The effect of Midazolam and Propranolol on fear memory reconsolidation in ethanol-withdrawn rats: Influence of D-cycloserine

International Journal of Neuropsychopharmacology

Volumn 18, Issue 4, 2014, Pages 1-11

  Ortiz, Vanesa ^a   Giachero, Marcelo ^a   Espejo, Pablo Javier ^a   Molina, Víctor Alejandro ^a   Martijena, Irene Delia ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Ethanol withdrawal; Fear memory reconsolidation; GABA A receptor; Midazolam; Propranolol

Indexed keywords

ALCOHOL; CYCLOSERINE; MIDAZOLAM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROPRANOLOL; 4 AMINOBUTYRIC ACID A RECEPTOR; AMINO ACID RECEPTOR AFFECTING AGENT; ANXIOLYTIC AGENT; CENTRAL DEPRESSANT AGENT; GABRA1 PROTEIN, RAT;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ARTICLE; BASOLATERAL AMYGDALA; CLINICAL EXAMINATION; CONTROLLED STUDY; DRUG EFFECT; FEAR; FEAR MEMORY RECONSOLIDATION; MALE; MEMORY CONSOLIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; AGONISTS; AMYGDALOID NUCLEUS; ANIMAL; CONDITIONING; DISEASE MODEL; DRUG EFFECTS; MEMORY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION; SUBSTANCE WITHDRAWAL SYNDROME; WISTAR RAT;

AMYGDALA; ANIMALS; ANTI-ANXIETY AGENTS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONDITIONING (PSYCHOLOGY); CYCLOSERINE; DISEASE MODELS, ANIMAL; ETHANOL; EXCITATORY AMINO ACID AGENTS; FEAR; MALE; MEMORY; MIDAZOLAM; PROPRANOLOL; RANDOM ALLOCATION; RATS, WISTAR; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84939201615     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyu082     Document Type: Article

References (55)

1. Alberini, CM (2005) Mechanisms of memory stabilization: are consolidation and reconsolidation similar or distinct processes? Trends Neurosci 28(1):51-56.
2. Banerjee, SP, Sharma, VK, Khanna, JM (1978) Alterations in betaadrenergic receptor binding during ethanol withdrawal. Nature 276(5686):407-409.
3. Becker, HC (2012) Effects of alcohol dependence and withdrawal on stress responsiveness and alcohol consumption. Alcohol Res 34(4):448-458.
4. Ben Mamou, C, Gamache, K, Nader, K (2006) NMDA receptors are critical for unleashing consolidated auditory fear memories. Nat Neurosci 9(10):1237-1239.
5. Bertotto, ME, Bustos, SG, Molina, VA, Martijena, ID (2006) Influence of ethanol withdrawal on fear memory: effect of D-cycloserine. Neuroscience 142(4):979-990.
6. Bertotto, ME, Bussolino, DF, Molina, VA, Martijena, ID (2010) Increased voluntary ethanol consumption and c-Fos expression in selected brain areas induced by fear memory retrieval in ethanol withdrawn rats. Eur Neuropsychopharmacol 20(8):568-581.
7. Bertotto, ME, Maldonado, NM, Bignante, EA, Gorosito, SV, Cambiasso, MJ, Molina, VA, Martijena, ID (2011) ERK activation in the amygdala and hippocampus induced by fear conditioning in ethanol withdrawn rats: modulation by MK-801. Eur Neuropsychopharmacol 21(12):892-904.
8. Blanchard, RJ, Blanchard, DC (1969) Crouching as an index of fear. J Comp Physiol Psychol 67(3):370-375.
9. Boudreau, AC, Milovanovic, M, Conrad, KL, Nelson, C, Ferrario, CR, Wolf, ME (2012) A protein cross-linking assay for measuring cell surface expression of glutamate receptor subunits in the rodent brain after in vivo treatments. Curr Protoc Neurosci. Chapter 5: Unit 5 30 31-19.
10. Bustos, SG, Maldonado, H, Molina, VA (2006) Midazolam disrupts fear memory reconsolidation. Neuroscience 139(3):831-842.
11. Bustos, SG, Giachero, M, Maldonado, H, Molina, VA (2010) Previous stress attenuates the susceptibility to Midazolam's disruptive effect on fear memory reconsolidation: influence of pre-reactivation D-cycloserine administration. Neuropsychopharmacology 35(5):1097-1108.
12. Cagetti, E, Liang, J, Spigelman, I, Olsen, RW (2003) Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Mol Pharmacol 63(1):53-64.
13. Cain, CK, Blouin, AM, Barad, M (2004) Adrenergic transmission facilitates extinction of conditional fear in mice. Learn Mem 11(2):179-187.
14. Debiec, J, LeDoux, JE (2004) Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala. Neuroscience 129(2):267-272.
15. Diaz, MR, Christian, DT, Anderson, NJ, McCool, BA (2011) Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses. J Pharm Exp Ther 337(1):162-170.
16. Dudai, Y (2006) Reconsolidation: the advantage of being refocused. Curr Opin Neurobiol 16(2):174-178.
17. Fendt, M (2001) Injections of the NMDA receptor antagonist aminophosphonopentanoic acid into the lateral nucleus of the amygdala block the expression of fear-potentiated startle and freezing. J Neurosci 21(11):4111-4115.
18. Floyd, DW, Friedman, DP, Daunais, JB, Pierre, PJ, Grant, KA, McCool, BA (2004) Long-term ethanol self-administration by cynomolgus macaques alters the pharmacology and expression of GABAA receptors in basolateral amygdala. J Pharm Exp Ther 311(3):1071-1079.
19. Giachero, M, Bustos, SG, Calfa, G, Molina, VA (2013) A BDNF sensitive mechanism is involved in the fear memory resulting from the interaction between stress and the retrieval of an established trace. Learn Mem 20(5):245-255.
20. Gilpin, NW, Koob, GF (2010) Effects of beta-adrenoceptor antagonists on alcohol drinking by alcohol-dependent rats. Psychopharmacology (Berl) 212(3):431-439.
21. Heilig, M, Egli, M, Crabbe, JC, Becker, HC (2010) Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? Addict Biol 15(2):169-184.
22. Heldt, SA, Ressler, KJ (2007) Training-induced changes in the expression of GABAA-associated genes in the amygdala after the acquisition and extinction of Pavlovian fear. Eur J Neurosci 26(12):3631-3644.
23. Holmes, A, Fitzgerald, PJ, MacPherson, KP, DeBrouse, L, Colacicco, G, Flynn, SM, Masneuf, S, Pleil, KE, Li, C, Marcinkiewcz, CA, Kash, TL, Gunduz-Cinar, O, Camp, M (2012) Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding. Nat Neurosci 15(10):1359-1361.
24. Isoardi, NA, Bertotto, ME, Martijena, ID, Molina, VA, Carrer, HF (2007) Lack of feedback inhibition on rat basolateral amygdala following stress or withdrawal from sedative-hypnotic drugs. Eur J Neurosci 26(4):1036-1044.
25. Jarome, TJ, Werner, CT, Kwapis, JL, Helmstetter, FJ (2011) Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala. PLOS ONE 6(9):e24349.
26. Kindt, M, Soeter, M, Vervliet, B (2009) Beyond extinction: erasing human fear responses and preventing the return of fear. Nat Neurosci 12(3):256-258.
27. Koob, GF (2008) A role for brain stress systems in addiction. Neuron 59(1):11-34.
28. Koob, GF, Le Moal, M (2001) Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24(2):97-129.
29. Krystal, JH, Petrakis, IL, Mason, G, Trevisan, L, D'Souza, DC (2003) N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol Ther 99(1):79-94.
30. Kuriyama, K, Muramatsu, M, Aiso, M, Ueno, E (1981) Alteration in beta-adrenergic receptor binding in brain, lung and heart during morphine and alcohol dependence and withdrawal. Neuropharmacology 20(7):659-666.
31. Lee, JL, Milton, AL, Everitt, BJ (2006) Reconsolidation and extinction of conditioned fear: inhibition and potentiation. J Neurosci 26(39):10051-10056.
32. Lee, SH, Choi, JH, Lee, N, Lee, HR, Kim, JI, Yu, NK, Choi, SL, Kim, H, Kaang, BK (2008) Synaptic protein degradation underlies destabilization of retrieved fear memory. Science 319(5867):1253-1256.
33. Makkar, SR, Zhang, SQ, Cranney, J (2010) Behavioral and neural analysis of GABA in the acquisition, consolidation, reconsolidation, and extinction of fear memory. Neuropsychopharmacology 35(8):1625-1652.
34. Mao, SC, Lin, HC, Gean, PW (2008) Augmentation of fear extinction by D-cycloserine is blocked by proteasome inhibitors. Neuropsychopharmacology 33(13):3085-3095.
35. Markou, A, Kosten, TR, Koob, GF (1998) Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology 18(3):135-174.
36. McCool, BA, Christian, DT, Diaz, MR, Lack, AK (2010) Glutamate plasticity in the drunken amygdala: the making of an anxious synapse. Int Rev Neurobiol 91:205-233.
37. McDonald, AJ, Mascagni, F (2004) Parvalbumin-containing interneurons in the basolateral amygdala express high levels of the alpha1 subunit of the GABAA receptor. J Comp Neurol 473(1):137-146.
38. Mohler, H, Fritschy, JM, Rudolph, U (2002) A new benzodiazepine pharmacology. J Pharm Exp Ther 300(1):2-8.
39. Muravieva, EV, Alberini, CM (2010) Limited efficacy of propranolol on the reconsolidation of fear memories. Learn Mem 17(6):306-313.
40. Nader, K, Schafe, GE, Le Doux, JE (2000) Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406(6797):722-726.
41. Papadeas, S, Grobin, AC, Morrow, AL (2001) Chronic ethanol consumption differentially alters GABA(A) receptor alpha1 and alpha4 subunit peptide expression and GABA(A) receptormediated 36 Cl(-) uptake in mesocorticolimbic regions of rat brain. Alcohol Clin Exp Res 25(9):1270-1275.
42. Paxinos G, Watson C (2009) The rat brain in stereotaxic coordinates: 6th edition. San Diego, CA: Academic Press.
43. Rimondini, R, Arlinde, C, Sommer, W, Heilig, M (2002) Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. FASEB J 16(1):27-35.
44. Rodriguez-Romaguera, J, Sotres-Bayon, F, Mueller, D, Quirk, GJ (2009) Systemic propranolol acts centrally to reduce conditioned fear in rats without impairing extinction. Biol Psychiatry 65(10):887-892.
45. Saladin, ME, Gray, KM, McRae-Clark, AL, Larowe, SD, Yeatts, SD, Baker, NL, Hartwell, KJ, Brady, KT (2013) A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans. Psychopharmacology (Berl) 226(4):721-737.
46. Suryanarayanan, A, Liang, J, Meyer, EM, Lindemeyer, AK, Chandra, D, Homanics, GE, Sieghart, W, Olsen, RW, Spigelman, I (2011) Subunit compensation and plasticity of synaptic GABA(A) receptors induced by ethanol in alpha4 subunit knockout mice. Front Neurosci 5:110.
47. Suzuki, A, Josselyn, SA, Frankland, PW, Masushige, S, Silva, AJ, Kida, S (2004) Memory reconsolidation and extinction have distinct temporal and biochemical signatures. J Neurosci 24(20):4787-4795.
48. Tipps, ME, Raybuck, JD, Lattal, KM (2013) Substance abuse, memory, and post-traumatic stress disorder. Neurobiol Learn Mem. Advance online publication. doi: 10.1016/j.nlm.2013.12.002
49. Tronson, NC, Taylor, JR (2007) Molecular mechanisms of memory reconsolidation. Nat Rev Neurosci 8(4):262-275.
50. Tronson, NC, Taylor, JR (2013) Addiction: a drug-induced disorder of memory reconsolidation. Curr Opin Neurobiol 23(4):573-580.
51. Walker, DL, Ressler, KJ, Lu, KT, Davis, M (2002) Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. J Neurosci 22(6):2343-2351.
52. Wang, SH, de Oliveira Alvares, L, Nader, K (2009) Cellular and systems mechanisms of memory strength as a constraint on auditory fear reconsolidation. Nat Neurosci 12(7):905-912.
53. Wiltgen, BJ, Godsil, BP, Peng, Z, Saab, F, June, HL, Linn, ML, Cook, JM, Houser, CR, O'Dell, TJ, Homanics, GE, Fanselow, MS (2009) The alpha1 subunit of the GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala. Front Behav Neurosci 3:37.
54. Wouda, JA, Diergaarde, L, Riga, D, van Mourik, Y, Schoffelmeer, AN, De Vries, TJ (2010) Disruption of long-term alcoholrelated memory reconsolidation: role of beta-adrenoceptors and NMDA receptors. Front Behav Neurosci 4:179.
55. Zhang, S, Cranney, J (2008) The role of GABA and anxiety in the reconsolidation of conditioned fear. Behav Neurosci 122(6):1295-1305.