Active Drug Targeting of a Folate-Based Cyclodextrin-Doxorubicin Conjugate and the Cytotoxic Effect on Drug-Resistant Mammary Tumor Cells in Vitro

Journal of Pharmaceutical Sciences

Volumn 104, Issue 9, 2015, Pages 2934-2940

  Mizusako, Hideki ^a   Tagami, Tatsuaki ^a   Hattori, Kenjiro ^b   Ozeki, Tetsuya ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b Nano Dex Inc   (Japan)

Author keywords

cancer; cyclodextrin; drug delivery; drug resistance; folate; per FOL CD; receptor mediated endocytosis; supramolecular chemistry

Indexed keywords

CYCLODEXTRIN; DOXORUBICIN; DRUG CARRIER; FOLATE RECEPTOR; HYDROXYL GROUP; ANTINEOPLASTIC AGENT; FOLIC ACID;

ANIMAL CELL; ARTICLE; BREAST TUMOR; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG TARGETING; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULE; MOUSE; NONHUMAN; PH; PROTEIN EXPRESSION; TUMOR CELL; ANIMAL; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG RESISTANCE; PROCEDURES; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYCLODEXTRINS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, NEOPLASM; FOLIC ACID; MICE;

EID: 84939256404     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24428     Document Type: Article

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