메뉴 건너뛰기




Volumn 42, Issue 5, 2012, Pages 747-759

Obesity is associated with increased asthma severity and exacerbations, and increased serum immunoglobulin E in inner-city adults

Author keywords

Asthma; Asthma severity; Atopy; Basophil; BMI; Class I, II and III obesity; Eosinophil; Forced expiratory volume in 1 s (FEV1); Forced vital capacity (FVC); Immunoglobulin E; Leukocyte; Lymphocyte; Monocyte; Neutrophil; Obesity; Overweight; Peak flow; Pulmonary function test; Spirometry; Weight; Wheeze; White blood cell

Indexed keywords

CORTICOSTEROID; IMMUNOGLOBULIN E;

EID: 84859999742     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03863.x     Document Type: Article
Times cited : (59)

References (67)
  • 2
    • 0037048669 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2000
    • Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 2002; 288:1723-7.
    • (2002) JAMA , vol.288 , pp. 1723-1727
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Johnson, C.L.4
  • 3
    • 74549140993 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2008
    • Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010; 303:235-41.
    • (2010) JAMA , vol.303 , pp. 235-241
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Curtin, L.R.4
  • 4
    • 77956913429 scopus 로고    scopus 로고
    • Trends in asthma prevalence and incidence in Ontario, Canada, 1996-2005: a population study
    • Gershon AS, Guan J, Wang C, To T. Trends in asthma prevalence and incidence in Ontario, Canada, 1996-2005: a population study. Am J Epidemiol 2010; 172:728-36.
    • (2010) Am J Epidemiol , vol.172 , pp. 728-736
    • Gershon, A.S.1    Guan, J.2    Wang, C.3    To, T.4
  • 5
    • 84855283737 scopus 로고    scopus 로고
    • Asthma prevalence, health care use, and mortality: United States, 2005-2009
    • National Center for Health Statistics, Hyattsville, MD
    • Akinbami LJ, Moorman JE, Liu X. Asthma prevalence, health care use, and mortality: United States, 2005-2009. Natl Health Stat Report. National Center for Health Statistics, Hyattsville, MD, 2011.
    • (2011) Natl Health Stat Report.
    • Akinbami, L.J.1    Moorman, J.E.2    Liu, X.3
  • 6
    • 34547227547 scopus 로고    scopus 로고
    • The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis
    • Wang Y, Beydoun MA. The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis. Epidemiol Rev 2007; 29:6-28.
    • (2007) Epidemiol Rev , vol.29 , pp. 6-28
    • Wang, Y.1    Beydoun, M.A.2
  • 9
    • 33846890411 scopus 로고    scopus 로고
    • Obesity and asthma: lessons from animal models
    • Shore SA. Obesity and asthma: lessons from animal models. J Appl Physiol 2007; 102:516-28.
    • (2007) J Appl Physiol , vol.102 , pp. 516-528
    • Shore, S.A.1
  • 10
    • 33646367876 scopus 로고    scopus 로고
    • Obesity and asthma: cause for concern
    • Shore SA. Obesity and asthma: cause for concern. Curr Opin Pharmacol 2006; 6:230-6.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 230-236
    • Shore, S.A.1
  • 13
    • 33344462192 scopus 로고    scopus 로고
    • Higher BMI is associated with worse asthma control and quality of life but not asthma severity
    • Lavoie KL, Bacon SL, Labrecque M, Cartier A, Ditto B. Higher BMI is associated with worse asthma control and quality of life but not asthma severity. Respir Med 2006; 100:648-57.
    • (2006) Respir Med , vol.100 , pp. 648-657
    • Lavoie, K.L.1    Bacon, S.L.2    Labrecque, M.3    Cartier, A.4    Ditto, B.5
  • 14
    • 45849115141 scopus 로고    scopus 로고
    • Is obesity associated with an increased risk for airway hyperresponsiveness and development of asthma?
    • Sharma S, Tailor A, Warrington R, Cheang M. Is obesity associated with an increased risk for airway hyperresponsiveness and development of asthma? Allergy Asthma Clin Immunol 2008; 4:51-8.
    • (2008) Allergy Asthma Clin Immunol , vol.4 , pp. 51-58
    • Sharma, S.1    Tailor, A.2    Warrington, R.3    Cheang, M.4
  • 15
    • 33747784873 scopus 로고    scopus 로고
    • Obesity and asthma
    • Chinn S. Obesity and asthma. Paediatr Respir Rev 2006; 7:223-8.
    • (2006) Paediatr Respir Rev , vol.7 , pp. 223-228
    • Chinn, S.1
  • 16
    • 33748846563 scopus 로고    scopus 로고
    • The association between obesity and asthma is stronger in nonallergic than allergic adults
    • Chen Y, Dales R, Jiang Y. The association between obesity and asthma is stronger in nonallergic than allergic adults. Chest 2006; 130:890-5.
    • (2006) Chest , vol.130 , pp. 890-895
    • Chen, Y.1    Dales, R.2    Jiang, Y.3
  • 17
    • 67349188114 scopus 로고    scopus 로고
    • Association of obesity with IgE levels and allergy symptoms in children and adolescents: results from the National Health and Nutrition Examination Survey 2005-2006
    • 69 e1-4.
    • Visness CM, London SJ, Daniels JL et al. Association of obesity with IgE levels and allergy symptoms in children and adolescents: results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol 2009; 123:1163-9, 69 e1-4.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 1163-1169
    • Visness, C.M.1    London, S.J.2    Daniels, J.L.3
  • 18
    • 77954876109 scopus 로고    scopus 로고
    • Association between obesity and the prevalence of allergic diseases, atopy, and bronchial hyperresponsiveness in Korean adolescents
    • Yoo S, Kim HB, Lee SY et al. Association between obesity and the prevalence of allergic diseases, atopy, and bronchial hyperresponsiveness in Korean adolescents. Int Arch Allergy Immunol 2011; 154:42-8.
    • (2011) Int Arch Allergy Immunol , vol.154 , pp. 42-48
    • Yoo, S.1    Kim, H.B.2    Lee, S.Y.3
  • 19
    • 78649274468 scopus 로고    scopus 로고
    • Obesity, insulin resistance and the prevalence of atopy and asthma in US adults
    • Ma J, Xiao L, Knowles SB. Obesity, insulin resistance and the prevalence of atopy and asthma in US adults. Allergy 2010; 65:1455-63.
    • (2010) Allergy , vol.65 , pp. 1455-1463
    • Ma, J.1    Xiao, L.2    Knowles, S.B.3
  • 20
    • 68949198770 scopus 로고    scopus 로고
    • Atopy, obesity, and asthma in adults: the Humboldt study
    • Chen Y, Rennie D, Cormier Y, Dosman J. Atopy, obesity, and asthma in adults: the Humboldt study. J Agromedicine 2009; 14:222-7.
    • (2009) J Agromedicine , vol.14 , pp. 222-227
    • Chen, Y.1    Rennie, D.2    Cormier, Y.3    Dosman, J.4
  • 21
    • 0034778713 scopus 로고    scopus 로고
    • Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III
    • von Mutius E, Schwartz J, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National Health and Nutrition Examination Study III. Thorax 2001; 56:835-8.
    • (2001) Thorax , vol.56 , pp. 835-838
    • von Mutius, E.1    Schwartz, J.2    Neas, L.M.3    Dockery, D.4    Weiss, S.T.5
  • 22
    • 79955632907 scopus 로고    scopus 로고
    • Association between obesity and atopic dermatitis in childhood: a case-control study
    • Silverberg JI, Kleiman E, Lev-Tov H et al. Association between obesity and atopic dermatitis in childhood: a case-control study. J Allergy Clin Immunol 2011; 127:1180-6.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1180-1186
    • Silverberg, J.I.1    Kleiman, E.2    Lev-Tov, H.3
  • 23
    • 0032898751 scopus 로고    scopus 로고
    • Birth weight, body mass index and asthma in young adults
    • Shaheen SO, Sterne JA, Montgomery SM, Azima H. Birth weight, body mass index and asthma in young adults. Thorax 1999; 54:396-402.
    • (1999) Thorax , vol.54 , pp. 396-402
    • Shaheen, S.O.1    Sterne, J.A.2    Montgomery, S.M.3    Azima, H.4
  • 24
    • 0031925581 scopus 로고    scopus 로고
    • Association of being overweight with greater asthma symptoms in inner city black and Hispanic children
    • Luder E, Melnik TA, DiMaio M. Association of being overweight with greater asthma symptoms in inner city black and Hispanic children. J Pediatr 1998; 132:699-703.
    • (1998) J Pediatr , vol.132 , pp. 699-703
    • Luder, E.1    Melnik, T.A.2    DiMaio, M.3
  • 25
    • 58149160402 scopus 로고    scopus 로고
    • Association between obesity and atopy in Chinese schoolchildren
    • Leung TF, Kong AP, Chan IH et al. Association between obesity and atopy in Chinese schoolchildren. Int Arch Allergy Immunol 2009; 149:133-40.
    • (2009) Int Arch Allergy Immunol , vol.149 , pp. 133-140
    • Leung, T.F.1    Kong, A.P.2    Chan, I.H.3
  • 26
    • 65349133560 scopus 로고    scopus 로고
    • Body mass index in Belgian school children and its relationship with sensitization and allergic symptoms
    • Van Gysel D, Govaere E, Verhamme K, Doli E, De Baets F. Body mass index in Belgian school children and its relationship with sensitization and allergic symptoms. Pediatr Allergy Immunol 2009; 20:246-53.
    • (2009) Pediatr Allergy Immunol , vol.20 , pp. 246-253
    • Van Gysel, D.1    Govaere, E.2    Verhamme, K.3    Doli, E.4    De Baets, F.5
  • 29
    • 0347291904 scopus 로고    scopus 로고
    • Asthma and atopy in overweight children
    • Schachter LM, Peat JK, Salome CM. Asthma and atopy in overweight children. Thorax 2003; 58:1031-5.
    • (2003) Thorax , vol.58 , pp. 1031-1035
    • Schachter, L.M.1    Peat, J.K.2    Salome, C.M.3
  • 30
    • 0036286387 scopus 로고    scopus 로고
    • Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey
    • Jarvis D, Chinn S, Potts J, Burney P. Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey. Clin Exp Allergy 2002; 32:831-7.
    • (2002) Clin Exp Allergy , vol.32 , pp. 831-837
    • Jarvis, D.1    Chinn, S.2    Potts, J.3    Burney, P.4
  • 32
    • 1842552109 scopus 로고    scopus 로고
    • Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper
    • Celli BR, MacNee W. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004; 23:932-46.
    • (2004) Eur Respir J , vol.23 , pp. 932-946
    • Celli, B.R.1    MacNee, W.2
  • 35
    • 0031202242 scopus 로고    scopus 로고
    • New NHLBI guidelines for the diagnosis and management of asthma. National Heart, Lung and Blood Institute
    • 1
    • New NHLBI guidelines for the diagnosis and management of asthma. National Heart, Lung and Blood Institute. Lippincott Health Promot Lett 1997; 2:1, 8-9.
    • (1997) Lippincott Health Promot Lett , vol.2 , pp. 8-9
  • 36
    • 31544465518 scopus 로고    scopus 로고
    • Prevalence of class I, II and III obesity in Canada
    • Katzmarzyk PT, Mason C. Prevalence of class I, II and III obesity in Canada. CMAJ 2006; 174:156-7.
    • (2006) CMAJ , vol.174 , pp. 156-157
    • Katzmarzyk, P.T.1    Mason, C.2
  • 38
    • 0000898845 scopus 로고
    • An analysis of variance test for normality (complete samples)
    • Shapiro SS, Wilk MB. An analysis of variance test for normality (complete samples). Biometrika 1965; 52:591-611.
    • (1965) Biometrika , vol.52 , pp. 591-611
    • Shapiro, S.S.1    Wilk, M.B.2
  • 39
    • 50949108389 scopus 로고    scopus 로고
    • The relationship between obesity and asthma severity and control in adults
    • Mosen DM, Schatz M, Magid DJ, Camargo CA Jr. The relationship between obesity and asthma severity and control in adults. J Allergy Clin Immunol 2008; 122:507-11.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 507-511
    • Mosen, D.M.1    Schatz, M.2    Magid, D.J.3    Camargo Jr, C.A.4
  • 40
    • 77953849507 scopus 로고    scopus 로고
    • Obesity and asthma morbidity in a community-based adult cohort in a large urban area: the Chicago Initiative to Raise Asthma Health Equity (CHIRAH)
    • Grammer LC, Weiss KB, Pedicano JB et al. Obesity and asthma morbidity in a community-based adult cohort in a large urban area: the Chicago Initiative to Raise Asthma Health Equity (CHIRAH). J Asthma 2010; 47:491-5.
    • (2010) J Asthma , vol.47 , pp. 491-495
    • Grammer, L.C.1    Weiss, K.B.2    Pedicano, J.B.3
  • 41
    • 67651213554 scopus 로고    scopus 로고
    • Does higher body mass index contribute to worse asthma control in an urban population?
    • Clerisme-Beaty EM, Karam S, Rand C et al. Does higher body mass index contribute to worse asthma control in an urban population? J Allergy Clin Immunol 2009; 124:207-12.
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 207-212
    • Clerisme-Beaty, E.M.1    Karam, S.2    Rand, C.3
  • 42
    • 0026051430 scopus 로고
    • Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children
    • Sears MR, Burrows B, Flannery EM, Herbison GP, Hewitt CJ, Holdaway MD. Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children. N Engl J Med 1991; 325:1067-71.
    • (1991) N Engl J Med , vol.325 , pp. 1067-1071
    • Sears, M.R.1    Burrows, B.2    Flannery, E.M.3    Herbison, G.P.4    Hewitt, C.J.5    Holdaway, M.D.6
  • 44
    • 0031000588 scopus 로고    scopus 로고
    • Elevated expression of transforming growth factor-beta in adipose tissue from obese mice
    • Samad F, Yamamoto K, Pandey M, Loskutoff DJ. Elevated expression of transforming growth factor-beta in adipose tissue from obese mice. Mol Med 1997; 3:37-48.
    • (1997) Mol Med , vol.3 , pp. 37-48
    • Samad, F.1    Yamamoto, K.2    Pandey, M.3    Loskutoff, D.J.4
  • 45
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid
    • Fried SK, Bunkin DA, Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 1998; 83:847-50.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 46
    • 77952536377 scopus 로고    scopus 로고
    • Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function
    • Neveu WA, Allard JL, Raymond DM et al. Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function. Respir Res 2010; 11:28.
    • (2010) Respir Res , vol.11 , pp. 28
    • Neveu, W.A.1    Allard, J.L.2    Raymond, D.M.3
  • 47
    • 33846198799 scopus 로고    scopus 로고
    • Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle
    • Ammit AJ, Moir LM, Oliver BG et al. Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2007; 292:L199-206.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Ammit, A.J.1    Moir, L.M.2    Oliver, B.G.3
  • 48
    • 20144375594 scopus 로고    scopus 로고
    • The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo
    • Doganci A, Eigenbrod T, Krug N et al. The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo. J Clin Invest 2005; 115:313-25.
    • (2005) J Clin Invest , vol.115 , pp. 313-325
    • Doganci, A.1    Eigenbrod, T.2    Krug, N.3
  • 49
    • 0036398446 scopus 로고    scopus 로고
    • The IL-1 family and inflammatory diseases
    • Dinarello CA. The IL-1 family and inflammatory diseases. Clin Exp Rheumatol 2002; 20:S1-13.
    • (2002) Clin Exp Rheumatol , vol.20
    • Dinarello, C.A.1
  • 50
    • 0027054882 scopus 로고
    • Eosinophil transendothelial migration induced by cytokines. I. Role of endothelial and eosinophil adhesion molecules in IL-1 beta-induced transendothelial migration
    • Ebisawa M, Bochner BS, Georas SN, Schleimer RP. Eosinophil transendothelial migration induced by cytokines. I. Role of endothelial and eosinophil adhesion molecules in IL-1 beta-induced transendothelial migration. J Immunol 1992; 149:4021-8.
    • (1992) J Immunol , vol.149 , pp. 4021-4028
    • Ebisawa, M.1    Bochner, B.S.2    Georas, S.N.3    Schleimer, R.P.4
  • 51
    • 6444237318 scopus 로고    scopus 로고
    • Role and regulation of interleukin-1 molecules in pro-asthmatic sensitised airway smooth muscle
    • Whelan R, Kim C, Chen M, Leiter J, Grunstein MM, Hakonarson H. Role and regulation of interleukin-1 molecules in pro-asthmatic sensitised airway smooth muscle. Eur Respir J 2004; 24:559-67.
    • (2004) Eur Respir J , vol.24 , pp. 559-567
    • Whelan, R.1    Kim, C.2    Chen, M.3    Leiter, J.4    Grunstein, M.M.5    Hakonarson, H.6
  • 52
    • 0028989599 scopus 로고
    • TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation
    • Lukacs NW, Strieter RM, Chensue SW, Widmer M, Kunkel SL. TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation. J Immunol 1995; 154:5411-7.
    • (1995) J Immunol , vol.154 , pp. 5411-5417
    • Lukacs, N.W.1    Strieter, R.M.2    Chensue, S.W.3    Widmer, M.4    Kunkel, S.L.5
  • 53
    • 0038456928 scopus 로고
    • Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor
    • Broudy VC, Kaushansky K, Segal GM, Harlan JM, Adamson JW. Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor. Proc Natl Acad Sci U S A 1986; 83:7467-71.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 7467-7471
    • Broudy, V.C.1    Kaushansky, K.2    Segal, G.M.3    Harlan, J.M.4    Adamson, J.W.5
  • 54
    • 0023041563 scopus 로고
    • Recombinant human TNF induces production of granulocyte-monocyte colony-stimulating factor
    • Munker R, Gasson J, Ogawa M, Koeffler HP. Recombinant human TNF induces production of granulocyte-monocyte colony-stimulating factor. Nature 1986; 323:79-82.
    • (1986) Nature , vol.323 , pp. 79-82
    • Munker, R.1    Gasson, J.2    Ogawa, M.3    Koeffler, H.P.4
  • 55
    • 0023272408 scopus 로고
    • Recombinant human TNF alpha stimulates production of granulocyte colony-stimulating factor
    • Koeffler HP, Gasson J, Ranyard J, Souza L, Shepard M, Munker R. Recombinant human TNF alpha stimulates production of granulocyte colony-stimulating factor. Blood 1987; 70:55-9.
    • (1987) Blood , vol.70 , pp. 55-59
    • Koeffler, H.P.1    Gasson, J.2    Ranyard, J.3    Souza, L.4    Shepard, M.5    Munker, R.6
  • 56
    • 0023851443 scopus 로고
    • Interleukin 1 induces human marrow stromal cells in long-term culture to produce granulocyte colony-stimulating factor and macrophage colony-stimulating factor
    • Fibbe WE, van Damme J, Billiau A et al. Interleukin 1 induces human marrow stromal cells in long-term culture to produce granulocyte colony-stimulating factor and macrophage colony-stimulating factor. Blood 1988; 71:430-5.
    • (1988) Blood , vol.71 , pp. 430-435
    • Fibbe, W.E.1    van Damme, J.2    Billiau, A.3
  • 57
    • 70349160768 scopus 로고    scopus 로고
    • Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling
    • Medoff BD, Okamoto Y, Leyton P et al. Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol 2009; 41:397-406.
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 397-406
    • Medoff, B.D.1    Okamoto, Y.2    Leyton, P.3
  • 58
    • 34547860034 scopus 로고    scopus 로고
    • Leptin-mediated cytokine release and migration of eosinophils: implications for immunopathophysiology of allergic inflammation
    • Wong CK, Cheung PF, Lam CW. Leptin-mediated cytokine release and migration of eosinophils: implications for immunopathophysiology of allergic inflammation. Eur J Immunol 2007; 37:2337-48.
    • (2007) Eur J Immunol , vol.37 , pp. 2337-2348
    • Wong, C.K.1    Cheung, P.F.2    Lam, C.W.3
  • 59
    • 84879791811 scopus 로고    scopus 로고
    • Serum leptin and adiponectin levels correlate with severity of allergic rhinitis
    • Hsueh KC, Lin YJ, Lin HC, Lin CY. Serum leptin and adiponectin levels correlate with severity of allergic rhinitis. Pediatr Allergy Immunol 2010; 21:e155-9.
    • (2010) Pediatr Allergy Immunol , vol.21
    • Hsueh, K.C.1    Lin, Y.J.2    Lin, H.C.3    Lin, C.Y.4
  • 61
    • 33645564998 scopus 로고    scopus 로고
    • Association between leptin and asthma in adults
    • Sood A, Ford ES, Camargo CA Jr. Association between leptin and asthma in adults. Thorax 2006; 61:300-5.
    • (2006) Thorax , vol.61 , pp. 300-305
    • Sood, A.1    Ford, E.S.2    Camargo Jr, C.A.3
  • 62
    • 79951975605 scopus 로고    scopus 로고
    • Adiposity, adipokines, and exhaled nitric oxide in healthy adults without asthma
    • Kim SH, Kim TH, Lee JS et al. Adiposity, adipokines, and exhaled nitric oxide in healthy adults without asthma. J Asthma 2011; 48:177-82.
    • (2011) J Asthma , vol.48 , pp. 177-182
    • Kim, S.H.1    Kim, T.H.2    Lee, J.S.3
  • 63
    • 79952593123 scopus 로고    scopus 로고
    • Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls
    • Holguin F, Rojas M, Brown LA, Fitzpatrick AM. Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls. J Asthma 2011; 48:217-23.
    • (2011) J Asthma , vol.48 , pp. 217-223
    • Holguin, F.1    Rojas, M.2    Brown, L.A.3    Fitzpatrick, A.M.4
  • 64
    • 77953302599 scopus 로고    scopus 로고
    • A comparison of obese and nonobese people with asthma: exploring an asthma-obesity interaction
    • Pakhale S, Doucette S, Vandemheen K et al. A comparison of obese and nonobese people with asthma: exploring an asthma-obesity interaction. Chest 2010; 137:1316-23.
    • (2010) Chest , vol.137 , pp. 1316-1323
    • Pakhale, S.1    Doucette, S.2    Vandemheen, K.3
  • 65
    • 0024396492 scopus 로고
    • Respiratory function in the morbidly obese before and after weight loss
    • Thomas PS, Cowen ER, Hulands G, Milledge JS. Respiratory function in the morbidly obese before and after weight loss. Thorax 1989; 44:382-6.
    • (1989) Thorax , vol.44 , pp. 382-386
    • Thomas, P.S.1    Cowen, E.R.2    Hulands, G.3    Milledge, J.S.4
  • 67
    • 0033728998 scopus 로고    scopus 로고
    • Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma
    • Hakala K, Stenius-Aarniala B, Sovijarvi A. Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma. Chest 2000; 118:1315-21.
    • (2000) Chest , vol.118 , pp. 1315-1321
    • Hakala, K.1    Stenius-Aarniala, B.2    Sovijarvi, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.