Epidemiological, clinical, outcome and antibiotic susceptibility differences between PVL positive and PVL negative Staphylococcus aureus infections in Western Australia: A case control study

BMC Infectious Diseases

Volumn 15, Issue 1, 2015, Pages

  Boan, Peter ^a   Tan, Hui Leen ^a,b   Pearson, Julie ^a,b   Coombs, Geoffrey ^a,b   Heath, Christopher H ^a   Robinson, James Owen ^a,b  

^a ROYAL PERTH HOSPITAL   (Australia)

^b PATHWEST LABORATORY MEDICINE   (Australia)

Author keywords

MRSA; Panton Valentine Leucocidin; PVL; Staphylococcus aureus

Indexed keywords

CLINDAMYCIN; ERYTHROMYCIN; LINCOSAMIDE; LINEZOLID; LYSOSTAPHIN; METICILLIN; PANTON VALENTINE LEUKOCIDIN; PSEUDOMONIC ACID; BACTERIAL TOXIN; EXOTOXIN; LEUKOCIDIN; PANTON-VALENTINE LEUKOCIDIN;

ADULT; AGE; ANTIBIOTIC SENSITIVITY; ARTICLE; AUSTRALIA; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CASE CONTROL STUDY; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN TISSUE; INDIGENOUS PEOPLE; INTRAVENOUS DRUG ABUSE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MORTALITY; NONHUMAN; PVL GENE; SEX DIFFERENCE; SKIN INFECTION; SOFT TISSUE INFECTION; STAPHYLOCOCCUS INFECTION; COMMUNITY-ACQUIRED INFECTIONS; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; RESPIRATORY TRACT INFECTIONS; RISK FACTOR; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL INFECTIONS;

ADULT; BACTERIAL TOXINS; CASE-CONTROL STUDIES; CLINDAMYCIN; COMMUNITY-ACQUIRED INFECTIONS; EXOTOXINS; FEMALE; HUMANS; LEUKOCIDINS; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; RESPIRATORY TRACT INFECTIONS; RISK FACTORS; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL INFECTIONS; WESTERN AUSTRALIA;

EID: 84939129139     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-014-0742-6     Document Type: Article

References (27)

1. Udo EE, Pearman JW, Grubb WB. Genetic analysis of community isolates of methicillin-resistant Staphylococcus aureus in Western Australia. J Hosp Infect. 1993;25:97-108.
2. Moran GJ, Krishnadasan A, Gorwitz RJ, Fosheim GE, McDougal LK, Carey RB, et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med. 2006;355:666-74.
3. Vandenesch F, Naimi T, Enright MC, Lina G, Nimmo GR, Heffernan H, et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis. 2003;9:978-84.
4. Wehrhahn MC, Robinson JO, Pearson JC, O'Brien FG, Tan HL, Coombs GW, et al. Clinical and laboratory features of invasive community-onset methicillin-resistant Staphylococcus aureus infection: a prospective case-control study. Eur J Clin Microbiol Infect Dis. 2010;29:1025-33.
5. Miller LG, Perdreau-Remington F, Rieg G, Mehdi S, Perlroth J, Bayer AS, et al. Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med. 2005;352:1445-53.
6. Gillet Y, Issartel B, Vanhems P, Fournet JC, Lina G, Bes M, et al. Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet. 2002;359:753-9.
7. Boyle-Vavra S, Ereshefsky B, Wang CC, Daum RS. Successful multiresistant community-associated methicillin-resistant Staphylococcus aureus lineage from Taipei, Taiwan, that carries either the novel Staphylococcal chromosome cassette mec (SCCmec) type VT or SCCmec type IV. J Clin Microbiol. 2005;43:4719-30.
8. Robinson JO, Pearson JC, Christiansen KJ, Coombs GW, Murray RJ. Community-associated versus healthcare-associated methicillin-resistant Staphylococcus aureus bacteraemia: a 10-year retrospective review. Eur J Clin Microbiol Infect Dis. 2009;28:353-61.
9. National Health and Medical Research Council, Commonwealth of Australia: When does quality assurance in health care require independent ethical review? Advice to institutions, human research ethics committees and health care professionals 2003. [http://www.nhmrc.gov.au/guidelines/publications/e46]
10. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial testing: 18th informational supplement. CLSI document M100-S18. Wayne, PA: Clinical and Laboratory Standards Institute; 2008.
11. Costa AM, Kay I, Palladino S. Rapid detection of mecA and nuc genes in Staphylococci by real-time multiplex polymerase chain reaction. Diagn Microbiol and Infect Dis. 2005;51:13-7.
12. O'Brien FG, Pearman JW, Gracey M, Riley TV, Grubb WB. Community strain of methicillin-resistant Staphylococcus aureus involved in a hospital outbreak. J Clin Microbiol. 1999;37:2858-62.
13. Fey PD, Said-Salim B, Rupp ME, Hinrichs SH, Boxrud DJ, Davis CC, et al. Comparative molecular analysis of community- or hospital-acquired methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2003;47:196-203.
14. Masiuk H, Kopron K, Grumann D, Goerke C, Kolata J, Jursa-Kulesza J, et al. Association of recurrent furunculosis with Panton-Valentine leukocidin and the genetic background of Staphylococcus aureus. J Clin Microbiol. 2010;48:1527-35.
15. Neela V, Ehsanollah GR, Zamberi S, Van Belkum A, Mariana NS. Prevalence of Panton-Valentine leukocidin genes among carriage and invasive Staphylococcus aureus isolates in Malaysia. Int J Infect Dis. 2009;13:e131-132.
16. Munckhof WJ, Nimmo GR, Schooneveldt JM, Schlebusch S, Stephens AJ, Williams G, et al. Nasal carriage of Staphylococcus aureus, including community-associated methicillin-resistant strains, in Queensland adults. Clin Microbiol Infect. 2009;15:149-55.
17. Muttaiyah S, Coombs G, Pandey S, Reed P, Ritchie S, Lennon D, et al. Incidence, risk factors, and outcomes of Panton-Valentine leukocidin-positive methicillin-susceptible Staphylococcus aureus infections in Auckland, New Zealand. J Clin Microbiol. 2010;48:3470-4.
18. Tong SY, Lilliebridge RA, Bishop EJ, Cheng AC, Holt DC, McDonald MI, et al. Clinical correlates of Panton-Valentine leukocidin (PVL), PVL isoforms, and clonal complex in the Staphylococcus aureus population of Northern Australia. J Infect Dis. 2010;202:760-9.
19. Robinson DA, Kearns AM, Holmes A, Morrison D, Grundmann H, Edwards G, et al. Re-emergence of early pandemic Staphylococcus aureus as a community-acquired meticillin-resistant clone. Lancet. 2005;365:1256-8.
20. Donahue JA, Baldwin JN. Hemolysin and leukocidin production by 80/81 strains of Staphylococcus aureus. J Infect Dis. 1996;116:324-8.
21. Gauduchon V, Cozon G, Vandenesch F, Genestier AL, Eyssade N, Peyrol S, et al. Neutralization of Staphylococcus aureus Panton Valentine leukocidin by intravenous immunoglobulin in vitro. J Infect Dis. 2004;189:346-53.
22. Nimmo GR, Schooneveldt JM, Sutherland JL, Power S, Olesen D, Selvey C, et al. Epidemiology of non-multiresistant methicillin-resistant Staphylococcus aureus infection in Queensland, Australia: associations with indigenous populations and Panton-Valentine leukocidin. Eur J Clin Microbiol Infect Dis. 2010;29:1253-9.
23. Lina G, Piemont Y, Godail-Gamot F, Bes M, Peter MO, Gauduchon V, et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis. 1999;29:1128-32.
24. Shallcross LJ, Fragaszy E, Johnson AM, Hayward AC. The role of Panton-Valentine leucocidin toxin in Staphylococcal disease: a systematic review and meta-analysis. Lancet Infect Dis. 2013;13:43-54.
25. Al-Rawahi GN, Reynolds S, Porter SD, Forrester L, Kishi L, Chong T, et al. Community-associated CMRSA-10 (USA-300) is the predominant strain among methicillin-resistant Staphylococcus aureus strains causing skin and soft tissue infections in patients presenting to the emergency department of a Canadian tertiary care hospital. J Emerg Med. 2010;38:6-11.
26. Murray RJ, Robinson JO, White JN, Hughes F, Coombs GW, Pearson JC, et al. Community-acquired pneumonia due to pandemic A (H1N1) 2009 influenza virus and methicillin resistant Staphylococcus aureus co-infection. PloS One. 2010;5:e8705.
27. Gillet Y, Dumitrescu O, Tristan A, Dauwalder O, Javouhey E, Floret D, et al. Pragmatic management of Panton-Valentine leukocidin-associated staphylococcal diseases. Int J Antimicrob Agents. 2010;38:457-64.