-
1
-
-
84881296056
-
Cancer of unknown primary site: improved patient management with molecular and immunohistochemical diagnosis
-
Greco FA. Cancer of unknown primary site: improved patient management with molecular and immunohistochemical diagnosis. Am Soc Clin Oncol Educ Book. 2013; 175-181.
-
(2013)
Am Soc Clin Oncol Educ Book
, pp. 175-181
-
-
Greco, F.A.1
-
2
-
-
84859625307
-
Cancer of unknown primary site
-
Pavlidis N, Pentheroudakis G. Cancer of unknown primary site. Lancet. 2012; 379:1428-1435.
-
(2012)
Lancet
, vol.379
, pp. 1428-1435
-
-
Pavlidis, N.1
Pentheroudakis, G.2
-
3
-
-
80052724384
-
Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
Fizazi K, Greco FA, Pavlidis N, et al. Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2011; 22:vi64-68.
-
(2011)
Ann Oncol
, vol.22
, pp. vi64-vi68
-
-
Fizazi, K.1
Greco, F.A.2
Pavlidis, N.3
-
4
-
-
84903965503
-
Occult primary, version 3.2014
-
Ettinger DS, Handorf CR, Agulnik M, et al. Occult primary, version 3.2014. J Natl Compr Canc Netw. 2014; 12:969-974.
-
(2014)
J Natl Compr Canc Netw
, vol.12
, pp. 969-974
-
-
Ettinger, D.S.1
Handorf, C.R.2
Agulnik, M.3
-
5
-
-
58549096556
-
Treatment for patients with unknown primary carcinoma and unfavorable prognostic factors
-
Greco FA, Pavlidis N. Treatment for patients with unknown primary carcinoma and unfavorable prognostic factors. Semin Oncol. 2009; 36:65-74.
-
(2009)
Semin Oncol
, vol.36
, pp. 65-74
-
-
Greco, F.A.1
Pavlidis, N.2
-
6
-
-
70350361222
-
Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: multiple-treatments meta-analysis
-
Golfinopoulos V, Pentheroudakis G, Salanti G, et al. Comparative survival with diverse chemotherapy regimens for cancer of unknown primary site: multiple-treatments meta-analysis. Cancer Treat Rev. 2009; 35:570-573.
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 570-573
-
-
Golfinopoulos, V.1
Pentheroudakis, G.2
Salanti, G.3
-
7
-
-
84881256279
-
New strategies for carcinoma of unknown primary: the role of tissue-of-origin molecular profiling
-
Varadhachary G. New strategies for carcinoma of unknown primary: the role of tissue-of-origin molecular profiling. Clin Cancer Res. 2013; 19:4027-4033.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4027-4033
-
-
Varadhachary, G.1
-
8
-
-
52449084470
-
Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation
-
Varadhachary GR, Talantov D, Raber MN, et al. Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation. J Clin Oncol. 2008; 26:4442-4448.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4442-4448
-
-
Varadhachary, G.R.1
Talantov, D.2
Raber, M.N.3
-
9
-
-
84880473776
-
Personalizing oncology: perspectives and prospects
-
Mendelsohn J. Personalizing oncology: perspectives and prospects. J Clin Oncol. 2013; 31:1904-1911.
-
(2013)
J Clin Oncol
, vol.31
, pp. 1904-1911
-
-
Mendelsohn, J.1
-
10
-
-
84869223443
-
Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative
-
Tsimberidou AM, Iskander NG, Hong DS, et al. Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative. Clin Cancer Res. 2012; 18:6373-6383.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6373-6383
-
-
Tsimberidou, A.M.1
Iskander, N.G.2
Hong, D.S.3
-
11
-
-
84891863428
-
Integrating molecular profiling into cancer treatment decision, making: experience with over 35,000 cases
-
11001
-
Gatalica Z, Millis S, Chen W, Basu GD, Wen W, Paul L, Bender RP, Von Hoff DD. Integrating molecular profiling into cancer treatment decision, making: experience with over 35,000 cases. J Clin Oncol. 2013;31(suppl; abstr 11001).
-
(2013)
J Clin Oncol
, vol.31
-
-
Gatalica, Z.1
Millis, S.2
Chen, W.3
Basu, G.D.4
Wen, W.5
Paul, L.6
Bender, R.P.7
Von Hoff, D.D.8
-
12
-
-
84872567958
-
Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients with carcinoma of unknown primary site: a prospective trial of the Sarah Cannon research institute
-
Hainsworth JD, Rubin MS, Spigel DR, et al. Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients with carcinoma of unknown primary site: a prospective trial of the Sarah Cannon research institute. J Clin Oncol. 2013; 31:217-223.
-
(2013)
J Clin Oncol
, vol.31
, pp. 217-223
-
-
Hainsworth, J.D.1
Rubin, M.S.2
Spigel, D.R.3
-
14
-
-
84902505841
-
Successful imatinib therapy for neuroendocrine carcinoma with activating Kit mutation: a case study
-
Perkins J, Boland P, Cohen SJ, et al. Successful imatinib therapy for neuroendocrine carcinoma with activating Kit mutation: a case study. J Natl Compr Canc Netw. 2014; 12:847-852.
-
(2014)
J Natl Compr Canc Netw
, vol.12
, pp. 847-852
-
-
Perkins, J.1
Boland, P.2
Cohen, S.J.3
-
15
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
Wan PT, Garnett MJ, Roe SM, et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004; 116:855-867.
-
(2004)
Cell
, vol.116
, pp. 855-867
-
-
Wan, P.T.1
Garnett, M.J.2
Roe, S.M.3
-
16
-
-
84857923270
-
GNAQ and GNA11 mutations in melanocytomas of the central nervous system
-
Murali R, Wiesner T, Rosenblum MK, Bastian BC. GNAQ and GNA11 mutations in melanocytomas of the central nervous system. Acta Neuropathol. 2012; 123:457-459.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 457-459
-
-
Murali, R.1
Wiesner, T.2
Rosenblum, M.K.3
Bastian, B.C.4
-
17
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth C, McLellan MD, Vandin F, et al. Mutational landscape and significance across 12 major cancer types. Nature. 2013; 502:333-339.
-
(2013)
Nature
, vol.502
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
-
18
-
-
84879488821
-
Molecular profiling for druggable genetic abnormalities in carcinoma of unknown primary
-
Tan DS, Montoya J, Ng QS, et al. Molecular profiling for druggable genetic abnormalities in carcinoma of unknown primary. J Clin Oncol. 2013; 31:e237-239.
-
(2013)
J Clin Oncol
, vol.31
-
-
Tan, D.S.1
Montoya, J.2
Ng, Q.S.3
-
19
-
-
84867623031
-
Cancer of unknown primary site with epidermal growth factor receptor mutation for which gefitinib proved effective
-
Yamada T, Ohtsubo K, Ishikawa D, et al. Cancer of unknown primary site with epidermal growth factor receptor mutation for which gefitinib proved effective. Gan To Kagaku Ryoho. 2012; 39:1291-1294.
-
(2012)
Gan To Kagaku Ryoho
, vol.39
, pp. 1291-1294
-
-
Yamada, T.1
Ohtsubo, K.2
Ishikawa, D.3
-
20
-
-
84887555902
-
Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary
-
Tothill RW, Li J, Mileshkin L, et al. Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary. J Pathol. 2013; 231:413-423.
-
(2013)
J Pathol
, vol.231
, pp. 413-423
-
-
Tothill, R.W.1
Li, J.2
Mileshkin, L.3
-
21
-
-
84876480383
-
Exploring the biology of cancer of unknown primary: breakthroughs and drawbacks
-
Kamposioras K, Pentheroudakis G, Pavlidis N. Exploring the biology of cancer of unknown primary: breakthroughs and drawbacks. Eur J Clin Invest. 2013; 43:491-500.
-
(2013)
Eur J Clin Invest
, vol.43
, pp. 491-500
-
-
Kamposioras, K.1
Pentheroudakis, G.2
Pavlidis, N.3
-
22
-
-
84911991900
-
Mutational profiling of the RAS, PI3K, MET and b-catenin pathways in cancer of unknown primary: a retrospective study of the Hellenic Cooperative Oncology Group
-
Pentheroudakis G, Kotteas EA, Kotoula V, et al. Mutational profiling of the RAS, PI3K, MET and b-catenin pathways in cancer of unknown primary: a retrospective study of the Hellenic Cooperative Oncology Group. Clin Exp Metastasis 2014.
-
(2014)
Clin Exp Metastasis
-
-
Pentheroudakis, G.1
Kotteas, E.A.2
Kotoula, V.3
-
23
-
-
84863230465
-
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
-
Prahallad A, Sun C, Huang S, et al. Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature. 2012; 483:100-103.
-
(2012)
Nature
, vol.483
, pp. 100-103
-
-
Prahallad, A.1
Sun, C.2
Huang, S.3
-
24
-
-
84880100858
-
Off-label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer
-
Al-Marrawi MY, Saroya BS, Brennan MC, et al. Off-label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer. Cancer Biol Ther. 2013; 14:703-710.
-
(2013)
Cancer Biol Ther
, vol.14
, pp. 703-710
-
-
Al-Marrawi, M.Y.1
Saroya, B.S.2
Brennan, M.C.3
-
25
-
-
84874650275
-
Development of PI3K inhibitors: lessons learned from early clinical trials
-
Rodon J, Dienstmann R, Serra V, Tabernero J. Development of PI3K inhibitors: lessons learned from early clinical trials. Nat Rev Clin Oncol. 2013; 10:143-153.
-
(2013)
Nat Rev Clin Oncol
, vol.10
, pp. 143-153
-
-
Rodon, J.1
Dienstmann, R.2
Serra, V.3
Tabernero, J.4
-
26
-
-
84945990416
-
Targeting the PI3K/AKT/ mTOR pathway: biomarkers of success and tribulation
-
Owonikoko TK, Khuri FR. Targeting the PI3K/AKT/ mTOR pathway: biomarkers of success and tribulation. Am Soc Clin Oncol Educ Book 2013.
-
(2013)
Am Soc Clin Oncol Educ Book
-
-
Owonikoko, T.K.1
Khuri, F.R.2
-
27
-
-
84859874162
-
The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer
-
Shimizu T, Tolcher AW, Papadopoulos KP, et al. The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer. Clin Cancer Res. 2012; 18: 2316-2325.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2316-2325
-
-
Shimizu, T.1
Tolcher, A.W.2
Papadopoulos, K.P.3
-
28
-
-
84874830056
-
Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types
-
Ascierto PA, Kalos M, Schaer DA, et al. Biomarkers for immunostimulatory monoclonal antibodies in combination strategies for melanoma and other tumor types. Clin Cancer Res. 2013; 19:1009-1020.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1009-1020
-
-
Ascierto, P.A.1
Kalos, M.2
Schaer, D.A.3
-
29
-
-
84919385463
-
Programmed cell death (PD-1) and its ligand (PD-L1) expression in common cancers and their correlation with molecular cancer type
-
in press.
-
Gatalica Z, Snydder C, Maney T, Ghazalpour A, Holterman DA, Xiao N, Overberg P, Rose I, Basu GD, Vranic S, Lynch HT, Von Hoff DD, Hamid O. Programmed cell death (PD-1) and its ligand (PD-L1) expression in common cancers and their correlation with molecular cancer type. Cancer Epidemiol Biomarkers Prev 2014, in press.
-
(2014)
Cancer Epidemiol Biomarkers Prev
-
-
Gatalica, Z.1
Snydder, C.2
Maney, T.3
Ghazalpour, A.4
Holterman, D.A.5
Xiao, N.6
Overberg, P.7
Rose, I.8
Basu, G.D.9
Vranic, S.10
Lynch, H.T.11
Von Hoff, D.D.12
Hamid, O.13
-
30
-
-
79952590347
-
The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?
-
Lillie EO, Patay B, Diamant J, et al. The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?. Per Med. 2011; 8:161-173.
-
(2011)
Per Med
, vol.8
, pp. 161-173
-
-
Lillie, E.O.1
Patay, B.2
Diamant, J.3
-
31
-
-
84875181563
-
ERCC1 isoform expression and DNA repair in non-small-cell lung cancer
-
Friboulet L, Olaussen KA, Pignon JP, et al. ERCC1 isoform expression and DNA repair in non-small-cell lung cancer. N Engl J Med. 2013; 368:1101-1110.
-
(2013)
N Engl J Med
, vol.368
, pp. 1101-1110
-
-
Friboulet, L.1
Olaussen, K.A.2
Pignon, J.P.3
-
32
-
-
84920370011
-
Theranostic molecular profiling of infiltrating urothelial carcinoma of the bladder
-
Aug 1
-
Millis S, Bryant D, Basu G, Bender R, Vranic S, Gatalica Z, Vogelzang NJ. Theranostic molecular profiling of infiltrating urothelial carcinoma of the bladder. Clinical Genitourinary Cancer 2014 Aug 1, Doi: 10.1016/j.clgc.2014.07.010.
-
(2014)
Clinical Genitourinary Cancer
-
-
Millis, S.1
Bryant, D.2
Basu, G.3
Bender, R.4
Vranic, S.5
Gatalica, Z.6
Vogelzang, N.J.7
-
33
-
-
85038642742
-
-
NCCNCompendium: http://www.nccn.org/professionals/drug_ compendium/MatrixGenerator/Matrix.aspx?DiseaseID=102.
-
-
-
|