A Biogenesis Step Upstream of Microprocessor Controls miR-17∼92 Expression

Cell

Volumn 162, Issue 4, 2015, Pages 885-899

  Du, Peng ^a,b   Wang, Longfei ^b   Sliz, Piotr ^b   Gregory, Richard I ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; MICRORNA; MICRORNA 17; MICRORNA 17 92; MICRORNA 18A; MICRORNA 19A; MICRORNA 19B; MICRORNA 20A; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; ENDONUCLEASE; RIBONUCLEASE III;

ARTICLE; BIOGENESIS; CELL DIFFERENTIATION; CLUSTER ANALYSIS; EMBRYO; EMBRYONIC STEM CELL; EXON; FEEDBACK SYSTEM; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; INTRON; MICROPROCESSOR; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; REGULATORY RNA SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA CONFORMATION; RNA SEQUENCE; SPLICEOSOME; ANIMAL; CONFORMATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; RNA PROCESSING; SEQUENCE ALIGNMENT;

ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; EMBRYONIC STEM CELLS; ENDONUCLEASES; GENE EXPRESSION; HUMANS; MICE; MICRORNAS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RIBONUCLEASE III; RNA PROCESSING, POST-TRANSCRIPTIONAL; SEQUENCE ALIGNMENT; SPLICEOSOMES;

EID: 84939170604     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.07.008     Document Type: Article

References (45)

1. D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215 233
2. S. Bian, J. Hong, Q. Li, L. Schebelle, A. Pollock, J.L. Knauss, V. Garg, and T. Sun MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex Cell Rep. 3 2013 1398 1406
3. S. Chakraborty, S. Mehtab, A. Patwardhan, and Y. Krishnan Pri-miR-17-92a transcript folds into a tertiary structure and autoregulates its processing RNA 18 2012 1014 1028
4. H.M. Chang, R. Triboulet, J.E. Thornton, and R.I. Gregory A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway Nature 497 2013 244 248
5. S.G. Chaulk, G.L. Thede, O.A. Kent, Z. Xu, E.M. Gesner, R.A. Veldhoen, S.K. Khanna, I.S. Goping, A.M. MacMillan, J.T. Mendell, and et al. Role of pri-miRNA tertiary structure in miR-17∼92 miRNA biogenesis RNA Biol. 8 2011 1105 1114
6. S.G. Chaulk, Z. Xu, M.J. Glover, and R.P. Fahlman MicroRNA miR-92a-1 biogenesis and mRNA targeting is modulated by a tertiary contact within the miR-17∼92 microRNA cluster Nucleic Acids Res. 42 2014 5234 5244
7. C.P. Concepcion, C. Bonetti, and A. Ventura The microRNA-17-92 family of microRNA clusters in development and disease Cancer J. 18 2012 262 267
8. K. Conkrite, M. Sundby, S. Mukai, J.M. Thomson, D. Mu, S.M. Hammond, and D. MacPherson miR-17∼92 cooperates with RB pathway mutations to promote retinoblastoma Genes Dev. 25 2011 1734 1745
9. L. de Pontual, E. Yao, P. Callier, L. Faivre, V. Drouin, S. Cariou, A. Van Haeringen, D. Geneviève, A. Goldenberg, M. Oufadem, and et al. Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans Nat. Genet. 43 2011 1026 1030
10. G. Di Leva, and C.M. Croce Roles of small RNAs in tumor formation Trends Mol. Med. 16 2010 257 267
11. I. Dix, C. Russell, S.B. Yehuda, M. Kupiec, and J.D. Beggs The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae RNA 5 1999 360 368
12. Z. Dominski, X.C. Yang, and W.F. Marzluff The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing Cell 123 2005 37 48
13. R.I. Gregory, K.P. Yan, G. Amuthan, T. Chendrimada, B. Doratotaj, N. Cooch, and R. Shiekhattar The Microprocessor complex mediates the genesis of microRNAs Nature 432 2004 235 240
14. S. Guil, and J.F. Cáceres The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a Nat. Struct. Mol. Biol. 14 2007 591 596
15. M. Ha, and V.N. Kim Regulation of microRNA biogenesis Nat. Rev. Mol. Cell Biol. 15 2014 509 524
16. L. He, J.M. Thomson, M.T. Hemann, E. Hernando-Monge, D. Mu, S. Goodson, S. Powers, C. Cordon-Cardo, S.W. Lowe, G.J. Hannon, and S.M. Hammond A microRNA polycistron as a potential human oncogene Nature 435 2005 828 833
17. H.B. Houbaviy, L. Dennis, R. Jaenisch, and P.A. Sharp Characterization of a highly variable eutherian microRNA gene RNA 11 2005 1245 1257
18. N. Kataoka, M. Fujita, and M. Ohno Functional association of the Microprocessor complex with the spliceosome Mol. Cell. Biol. 29 2009 3243 3254
19. Y.K. Kim, and V.N. Kim Processing of intronic microRNAs EMBO J. 26 2007 775 783
20. A. Kyburz, A. Friedlein, H. Langen, and W. Keller Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3′ end processing and splicing Mol. Cell 23 2006 195 205
21. Y. Li, L.M. Vecchiarelli-Federico, Y.J. Li, S.E. Egan, D. Spaner, M.R. Hough, and Y. Ben-David The miR-17-92 cluster expands multipotent hematopoietic progenitors whereas imbalanced expression of its individual oncogenic miRNAs promotes leukemia in mice Blood 119 2012 4486 4498
22. S. Lin, and R.I. Gregory MicroRNA biogenesis pathways in cancer Nat. Rev. Cancer 15 2015 321 333
23. C.R. Mandel, S. Kaneko, H. Zhang, D. Gebauer, V. Vethantham, J.L. Manley, and L. Tong Polyadenylation factor CPSF-73 is the pre-mRNA 3′-end-processing endonuclease Nature 444 2006 953 956
24. A.K. Marrone, D.B. Stolz, S.I. Bastacky, D. Kostka, A.J. Bodnar, and J. Ho MicroRNA-17∼92 is required for nephrogenesis and renal function J. Am. Soc. Nephrol. 25 2014 1440 1452
25. K.J. Mavrakis, A.L. Wolfe, E. Oricchio, T. Palomero, K. de Keersmaecker, K. McJunkin, J. Zuber, T. James, A.A. Khan, C.S. Leslie, and et al. Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia Nat. Cell Biol. 12 2010 372 379
26. J.T. Mendell miRiad roles for the miR-17-92 cluster in development and disease Cell 133 2008 217 222
27. J.T. Mendell, and E.N. Olson MicroRNAs in stress signaling and human disease Cell 148 2012 1172 1187
28. M. Mori, R. Triboulet, M. Mohseni, K. Schlegelmilch, K. Shrestha, F.D. Camargo, and R.I. Gregory Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer Cell 156 2014 893 906
29. M. Morlando, M. Ballarino, N. Gromak, F. Pagano, I. Bozzoni, and N.J. Proudfoot Primary microRNA transcripts are processed co-transcriptionally Nat. Struct. Mol. Biol. 15 2008 902 909
30. P. Mu, Y.C. Han, D. Betel, E. Yao, M. Squatrito, P. Ogrodowski, E. de Stanchina, A. D'Andrea, C. Sander, and A. Ventura Genetic dissection of the miR-17∼92 cluster of microRNAs in Myc-induced B-cell lymphomas Genes Dev. 23 2009 2806 2811
31. D. Nittner, I. Lambertz, F. Clermont, P. Mestdagh, C. Köhler, S.J. Nielsen, A. Jochemsen, F. Speleman, J. Vandesompele, M.A. Dyer, and et al. Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation Nat. Cell Biol. 14 2012 958 965
32. K.A. O'Donnell, E.A. Wentzel, K.I. Zeller, C.V. Dang, and J.T. Mendell c-Myc-regulated microRNAs modulate E2F1 expression Nature 435 2005 839 843
33. V. Olive, M.J. Bennett, J.C. Walker, C. Ma, I. Jiang, C. Cordon-Cardo, Q.J. Li, S.W. Lowe, G.J. Hannon, and L. He miR-19 is a key oncogenic component of mir-17-92 Genes Dev. 23 2009 2839 2849
34. V. Olive, E. Sabio, M.J. Bennett, C.S. De Jong, A. Biton, J.C. McGann, S.K. Greaney, N.M. Sodir, A.Y. Zhou, A. Balakrishnan, and et al. A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis eLife 2 2013 e00822
35. V. Patel, D. Williams, S. Hajarnis, R. Hunter, M. Pontoglio, S. Somlo, and P. Igarashi miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease Proc. Natl. Acad. Sci. USA 110 2013 10765 10770
36. J.M. Pawlicki, and J.A. Steitz Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function Trends Cell Biol. 20 2010 52 61
37. S.K. Sandhu, M. Fassan, S. Volinia, F. Lovat, V. Balatti, Y. Pekarsky, and C.M. Croce B-cell malignancies in microRNA Eμ-miR-17∼92 transgenic mice Proc. Natl. Acad. Sci. USA 110 2013 18208 18213
38. H. Siomi, and M.C. Siomi Posttranscriptional regulation of microRNA biogenesis in animals Mol. Cell 38 2010 323 332
39. G. Tang, L. Peng, P.R. Baldwin, D.S. Mann, W. Jiang, I. Rees, and S.J. Ludtke EMAN2: an extensible image processing suite for electron microscopy J. Struct. Biol. 157 2007 38 46
40. J.E. Thornton, and R.I. Gregory How does Lin28 let-7 control development and disease? Trends Cell Biol. 22 2012 474 482
41. J.E. Thornton, P. Du, L. Jing, L. Sjekloca, S. Lin, E. Grossi, P. Sliz, L.I. Zon, and R.I. Gregory Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4) Nucleic Acids Res. 42 2014 11777 11791
42. A. Ventura, A.G. Young, M.M. Winslow, L. Lintault, A. Meissner, S.J. Erkeland, J. Newman, R.T. Bronson, D. Crowley, J.R. Stone, and et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters Cell 132 2008 875 886
43. T. Villa, and C. Guthrie The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing Genes Dev. 19 2005 1894 1904
44. S.R. Viswanathan, G.Q. Daley, and R.I. Gregory Selective blockade of microRNA processing by Lin28 Science 320 2008 97 100
45. K.M. Wassarman, and J.A. Steitz Association with terminal exons in pre-mRNAs: a new role for the U1 snRNP? Genes Dev. 7 1993 647 659