Normal prepulse inhibition and habituation of acoustic startle response in suicidal depressive patients without psychotic symptoms

Journal of Affective Disorders

Volumn 92, Issue 2-3, 2006, Pages 299-303

  Quednow, Boris B ^a,b   Westheide, Jens ^a   Kühn, Kai Uwe ^a   Werner, Petra ^a   Maier, Wolfgang ^a   Hawellek, Barbara ^a   Wagner, Michael ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Acoustic startle response; Biological marker; Depression; Habituation; Prepulse inhibition; Suicide

Indexed keywords

ADULT; ARTICLE; AUDITORY RESPONSE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE MARKER; DISEASE SEVERITY; FEMALE; GENDER; HABITUATION; HUMAN; IMPULSIVENESS; LETHALITY; MALE; MEASUREMENT; MENTAL PATIENT; PREPULSE INHIBITION; PRIORITY JOURNAL; PSYCHOSIS; SMOKING; STARTLE REFLEX; SUICIDAL BEHAVIOR; SUICIDE ATTEMPT; SYMPTOM;

ACOUSTIC STIMULATION; ADOLESCENT; ADULT; BIOLOGICAL MARKERS; DEPRESSIVE DISORDER, MAJOR; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; HABITUATION, PSYCHOPHYSIOLOGIC; HUMANS; MALE; MIDDLE AGED; PSYCHOTIC DISORDERS; REACTIVE INHIBITION; STARTLE REACTION; SUICIDE, ATTEMPTED;

EID: 33646401550     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2006.01.022     Document Type: Article

References (31)

1. Barratt E.S. Factor analysis of some psychometric measures of impulsiveness and anxiety. Psychol. Rep. 16 (1965) 547-554
2. Beck A.T., Schuyler D., and Herman I. Development of suicidal intent scales. In: Beck A.T., Resnik L.P., and Lettierri D. (Eds). The Prediction of Suicide (1974), Charles Press, Bowie, MD 45-56
3. Bertolote J.M., and Fleischmann A. Suicidal behavior prevention: WHO perspectives on research. Am. J. Med. Genet. C. Semin. Med. Genet. 133 (2005) 8-12
4. Booij L., Van der Does W., Benkelfat C., Bremner J.D., Cowen P.J., Fava M., Gillin C., Leyton M., Moore P., Smith K.A., and Van der Kloot W.A. Predictors of mood response to acute tryptophan depletion: a reanalysis. Neuropsychopharmacology 27 (2002) 852-861
5. Braff D.L., Stone C., Callaway E., Geyer M.A., Glick I.D., and Bali L. Prestimulus effects of human startle reflex in normals and schizophrenics. Psychophysiology 15 (1978) 339-343
6. Brent D.A., Bridge J., Johnson B.A., and Connolly J. Suicidal behavior runs in families. A controlled family study of adolescent suicide victims. Arch. Gen. Psychiatry 53 (1996) 1145-1152
7. Carlton P.L., and Advokat C. Attenuated habituation due to parachlorophenylalanine. Pharmacol. Biochem. Behav. 1 (1973) 657-663
8. Conner R.L., Stolk J.M., Barchas J.D., and Levine S. Parachlorophenylalanine and habituation to repetitive auditory startle stimuli in rats. Physiol. Behav. 5 (1970) 1215-1219
9. Courtet P., Jollant F., Castelnau D., Buresi C., and Malafosse A. Suicidal behavior: relationship between phenotype and serotonergic genotype. Am. J. Med. Genet. C. Semin. Med. Genet. 133C (2005) 25-33
10. Fletcher P.J., Selhi Z.F., Azampanah A., and Sills T.L. Reduced brain serotonin activity disrupts prepulse inhibition of the acoustic startle reflex. Effects of 5,7-dihydroxytryptamine and p-chlorophenylalanine. Neuropsychopharmacology 24 (2001) 399-409
11. Geyer M.A., and Braff D.L. Startle habituation and sensorimotor gating in schizophrenia and related animal models. Schizophr. Bull. 13 (1987) 643-668
12. Graham F.K. The more or less startling effects of weak prestimulation. Psychophysiology 12 (1975) 238-248
13. Groves P.M., and Thompson R.F. Habituation: a dual-process theory. Psychol. Rev. 77 (1970) 419-450
14. Hamilton M. Development of a rating scale for primary depressive illness. Br. J. Soc. Clin. Psychol. 6 (1967) 278-296
15. Harris E.C., and Barraclough B. Suicide as an outcome for mental disorders. A meta-analysis. Br. J. Psychiatry 170 (1997) 205-228
16. Kumari V., and Gray J.A. Smoking withdrawal, nicotine dependence and prepulse inhibition of the acoustic startle reflex. Psychopharmacology (Berl) 141 (1999) 11-15
17. Leboyer M., Slama F., Siever L., and Bellivier F. Suicidal disorders: a nosological entity per se?. Am. J. Med. Genet. C. Semin. Med. Genet. 133C (2005) 3-7
18. Lehrl S. Mehrfachwahl-Wortschatz-Intelligenztest (MWT-B). 4th ed. (1999), Hogrefe, Göttingen
19. Ludewig S., and Ludewig K. No prepulse inhibition deficits in patients with unipolar depression. Depress. Anxiety 17 (2003) 224-225
20. Ludewig K., Ludewig S., Seitz A., Obrist M., Geyer M.A., and Vollenweider F.X. The acoustic startle reflex and its modulation: effects of age and gender in humans. Biol. Psychol. 63 (2003) 311-323
21. Mann J.J. The neurobiology of suicide. Nat. Med. 4 (1998) 25-30
22. Mann J.J. Role of the serotonergic system in the pathogenesis of major depression and suicidal behavior. Neuropsychopharmacology 21 (1999) 99S-105S
23. Mieczkowski T.A., Sweeney J.A., Haas G.L., Junker B.W., and Mann J.J. Factor composition of the suicide intent scale. Suicide Life-Threat. Behav. 23 (1993) 37-45
24. Patton J.H., Stanford M.S., and Barrat E.S. Factor structure of the Barrat Impulsiveness Scale. J. Clin. Psychol. 51 (1995) 768-774
25. Perry W., Minassian A., and Feifel D. Prepulse inhibition in patients with non-psychotic major depressive disorder. J. Affect. Disord. 81 (2004) 179-184
26. Phillips M.A., Oxtoby E.K., Langley R.W., Bradshaw C.M., and Szabadi E. Effects of acute tryptophan depletion on prepulse inhibition of the acoustic startle (eyeblink) response and the N1/P2 auditory evoked response in man. J. Psychopharmacol. 14 (2000) 258-265
27. Prinssen E.P., Assie M.B., Koek W., and Kleven M.S. Depletion of 5-HT disrupts prepulse inhibition in rats: dependence on the magnitude of depletion, and reversal by a 5-HT precursor. Neuropsychopharmacology 26 (2002) 340-347
28. Quednow B.B., Kuhn K.U., Stelzenmueller R., Hoenig K., Maier W., and Wagner M. Effects of serotonergic and noradrenergic antidepressants on auditory startle response in patients with major depression. Psychopharmacology (Berl) 175 (2004) 399-406
29. Quednow B.B., Kuhn K.U., Beckmann K., Westheide J., Maier W., and Wagner M. Attenuation of the prepulse inhibition of the acoustic startle response within and between sessions. Biol. Psychol (2005) (Jul 11, Electronic publication ahead of print)
30. Quednow B.B., Wagner M., Westheide J., Beckmann K., Bliesener N., Maier W., and Kuhn K.U. Sensorimotor gating and habituation of the startle response in schizophrenic patients randomly treated with amisulpride or olanzapine. Biol. Psychiatry (2005) (Aug 31, Electronic publication ahead of print)
31. Roy A., De Jong J., and Linnoila M. Cerebrospinal fluid monoamine metabolites and suicidal behavior in depressed patients. A 5-year follow-up study. Arch. Gen. Psychiatry 46 (1989) 609-612