACID; ANTIINFECTIVE AGENT; BENZOTRIAZOLE DERIVATIVE; QUINOLONE; QUINOLONE DERIVATIVE; QUINOLONE FLUOROQUINOLONE CONJUGATE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOASSAY; DRUG CONJUGATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; LINEAR REGRESSION ANALYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SALMONELLA ENTERICA SEROVAR TYPHI; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; SYNTHESIS;

BACTERIA (MICROORGANISMS);

ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINOLONES;

EID: 84939261052     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.07.077     Document Type: Article

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