Thiazolidinediones and the risk of asthma exacerbation among patients with diabetes: A cohort study

Allergy, Asthma and Clinical Immunology

Volumn 10, Issue 1, 2014, Pages

  Rinne, Seppo T ^a,b   Feemster, Laura C ^a,b   Collins, Bridget F ^a,b   Au, David H ^a,b   Perkins, Mark ^a   Bryson, Christopher L ^a,c   O'Riordan, Thomas G ^d   Liu, Chuan Fen ^a,b  

^a VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d Gilead Sciences Inc ^*  (United States)

Author keywords

Asthma; Cohort study; Glitazones; Peroxisome proliferator activated receptors; Thiazolidinediones

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; GLITAZONE DERIVATIVE; ORAL ANTIDIABETIC AGENT; STEROID;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; COHORT ANALYSIS; CORTICOSTEROID THERAPY; DIABETES MELLITUS; DIABETIC PATIENT; DISEASE EXACERBATION; DRUG EXPOSURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MIDDLE AGED; PATIENT COMPLIANCE; PRESCRIPTION; RISK REDUCTION; VETERAN;

EID: 84939223343     PISSN: 17101484     EISSN: 17101492     Source Type: Journal    
DOI: 10.1186/1710-1492-10-34     Document Type: Article

References (40)

1. Barnett SB, Nurmagambetov TA. Costs of asthma in the United States: 2002-2007. J Allergy Clin Immunol 2011, 127(1):145-152.
2. Akinbami L. Asthma Prevalence, Health Care Use and Mortality: United States, 2003-05. NCHS Health E-Stat 2005, CDC, http://www.cdc.gov/nchs/data/hestat/asthma03-05/asthma03-05.htm.
3. Expert Panel Report 3 (EPR-3) Guidelines for the diagnosis and management of asthma-summary report 2007. J Allergy Clin Immunol 2007, 120(5 Suppl):S94-S138. Expert Panel Report 3 (EPR-3).
4. Gamble J, Stevenson M, McClean E, Heaney LG. The prevalence of nonadherence in difficult asthma. Am J Respir Crit Care Med 2009, 180(9):817-822.
5. Chung KF, Godard P, Adelroth E, Ayres J, Barnes N, Barnes P, Bel E, Burney P, Chanez P, Connett G, Corrigan C, de Blic J, Fabbri L, Holgate ST, Ind P, Joos G, Kerstjens H, Leuenberger P, Lofdahl CG, McKenzie S, Magnussen H, Postma D, Saetta M, Salmeron S, Sterk P. Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies: ERS Task Force on Difficult/Therapy-Resistant Asthma: European Respiratory Society. Eur Respir J 1999, 13(5):1198-1208.
6. Consoli A, Devangelio E. Thiazolidinediones and inflammation. Lupus 2005, 14(9):794-797.
7. Spiegelman BM. PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes 1998, 47(4):507-514.
8. Dubuquoy L, Dharancy S, Nutten S, Pettersson S, Auwerx J, Desreumaux P. Role of peroxisome proliferator-activated receptor gamma and retinoid X receptor heterodimer in hepatogastroenterological diseases. Lancet 2002, 360(9343):1410-1418.
9. Spears M, McSharry C, Thomson NC. Peroxisome proliferator-activated receptor-gamma agonists as potential anti-inflammatory agents in asthma and chronic obstructive pulmonary disease. Clin Exp Allergy 2006, 36(12):1494-1504.
10. Hammad H, de Heer HJ, Soullie T, Angeli V, Trottein F, Hoogsteden HC, Lambrecht BN. Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma. Am J Pathol 2004, 164(1):263-271.
11. Lee KS, Park SJ, Hwang PH, Yi HK, Song CH, Chai OH, Kim JS, Lee MK, Lee YC. PPAR-gamma modulates allergic inflammation through up-regulation of PTEN. FASEB J 2005, 19(8):1033-1035.
12. Mueller C, Weaver V, Vanden Heuvel JP, August A, Cantorna MT. Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma. Arch Biochem Biophys 2003, 418(2):186-196.
13. Narala VR, Ranga R, Smith MR, Berlin AA, Standiford TJ, Lukacs NW, Reddy RC. Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma. Respir Res 2007, 8:90.
14. Rhee CK, Lee SY, Kang JY, Kim SJ, Kwon SS, Kim YK, Park SH. Effect of peroxisome proliferator-activated receptor-gamma on airway smooth muscle thickening in a murine model of chronic asthma. Int Arch Allergy Immunol 2009, 148(4):289-296.
15. Trifilieff A, Bench A, Hanley M, Bayley D, Campbell E, Whittaker P. PPAR-alpha and -gamma but not -delta agonists inhibit airway inflammation in a murine model of asthma: in vitro evidence for an NF-kappaB-independent effect. Br J Pharmacol 2003, 139(1):163-171.
16. Park SJ, Lee KS, Kim SR, Min KH, Choe YH, Moon H, Chae HJ, Yoo WH, Lee YC. Peroxisome proliferator-activated receptor gamma agonist down-regulates IL-17 expression in a murine model of allergic airway inflammation. J Immunol 2009, 183(5):3259-3267.
17. Seidel P, Alkhouri H, Lalor DJ, Burgess JK, Armour CL, Hughes JM. Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies. Respir Res 2012, 13:90.
18. Woerly G, Honda K, Loyens M, Papin JP, Auwerx J, Staels B, Capron M, Dombrowicz D. Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation. J Exp Med 2003, 198(3):411-421.
19. Richards DB, Bareille P, Lindo EL, Quinn D, Farrow SN. Treatment with a peroxisomal proliferator activated receptor gamma agonist has a modest effect in the allergen challenge model in asthma: a randomised controlled trial. Respir Med 2010, 104(5):668-674.
20. Sandhu MS, Dimov V, Sandhu AK, Walters RW, Wichman T, Casale T. The use of the peroxisome proliferator-activated receptors gamma agonist rosiglitazone to treat airway hyperreactivity. Ann Allergy Asthma Immunol 2012, 109(1):75-77.
21. Spears M, Donnelly I, Jolly L, Brannigan M, Ito K, McSharry C, Lafferty J, Chaudhuri R, Braganza G, Bareille P, Sweeney L, Adcock IM, Barnes PJ, Wood S, Thomson NC. Bronchodilatory effect of the PPAR-gamma agonist rosiglitazone in smokers with asthma. Clin Pharmacol Ther 2009, 86(1):49-53.
22. Joish VN, Malone DC, Wendel C, Draugalis JR, Mohler MJ. Development and validation of a diabetes mellitus severity index: a risk-adjustment tool for predicting health care resource use and costs. Pharmacotherapy 2005, 25(5):676-684.
23. Ash AS, Ellis RP, Pope GC, Ayanian JZ, Bates DW, Burstin H, Iezzoni LI, MacKay E, Yu W. Using diagnoses to describe populations and predict costs. Health Care Financ Rev 2000, 21(3):7-28.
24. Suissa S. Immortal time bias in pharmaco-epidemiology. Am J Epidemiol 2008, 167(4):492-499.
25. StataCorp Stata Statistical Software: Release 11.2. College Station 2012, TX: StataCorp LP, StataCorp.
26. Bryson CL, Au DH, Young B, McDonell MB, Fihn SD. A refill adherence algorithm for multiple short intervals to estimate refill compliance (ReComp). Med Care 2007, 45(6):497-504.
27. Sin DD, Man J, Sharpe H, Gan WQ, Man SF. Pharmacological management to reduce exacerbations in adults with asthma: a systematic review and meta-analysis. JAMA 2004, 292(3):367-376.
28. Hanania NA, Chapman KR, Kesten S. Adverse effects of inhaled corticosteroids. Am J Med 1995, 98(2):196-208.
29. Blanquart C, Barbier O, Fruchart JC, Staels B, Glineur C. Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation. J Steroid Biochem Mol Biol 2003, 85(2-5):267-273.
30. Daynes RA, Jones DC. Emerging roles of PPARs in inflammation and immunity. Nat Rev Immunol 2002, 2(10):748-759.
31. Patel HJ, Belvisi MG, Bishop-Bailey D, Yacoub MH, Mitchell JA. Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. J Immunol 2003, 170(5):2663-2669.
32. Hashimoto Y, Nakahara K. Improvement of asthma after administration of pioglitazone. Diabetes Care 2002, 25(2):401.
33. Lipscombe LL, Gomes T, Levesque LE, Hux JE, Juurlink DN, Alter DA. Thiazolidinediones and cardiovascular outcomes in older patients with diabetes. JAMA 2007, 298(22):2634-2643.
34. Ferwana M, Firwana B, Hasan R, Al-Mallah MH, Kim S, Montori VM, Murad MH. Pioglitazone and risk of bladder cancer: a meta-analysis of controlled studies. Diabet Med 2013, 30(9):1026-1032.
35. Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007, 356(24):2457-2471.
36. Ray WA. Evaluating medication effects outside of clinical trials: new-user designs. Am J Epidemiol 2003, 158(9):915-920.
37. Thomson NC, Chaudhuri R, Livingston E. Asthma and cigarette smoking. Eur Respir J 2004, 24(5):822-833.
38. Fitzpatrick S, Joks R, Silverberg JI. Obesity is associated with increased asthma severity and exacerbations, and increased serum immunoglobulin E in inner-city adults. Clin Exp Allergy 2012, 42(5):747-759.
39. Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Szefler SJ, Sullivan SD, Thomas MD, Wenzel SE, Reddel HK. A new perspective on concepts of asthma severity and control. Eur Respir J 2008, 32(3):545-554.
40. Johnston NW, Sears MR. Asthma exacerbations: 1: epidemiology. Thorax 2006, 61(8):722-728.