-
1
-
-
84964698727
-
Biological and therapeutic implication of the BRAF pathway in histiocytic disorders
-
Arceci RJ. Biological and therapeutic implication of the BRAF pathway in histiocytic disorders. Am Soc Clin Oncol Educ Book. 2014:e441-445.
-
(2014)
Am Soc Clin Oncol Educ Book
-
-
Arceci, R.J.1
-
2
-
-
77956904045
-
Recurrent BRAF mutations in Langerhans cell histiocytosis
-
Badalian-Very G, Vergilio JA, Degar BA, MacConaill LE, Brandner B, Calicchio ML, Kuo FC, Ligon AH, Stevenson KE, Kehoe SM, Garraway LA, Hahn WC, Meyerson M, et al. Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood. 2010; 116:1919-1923.
-
(2010)
Blood.
, vol.116
, pp. 1919-1923
-
-
Badalian-Very, G.1
Vergilio, J.A.2
Degar, B.A.3
MacConaill, L.E.4
Brandner, B.5
Calicchio, M.L.6
Kuo, F.C.7
Ligon, A.H.8
Stevenson, K.E.9
Kehoe, S.M.10
Garraway, L.A.11
Hahn, W.C.12
Meyerson, M.13
-
3
-
-
84905124784
-
Potential clinical implications of BRAF mutations in histiocytic proliferations
-
Bubolz AM, Weissinger SE, Stenzinger A, Arndt A, Steinestel K, Brüderlein S, Cario H, Lubatschofski A, Welke C, Anagnostopoulos I, Barth TF, Beer AJ, Möller P, et al. Potential clinical implications of BRAF mutations in histiocytic proliferations. Oncotarget. 2014; 5:4060-4070.
-
(2014)
Oncotarget.
, vol.5
, pp. 4060-4070
-
-
Bubolz, A.M.1
Weissinger, S.E.2
Stenzinger, A.3
Arndt, A.4
Steinestel, K.5
Brüderlein, S.6
Cario, H.7
Lubatschofski, A.8
Welke, C.9
Anagnostopoulos, I.10
Barth, T.F.11
Beer, A.J.12
Möller, P.13
-
4
-
-
84866596727
-
High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses
-
Haroche J, Charlotte F, Arnaud L, von Deimling A, Hélias-Rodzewicz Z, Hervier B, Cohen-Aubart F, Launay D, Lesot A, Mokhtari K, Canioni D, Galmiche L, Rose C, et al. High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses. Blood. 2012; 120:2700-2703.
-
(2012)
Blood.
, vol.120
, pp. 2700-2703
-
-
Haroche, J.1
Charlotte, F.2
Arnaud, L.3
von Deimling, A.4
Hélias-Rodzewicz, Z.5
Hervier, B.6
Cohen-Aubart, F.7
Launay, D.8
Lesot, A.9
Mokhtari, K.10
Canioni, D.11
Galmiche, L.12
Rose, C.13
-
5
-
-
84922372527
-
Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders
-
Hyman DM, Diamond EL, Vibat CR, Hassaine L, Poole JC, Patel M, Holley VR, Cabrilo G, Lu TT, Arcila ME, Chung YR, Rampal R, Lacouture ME, et al. Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders. Cancer Discov. 2015; 5:64-71.
-
(2015)
Cancer Discov.
, vol.5
, pp. 64-71
-
-
Hyman, D.M.1
Diamond, E.L.2
Vibat, C.R.3
Hassaine, L.4
Poole, J.C.5
Patel, M.6
Holley, V.R.7
Cabrilo, G.8
Lu, T.T.9
Arcila, M.E.10
Chung, Y.R.11
Rampal, R.12
Lacouture, M.E.13
-
6
-
-
84922354803
-
Reproducible and Sustained Efficacy of Targeted Therapy With Vemurafenib in Patients With BRAFV600E-Mutated Erdheim-Chester Disease
-
Haroche J, Cohen-Aubart F, Emile JF, Maksud P, Drier A, Tolédano D, Barete S, Charlotte F, Cluzel P, Donadieu J, Benameur N, Grenier PA, Besnard S, et al. Reproducible and Sustained Efficacy of Targeted Therapy With Vemurafenib in Patients With BRAFV600E-Mutated Erdheim-Chester Disease. J Clin Oncol. 2015; 33:411-418.
-
(2015)
J Clin Oncol.
, vol.33
, pp. 411-418
-
-
Haroche, J.1
Cohen-Aubart, F.2
Emile, J.F.3
Maksud, P.4
Drier, A.5
Tolédano, D.6
Barete, S.7
Charlotte, F.8
Cluzel, P.9
Donadieu, J.10
Benameur, N.11
Grenier, P.A.12
Besnard, S.13
-
7
-
-
84876498502
-
Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation
-
Haroche J, Cohen-Aubart F, Emile JF, Arnaud L, Maksud P, Charlotte F, Cluzel P, Drier A, Hervier B, Benameur N, Besnard S, Donadieu J, Amoura Z. Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation. Blood. 2013; 121:1495-1500.
-
(2013)
Blood.
, vol.121
, pp. 1495-1500
-
-
Haroche, J.1
Cohen-Aubart, F.2
Emile, J.F.3
Arnaud, L.4
Maksud, P.5
Charlotte, F.6
Cluzel, P.7
Drier, A.8
Hervier, B.9
Benameur, N.10
Besnard, S.11
Donadieu, J.12
Amoura, Z.13
-
8
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014; 515:563-567.
-
(2014)
Nature.
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
Fine, G.D.4
Hamid, O.5
Gordon, M.S.6
Sosman, J.A.7
McDermott, D.F.8
Powderly, J.D.9
Gettinger, S.N.10
Kohrt, H.E.11
Horn, L.12
Lawrence, D.P.13
-
9
-
-
84904024273
-
Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
-
Taube JM, Klein A, Brahmer JR, Xu H, Pan X, Kim JH, Chen L, Pardoll DM, Topalian SL, Anders RA. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res. 2014; 20:5064-5074.
-
(2014)
Clin Cancer Res.
, vol.20
, pp. 5064-5074
-
-
Taube, J.M.1
Klein, A.2
Brahmer, J.R.3
Xu, H.4
Pan, X.5
Kim, J.H.6
Chen, L.7
Pardoll, D.M.8
Topalian, S.L.9
Anders, R.A.10
-
10
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012; 366:2443-2454.
-
(2012)
N Engl J Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
Leming, P.D.11
Spigel, D.R.12
Antonia, S.J.13
-
12
-
-
84919385463
-
Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type
-
Gatalica Z, Snyder C, Maney T, Ghazalpour A, Holterman DA, Xiao N, Overberg P, Rose I, Basu GD, Vranic S, Lynch HT, Von Hoff DD, Hamid O. Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type. Cancer Epidemiol Biomarkers Prev. 2014; 23:2965-2970.
-
(2014)
Cancer Epidemiol Biomarkers Prev.
, vol.23
, pp. 2965-2970
-
-
Gatalica, Z.1
Snyder, C.2
Maney, T.3
Ghazalpour, A.4
Holterman, D.A.5
Xiao, N.6
Overberg, P.7
Rose, I.8
Basu, G.D.9
Vranic, S.10
Lynch, H.T.11
Von Hoff, D.D.12
Hamid, O.13
-
13
-
-
84940447406
-
BRAF V600E mutationspecific antibody: A review
-
Feb 7, [Epub ahead of print]
-
Ritterhouse LL, Barletta JA. BRAF V600E mutationspecific antibody: A review. Semin Diagn Pathol. 2015 Feb 7. pii: S0740-2570(15)00011-8. doi: 10.1053/j. semdp.2015.02.010. [Epub ahead of print]
-
(2015)
Semin Diagn Pathol
-
-
Ritterhouse, L.L.1
Barletta, J.A.2
-
14
-
-
84894167130
-
Immunohistochemical detection of BRAF V600E mutant protein using the VE1 antibody in colorectal carcinoma is highly concordant with molecular testing but requires rigorous antibody optimization
-
Kuan SF, Navina S, Cressman KL, Pai RK. Immunohistochemical detection of BRAF V600E mutant protein using the VE1 antibody in colorectal carcinoma is highly concordant with molecular testing but requires rigorous antibody optimization. Hum Pathol 2014; 45:464-472.
-
(2014)
Hum Pathol
, vol.45
, pp. 464-472
-
-
Kuan, S.F.1
Navina, S.2
Cressman, K.L.3
Pai, R.K.4
-
15
-
-
84909609809
-
Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis
-
Chakraborty R, Hampton OA, Shen X, Simko SJ, Shih A, Abhyankar H, Lim KP, Covington KR, Trevino L, Dewal N, Muzny DM, Doddapaneni H, Hu J, et al. Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis. Blood. 2014; 124:3007-3015.
-
(2014)
Blood.
, vol.124
, pp. 3007-3015
-
-
Chakraborty, R.1
Hampton, O.A.2
Shen, X.3
Simko, S.J.4
Shih, A.5
Abhyankar, H.6
Lim, K.P.7
Covington, K.R.8
Trevino, L.9
Dewal, N.10
Muzny, D.M.11
Doddapaneni, H.12
Hu, J.13
-
16
-
-
84886878689
-
Detection of an NRAS mutation in Erdheim-Chester disease
-
Diamond EL, Abdel-Wahab O, Pentsova E, Borsu L, Chiu A, Teruya-Feldstein J, Hyman DM, Rosenblum M. Detection of an NRAS mutation in Erdheim-Chester disease. Blood. 2013; 122:1089-1091.
-
(2013)
Blood.
, vol.122
, pp. 1089-1091
-
-
Diamond, E.L.1
Abdel-Wahab, O.2
Pentsova, E.3
Borsu, L.4
Chiu, A.5
Teruya-Feldstein, J.6
Hyman, D.M.7
Rosenblum, M.8
-
17
-
-
84909643356
-
Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease
-
Emile JF, Diamond EL, Hélias-Rodzewicz Z, Cohen-Aubart F, Charlotte F, Hyman DM, Kim E, Rampal R, Patel M, Ganzel C, Aumann S, Faucher G, Le Gall C, et al. Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease. Blood. 2014; 124:3016-3019.
-
(2014)
Blood.
, vol.124
, pp. 3016-3019
-
-
Emile, J.F.1
Diamond, E.L.2
Hélias-Rodzewicz, Z.3
Cohen-Aubart, F.4
Charlotte, F.5
Hyman, D.M.6
Kim, E.7
Rampal, R.8
Patel, M.9
Ganzel, C.10
Aumann, S.11
Faucher, G.12
Le Gall, C.13
-
18
-
-
84904320952
-
Frequent detection of BRAF(V600E) mutations in histiocytic and dendritic cell neoplasms
-
Go H, Jeon YK, Huh J, Choi SJ, Choi YD, Cha HJ, Kim HJ, Park G, Min S, Kim JE. Frequent detection of BRAF(V600E) mutations in histiocytic and dendritic cell neoplasms. Histopathology. 2014; 65:261-272.
-
(2014)
Histopathology.
, vol.65
, pp. 261-272
-
-
Go, H.1
Jeon, Y.K.2
Huh, J.3
Choi, S.J.4
Choi, Y.D.5
Cha, H.J.6
Kim, H.J.7
Park, G.8
Min, S.9
Kim, J.E.10
-
19
-
-
33646358695
-
The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans
-
Carrasco DR, Fenton T, Sukhdeo K, Protopopova M, Enos M, You MJ, Di Vizio D, Nogueira C, Stommel J, Pinkus GS, Fletcher C, Hornick JL, Cavenee WK, et al. The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell. 2006; 9:379-390.
-
(2006)
Cancer Cell.
, vol.9
, pp. 379-390
-
-
Carrasco, D.R.1
Fenton, T.2
Sukhdeo, K.3
Protopopova, M.4
Enos, M.5
You, M.J.6
Di Vizio, D.7
Nogueira, C.8
Stommel, J.9
Pinkus, G.S.10
Fletcher, C.11
Hornick, J.L.12
Cavenee, W.K.13
-
20
-
-
84920031397
-
Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases
-
Gatalica Z, Millis SZ, Vranic S, Bender R, Basu GD, Voss A, Von Hoff DD. Comprehensive tumor profiling identifies numerous biomarkers of drug response in cancers of unknown primary site: Analysis of 1806 cases. Oncotarget. 2014; 5:12440-12447.
-
(2014)
Oncotarget.
, vol.5
, pp. 12440-12447
-
-
Gatalica, Z.1
Millis, S.Z.2
Vranic, S.3
Bender, R.4
Basu, G.D.5
Voss, A.6
Von Hoff, D.D.7
-
21
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
-
Ansell SM, Lesokhin AM, Borrello I, Halwani A, Scott EC, Gutierrez M, Schuster SJ, Millenson MM, Cattry D, Freeman GJ, Rodig SJ, Chapuy B, Ligon AH, et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med. 2015; 372:311-319.
-
(2015)
N Engl J Med.
, vol.372
, pp. 311-319
-
-
Ansell, S.M.1
Lesokhin, A.M.2
Borrello, I.3
Halwani, A.4
Scott, E.C.5
Gutierrez, M.6
Schuster, S.J.7
Millenson, M.M.8
Cattry, D.9
Freeman, G.J.10
Rodig, S.J.11
Chapuy, B.12
Ligon, A.H.13
-
22
-
-
84879866976
-
PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies
-
Chen BJ, Chapuy B, Ouyang J, Sun HH, Roemer MG, Xu ML, Yu H, Fletcher CD, Freeman GJ, Shipp MA, Rodig SJ. PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies. Clin Cancer Res. 2013; 19:3462-3473.
-
(2013)
Clin Cancer Res.
, vol.19
, pp. 3462-3473
-
-
Chen, B.J.1
Chapuy, B.2
Ouyang, J.3
Sun, H.H.4
Roemer, M.G.5
Xu, M.L.6
Yu, H.7
Fletcher, C.D.8
Freeman, G.J.9
Shipp, M.A.10
Rodig, S.J.11
-
23
-
-
77749328948
-
Distribution of PD-1+ lymphocytes in reactive lymphadenopathies
-
Muenst S, Dirnhofer S, Tzankov A. Distribution of PD-1+ lymphocytes in reactive lymphadenopathies. Pathobiology. 2010; 77:24-27.
-
(2010)
Pathobiology.
, vol.77
, pp. 24-27
-
-
Muenst, S.1
Dirnhofer, S.2
Tzankov, A.3
|