-
1
-
-
84939168302
-
-
Online Mendelian Inheritance in Man.
-
Online Mendelian Inheritance in Man. http://www.omim.org .
-
-
-
-
2
-
-
44949211505
-
Managing incidental findings in human subjects research: analysis and recommendations
-
Wolf SM, Lawrenz FP, Nelson CA, Kahn JP, Cho MK, Clayton EW, et al. Managing incidental findings in human subjects research: analysis and recommendations. J Law Med Ethics. 2008;36:219-48. doi: 10.1111/j.1748-720X.2008.00266.x .
-
(2008)
J Law Med Ethics
, vol.36
, pp. 219-248
-
-
Wolf, S.M.1
Lawrenz, F.P.2
Nelson, C.A.3
Kahn, J.P.4
Cho, M.K.5
Clayton, E.W.6
-
3
-
-
84874109945
-
To tell or not to tell? A systematic review of ethical reflections on incidental findings arising in genetics contexts
-
Christenhusz GM, Devriendt K, Dierickx K. To tell or not to tell? A systematic review of ethical reflections on incidental findings arising in genetics contexts. Eur J Hum Genet. 2013;21:248-55. doi: 10.1038/ejhg.2012.130 .
-
(2013)
Eur J Hum Genet
, vol.21
, pp. 248-255
-
-
Christenhusz, G.M.1
Devriendt, K.2
Dierickx, K.3
-
4
-
-
84859561982
-
International normative perspectives on the return of individual research results and incidental findings in genomic biobanks
-
Zawati MH, Knoppers BM. International normative perspectives on the return of individual research results and incidental findings in genomic biobanks. Genet Med. 2012;14:484-9.
-
(2012)
Genet Med
, vol.14
, pp. 484-489
-
-
Zawati, M.H.1
Knoppers, B.M.2
-
5
-
-
84939129245
-
EURAT - Ethical and Legal Aspects of Whole Genome Sequencing.
-
EURAT - Ethical and Legal Aspects of Whole Genome Sequencing. http://www.uni-heidelberg.de/totalsequenzierung/english.html .
-
-
-
-
6
-
-
84939148121
-
Cornerstones for an ethically and legally informed practice of Whole Genome Sequencing.
-
Heidelberg: Marsilius-Kolleg der Universität Heidelberg
-
EURAT-Group. Cornerstones for an ethically and legally informed practice of Whole Genome Sequencing. Heidelberg: Marsilius-Kolleg der Universität Heidelberg; 2013.
-
(2013)
-
-
-
7
-
-
81255159136
-
Extending the scope of diagnostic chromosome analysis: detection of single gene defects using high-resolution SNP microarrays
-
Bruno DL, Stark Z, Amor DJ, Burgess T, Butler K, Corrie S, et al. Extending the scope of diagnostic chromosome analysis: detection of single gene defects using high-resolution SNP microarrays. Hum Mutat. 2011;32:1500-6. doi: 10.1002/humu.21581 .
-
(2011)
Hum Mutat
, vol.32
, pp. 1500-1506
-
-
Bruno, D.L.1
Stark, Z.2
Amor, D.J.3
Burgess, T.4
Butler, K.5
Corrie, S.6
-
8
-
-
84874262681
-
Direct duplication of the Y chromosome with normal phenotype - incidental finding in two cases
-
Kuan LC, Su MT, Kuo PL, Kuo TC. Direct duplication of the Y chromosome with normal phenotype - incidental finding in two cases. Andrologia. 2013;45:140-4. doi: 10.1016/j.pec.2012.09.01010.1111/j.1439-0272.2012.01320.x .
-
(2013)
Andrologia
, vol.45
, pp. 140-144
-
-
Kuan, L.C.1
Su, M.T.2
Kuo, P.L.3
Kuo, T.C.4
-
9
-
-
84898821625
-
An incidental finding of a large genomic deletion of BRCA1 on a molecular karyotype for a 5 year old child
-
Lewis A, James P. An incidental finding of a large genomic deletion of BRCA1 on a molecular karyotype for a 5 year old child. Hered Cancer Clin Pract. 2012;10:A73. doi: 10.1186/1897-4287-10-S2-A73 .
-
(2012)
Hered Cancer Clin Pract
, vol.10
, pp. A73
-
-
Lewis, A.1
James, P.2
-
10
-
-
84874017568
-
Modification of risk for cancer as a coincidental finding in DNA array investigation
-
Rostasy K, Fauth C, Gautsch K, Laimer I, Krabichler B, Wimmer K, et al. Modification of risk for cancer as a coincidental finding in DNA array investigation. Clin Genet. 2013;83:284-7. doi: 10.1111/j.1399-0004.2012.01881.x .
-
(2013)
Clin Genet
, vol.83
, pp. 284-287
-
-
Rostasy, K.1
Fauth, C.2
Gautsch, K.3
Laimer, I.4
Krabichler, B.5
Wimmer, K.6
-
11
-
-
84868686559
-
Diagnostic exome sequencing in persons with severe intellectual disability
-
de Ligt J, Willemsen MH, van Bon BWM, Kleefstra T, Yntema HG, Kroes T, et al. Diagnostic exome sequencing in persons with severe intellectual disability. N Engl J Med. 2012;367:1921-9. doi: 10.1056/NEJMoa1206524 .
-
(2012)
N Engl J Med
, vol.367
, pp. 1921-1929
-
-
Ligt, J.1
Willemsen, M.H.2
Bon, B.W.M.3
Kleefstra, T.4
Yntema, H.G.5
Kroes, T.6
-
12
-
-
84862996297
-
Researcher and institutional review board chair perspectives on incidental findings in genomic research
-
Williams JK, Daack-Hirsch S, Driessnack M, Downing N, Shinkunas L, Brandt D, et al. Researcher and institutional review board chair perspectives on incidental findings in genomic research. Genet Test Mol Biomarkers. 2012;16:508-13. doi: 10.1089/gtmb.2011.0248 .
-
(2012)
Genet Test Mol Biomarkers
, vol.16
, pp. 508-513
-
-
Williams, J.K.1
Daack-Hirsch, S.2
Driessnack, M.3
Downing, N.4
Shinkunas, L.5
Brandt, D.6
-
13
-
-
84870837938
-
Genetics specialists' perspectives on disclosure of genomic incidental findings in the clinical setting
-
Downing NR, Williams JK, Daack-Hirsch S, Driessnack M, Simon CM. Genetics specialists' perspectives on disclosure of genomic incidental findings in the clinical setting. Patient Educ Couns. 2013;90:133-8. doi: 10.1038/gim.2013.7310.1016/j.pec.2012.09.010 .
-
(2013)
Patient Educ Couns
, vol.90
, pp. 133-138
-
-
Downing, N.R.1
Williams, J.K.2
Daack-Hirsch, S.3
Driessnack, M.4
Simon, C.M.5
-
14
-
-
84887447556
-
Researchers' views on return of incidental genomic research results: qualitative and quantitative findings
-
Klitzman R, Appelbaum PS, Fyer A, Martinez J, Buquez B, Wynn J, et al. Researchers' views on return of incidental genomic research results: qualitative and quantitative findings. Genet Med. 2013;15:888-95. doi: 10.1038/gim.2013.14010.1038/gim.2013.87 .
-
(2013)
Genet Med
, vol.15
, pp. 888-895
-
-
Klitzman, R.1
Appelbaum, P.S.2
Fyer, A.3
Martinez, J.4
Buquez, B.5
Wynn, J.6
-
15
-
-
84898441369
-
Processes and factors involved in decisions regarding return of incidental genomic findings in research
-
Klitzman R, Buquez B, Appelbaum PS, Fyer A, Chung WK. Processes and factors involved in decisions regarding return of incidental genomic findings in research. Genet Med. 2014;16:311-7. doi: 10.1038/gim.2014.2910.1038/gim.2013.140 .
-
(2014)
Genet Med
, vol.16
, pp. 311-317
-
-
Klitzman, R.1
Buquez, B.2
Appelbaum, P.S.3
Fyer, A.4
Chung, W.K.5
-
16
-
-
84880535720
-
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing
-
Green RC, Berg JS, Grody WW, Kalia SS, Korf BR, Martin CL, et al. ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genet Med. 2013;15:565-74. doi: 10.1038/gim.2013.8710.1038/gim.2013.73 .
-
(2013)
Genet Med
, vol.15
, pp. 565-574
-
-
Green, R.C.1
Berg, J.S.2
Grody, W.W.3
Kalia, S.S.4
Korf, B.R.5
Martin, C.L.6
-
17
-
-
84939157303
-
Assessment of incidental findings in 232 whole-exome sequences from the Baylor-Hopkins Center for Mendelian Genomics
-
Jurgens J, Ling H, Hetrick K, Pugh E, Schiettecatte F, Doheny K. Assessment of incidental findings in 232 whole-exome sequences from the Baylor-Hopkins Center for Mendelian Genomics. Genet Med. 2015. doi: 10.1038/gim.2014.196 .
-
(2015)
Genet Med
-
-
Jurgens, J.1
Ling, H.2
Hetrick, K.3
Pugh, E.4
Schiettecatte, F.5
Doheny, K.6
-
18
-
-
84991491933
-
The implications of familial incidental findings from exome sequencing: the NIH Undiagnosed Diseases Program experience
-
Lawrence L, Sincan M, Markello T, Adams DR, Gill F, Godfrey R, et al. The implications of familial incidental findings from exome sequencing: the NIH Undiagnosed Diseases Program experience. Genet Med. 2014;16:741-50. doi: 10.1038/gim.2014.29 .
-
(2014)
Genet Med
, vol.16
, pp. 741-750
-
-
Lawrence, L.1
Sincan, M.2
Markello, T.3
Adams, D.R.4
Gill, F.5
Godfrey, R.6
-
19
-
-
84923872701
-
Actionable exomic incidental findings in 6503 participants: challenges of variant classification
-
Amendola LM, Dorschner MO, Robertson PD, Salama JS, Hart R, Shirts BH, et al. Actionable exomic incidental findings in 6503 participants: challenges of variant classification. Genome Res. 2015;25:305-15. doi: 10.1101/gr.183483.114 .
-
(2015)
Genome Res
, vol.25
, pp. 305-315
-
-
Amendola, L.M.1
Dorschner, M.O.2
Robertson, P.D.3
Salama, J.S.4
Hart, R.5
Shirts, B.H.6
-
20
-
-
27144525855
-
Whole-body CT screening: spectrum of findings and recommendations in 1192 patients
-
Furtado CD, Aguirre DA, Sirlin CB, Dang D, Stamato SK, Lee P, et al. Whole-body CT screening: spectrum of findings and recommendations in 1192 patients. Radiology. 2005;237:385-94. doi: 10.1148/radiol.2372041741 .
-
(2005)
Radiology
, vol.237
, pp. 385-394
-
-
Furtado, C.D.1
Aguirre, D.A.2
Sirlin, C.B.3
Dang, D.4
Stamato, S.K.5
Lee, P.6
-
21
-
-
84885785987
-
Clinical whole-exome sequencing for the diagnosis of Mendelian disorders
-
Yang Y, Muzny DM, Reid JG, Bainbridge MN, Willis A, Ward PA, et al. Clinical whole-exome sequencing for the diagnosis of Mendelian disorders. N Engl J Med. 2013;369:1502-11. doi: 10.1056/NEJMoa1306555 .
-
(2013)
N Engl J Med
, vol.369
, pp. 1502-1511
-
-
Yang, Y.1
Muzny, D.M.2
Reid, J.G.3
Bainbridge, M.N.4
Willis, A.5
Ward, P.A.6
-
22
-
-
0004170198
-
The social control of technology.
-
London: Pinter;
-
Collingridge D. The social control of technology. London: Pinter; 1980.
-
(1980)
-
-
Collingridge, D.1
-
23
-
-
77952319734
-
Collingridge's dilemma and technoscience
-
Liebert W, Schmidt J. Collingridge's dilemma and technoscience. Poiesis Prax. 2010;7:55-71. doi: 10.1007/s10202-010-0078-2 .
-
(2010)
Poiesis Prax
, vol.7
, pp. 55-71
-
-
Liebert, W.1
Schmidt, J.2
-
25
-
-
84939197190
-
-
EuroGentest Guidelines for Diagnostic Next Generation Sequencing.
-
EuroGentest Guidelines for Diagnostic Next Generation Sequencing. http://www.eurogentest.org/fileadmin/templates/eugt/pdf/NGS_Guidelines/EuroGentest_NGS_guidelines_2014_-_final_draft_02-12-2014_v2.pdf .
-
-
-
-
26
-
-
44949089705
-
Incidental findings in human subjects research: what do investigators owe research participants?
-
271-211
-
Miller FG, Mello MM, Joffe S. Incidental findings in human subjects research: what do investigators owe research participants? J Law Med Ethics. 2008;36:271-11. doi: 10.1111/j.1748-720X.2008.00269.x .
-
(2008)
J Law Med Ethics
, vol.36
-
-
Miller, F.G.1
Mello, M.M.2
Joffe, S.3
-
27
-
-
84873884799
-
Do researchers have an obligation to actively look for genetic incidental findings?
-
Gliwa C, Berkman BE. Do researchers have an obligation to actively look for genetic incidental findings? Am J Bioethics. 2013;13:32-42. doi: 10.1080/15265161.2012.754062 .
-
(2013)
Am J Bioethics
, vol.13
, pp. 32-42
-
-
Gliwa, C.1
Berkman, B.E.2
-
28
-
-
84930526399
-
ClinGen - The Clinical Genome Resource
-
Rehm HL, Berg JS, Brooks LD, Bustamante CD, Evans JP, Landrum MJ, et al. ClinGen - The Clinical Genome Resource. N Engl J Med. 2015;372:2235-42. doi: 10.1056/NEJMsr1406261 .
-
(2015)
N Engl J Med
, vol.372
, pp. 2235-2242
-
-
Rehm, H.L.1
Berg, J.S.2
Brooks, L.D.3
Bustamante, C.D.4
Evans, J.P.5
Landrum, M.J.6
-
29
-
-
84870900036
-
Deleterious- and disease-allele prevalence in healthy individuals: insights from current predictions, mutation databases, and population-scale resequencing
-
Xue Y, Chen Y, Ayub Q, Huang N, Ball Edward V, Mort M, et al. Deleterious- and disease-allele prevalence in healthy individuals: insights from current predictions, mutation databases, and population-scale resequencing. Am J Hum Genet. 2012;91:1022-32. doi: 10.1016/j.ajhg.2012.10.015 .
-
(2012)
Am J Hum Genet
, vol.91
, pp. 1022-1032
-
-
Xue, Y.1
Chen, Y.2
Ayub, Q.3
Huang, N.4
Ball Edward, V.5
Mort, M.6
-
30
-
-
84861715051
-
Next steps in the sequence: the implications of whole genome sequencing for health in the UK.
-
Cambridge: PHG Foundation;
-
Wright C, Burton H, Hall A, Moorthie S, Pokorska-Bocci A, Sagoo G, et al. Next steps in the sequence: the implications of whole genome sequencing for health in the UK. Cambridge: PHG Foundation; 2011.
-
(2011)
-
-
Wright, C.1
Burton, H.2
Hall, A.3
Moorthie, S.4
Pokorska-Bocci, A.5
Sagoo, G.6
-
31
-
-
84887439425
-
Recommendations for returning genomic incidental findings? We need to talk!
-
Burke W, Matheny Antommaria AH, Bennett R, Botkin J, Clayton EW, Henderson GE, et al. Recommendations for returning genomic incidental findings? We need to talk! Genet Med. 2013;15:854-9. doi: 10.1038/gim.2013.113 .
-
(2013)
Genet Med
, vol.15
, pp. 854-859
-
-
Burke, W.1
Matheny Antommaria, A.H.2
Bennett, R.3
Botkin, J.4
Clayton, E.W.5
Henderson, G.E.6
-
32
-
-
84859566974
-
Managing incidental findings and research results in genomic research involving biobanks & archived datasets
-
Wolf SM, Crock BN, Van Ness B, Lawrenz F, Kahn JP, Beskow LM, et al. Managing incidental findings and research results in genomic research involving biobanks & archived datasets. Genet Med. 2012;14:361-84. doi: 10.1038/gim.2012.23 .
-
(2012)
Genet Med
, vol.14
, pp. 361-384
-
-
Wolf, S.M.1
Crock, B.N.2
Ness, B.3
Lawrenz, F.4
Kahn, J.P.5
Beskow, L.M.6
-
33
-
-
79959276553
-
Deploying whole genome sequencing in clinical practice and public health: meeting the challenge one bin at a time
-
Berg JSKM, Evans JP. Deploying whole genome sequencing in clinical practice and public health: meeting the challenge one bin at a time. Genet Med. 2011;13:499-504. doi: 10.1097/GIM.0b013e318220aaba .
-
(2011)
Genet Med
, vol.13
, pp. 499-504
-
-
Berg, J.S.K.M.1
Evans, J.P.2
-
34
-
-
84924992117
-
Defining and managing incidental findings in genetic and genomic practice
-
Shkedi-Rafid S, Dheensa S, Crawford G, Fenwick A, Lucassen A. Defining and managing incidental findings in genetic and genomic practice. J Med Genet. 2014;51:715-23. doi: 10.1136/jmedgenet-2014-102435 .
-
(2014)
J Med Genet
, vol.51
, pp. 715-723
-
-
Shkedi-Rafid, S.1
Dheensa, S.2
Crawford, G.3
Fenwick, A.4
Lucassen, A.5
|