Clinical and laboratory features of invasive community-onset methicillin-resistant Staphylococcus aureus infection: A prospective case-control study

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 29, Issue 8, 2010, Pages 1025-1033

  Wehrhahn, M C ^a,e   Robinson, J O ^a,b   Pearson, J C ^b   O'Brien, F G ^b   Tan, H L ^b   Coombs, G W ^a,b   Pascoe, E M ^c   Lee, R ^a   Salvaris, P ^d   Salvaris, R ^d   New, D ^d   Murray, R J ^a,d  

^a ROYAL PERTH HOSPITAL   (Australia)

^b CURTIN UNIVERSITY   (Australia)

^c PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e LIVERPOOL HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CIPROFLOXACIN; CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; OXACILLIN; PANTON VALENTINE LEUKOCIDIN; PENICILLIN G; RIFAMPICIN; TETRACYCLINE; VANCOMYCIN; BACTERIAL TOXIN; EXOTOXIN; LEUKOCIDIN; PANTON-VALENTINE LEUKOCIDIN; VIRULENCE FACTOR;

ABORIGINE; ADOLESCENT; ADULT; AGE; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; CASE CONTROL STUDY; CHILD; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE SEVERITY; ENDOCARDITIS; FEMALE; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MORBIDITY; MORTALITY; NONHUMAN; NURSING HOME PATIENT; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHOOL CHILD; SKIN INFECTION; STAPHYLOCOCCUS AUREUS; CLASSIFICATION; COMMUNITY ACQUIRED INFECTION; ETHNIC GROUP; GENETICS; ISOLATION AND PURIFICATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; RISK FACTOR; STAPHYLOCOCCUS INFECTION; STATISTICS AND NUMERICAL DATA; TEACHING HOSPITAL; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BACTERIAL TOXINS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; ETHNIC GROUPS; EXOTOXINS; FEMALE; HOSPITALIZATION; HOSPITALS, TEACHING; HUMANS; LEUKOCIDINS; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; STAPHYLOCOCCAL INFECTIONS; VIRULENCE FACTORS; YOUNG ADULT;

EID: 77955471493     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-010-0973-4     Document Type: Article

References (41)

1. GR Nimmo GW Coombs 2008 Community-associated methicillin-resistant Staphylococcus aureus (MRSA) in Australia Int J Antimicrob Agents 31 401 410 10.1016/j.ijantimicag.2007.08.011 1:CAS:528:DC%2BD1cXkvVOksbY%3D 18342492
2. JA Otter GL French 2008 The emergence of community-associated methicillin-resistant Staphylococcus aureus at a London teaching hospital, 2000-2006 Clin Microbiol Infect 14 670 676 10.1111/j.1469-0691.2008.02017.x 1:STN:280:DC%2BD1czpt1ensQ%3D%3D 18558939 (Pubitemid 351837027)
3. GJ Moran A Krishnadasan RJ Gorwitz, et al. 2006 Methicillin-resistant S. aureus infections among patients in the emergency department N Engl J Med 355 666 674 10.1056/NEJMoa055356 1:CAS:528:DC%2BD28Xot12mtLo%3D 16914702
4. BE Gonzalez KG Hulten MK Dishop, et al. 2005 Pulmonary manifestations in children with invasive community-acquired Staphylococcus aureus infection Clin Infect Dis 41 583 590 10.1086/432475 16080077 (Pubitemid 41170343)
5. GR Nimmo GW Coombs JC Pearson, et al. 2006 Methicillin-resistant Staphylococcus aureus in the Australian community: an evolving epidemic Med J Aust 184 384 388 16618236
6. Y Gillet B Issartel P Vanhems, et al. 2002 Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients Lancet 359 753 759 10.1016/S0140-6736(02)07877-7 1:CAS:528:DC%2BD38XhvVWhtrw%3D 11888586 (Pubitemid 34215075)
7. LG Miller F Perdreau-Remington G Rieg, et al. 2005 Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles N Engl J Med 352 1445 1453 10.1056/NEJMoa042683 1:CAS:528: DC%2BD2MXjtVWltro%3D 15814880 (Pubitemid 40471452)
8. RJ Murray TT Lim JC Pearson, et al. 2004 Community-onset methicillin-resistant Staphylococcus aureus bacteremia in Northern Australia Int J Infect Dis 8 275 283 10.1016/j.ijid.2003.11.008 15325596 (Pubitemid 39119851)
9. JO Robinson JC Pearson KJ Christiansen, et al. 2009 Community-associated versus healthcare-associated methicillin-resistant Staphylococcus aureus bacteraemia: a 10-year retrospective review Eur J Clin Microbiol Infect Dis 28 353 361 10.1007/s10096-008-0632-1 1:STN:280:DC%2BD1M3ksF2rtA%3D%3D 18850122
10. BC Millar BD Prendergast JE Moore 2008 Community-associated MRSA (CA-MRSA): an emerging pathogen in infective endocarditis J Antimicrob Chemother 61 1 7 10.1093/jac/dkm410 1:CAS:528:DC%2BD1cXhtFWhtQ%3D%3D 17962214
11. J Etienne 2005 Panton-Valentine leukocidin: a marker of severity for Staphylococcus aureus infection? Clin Infect Dis 41 591 593 10.1086/432481 16080078 (Pubitemid 41170344)
12. E Rubinstein MH Kollef D Nathwani 2008 Pneumonia caused by methicillin-resistant Staphylococcus aureus Clin Infect Dis 46 S378 S385 10.1086/533594 18462093 (Pubitemid 351717325)
13. F Vandenesch T Naimi MC Enright, et al. 2003 Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence Emerg Infect Dis 9 978 984 12967497
14. RM Klevens MA Morrison J Nadle, et al. 2007 Invasive methicillin- resistant Staphylococcus aureus infections in the United States JAMA 298 1763 1771 10.1001/jama.298.15.1763 1:CAS:528:DC%2BD2sXht1Sisb7J 17940231 (Pubitemid 47598444)
15. DJ Skiest K Brown TW Cooper, et al. 2007 Prospective comparison of methicillin-susceptible and methicillin-resistant community-associated Staphylococcus aureus infections in hospitalized patients J Infect 54 427 434 10.1016/j.jinf.2006.09.012 17070598 (Pubitemid 46567511)
16. WJ Munckhof GR Nimmo J Carney, et al. 2008 Methicillin-susceptible, non-multiresistant methicillin-resistant and multiresistant methicillin- resistant Staphylococcus aureus infections: a clinical, epidemiological and microbiological comparative study Eur J Clin Microbiol Infect Dis 27 355 364 10.1007/s10096-007-0449-3 1:CAS:528:DC%2BD1cXlt1Cqsb4%3D 18278529
17. F Rozgonyi E Kocsis K Kristóf, et al. 2007 Is MRSA more virulent than MSSA? Clin Microbiol Infect 13 843 845 10.1111/j.1469-0691.2007.01780.x 1:STN:280:DC%2BD2svmvVehug%3D%3D 17686137 (Pubitemid 47244132)
18. Commonwealth of Australia (2004) Infection control guidelines for the prevention of transmission of infectious diseases in the health care setting. Appendix 1, 7-8. Available online at: http://www.health.gov.au/internet/main/ publishing.nsf/Content/icg-guidelines-index.htm. Accessed 6 January 2009
19. Australian Bureau of Statistics (ABS) (2008) Socio-economic indexes for areas (SEIFA)-technical paper. Available online at: http://www.abs.gov.au/ ausstats/abs@nsf/mf/2039.0.55.001/. Accessed 17 December 2008
20. KB Laupland DL Church M Mucenski, et al. 2003 Population-based study of the epidemiology of and the risk factors for invasive Staphylococcus aureus infections J Infect Dis 187 1452 1459 10.1086/374621 12717627 (Pubitemid 36549691)
21. SK Fridkin JC Hageman MHS Morrison, et al. 2005 Methicillin-resistant Staphylococcus aureus disease in three communities N Engl J Med 352 1436 1444 10.1056/NEJMoa043252 1:CAS:528:DC%2BD2MXjtVWltr0%3D 15814879 (Pubitemid 40471451)
22. JR Le Gall S Lemeshow F Saulnier 1993 A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study JAMA 270 2957 2963 10.1001/jama.270.24.2957 8254858 (Pubitemid 24000804)
23. JS Li DJ Sexton N Mick, et al. 2000 Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis Clin Infect Dis 30 633 638 10.1086/313753 1:STN:280:DC%2BD3czotl2isA%3D%3D 10770721
24. MS Morgan 2007 Diagnosis and treatment of Panton-Valentine leukocidin (PVL)-associated staphylococcal pneumonia Int J Antimicrob Agents 30 289 296 10.1016/j.ijantimicag.2007.04.019 1:CAS:528:DC%2BD2sXhtVWiurbM 17629464 (Pubitemid 47361709)
25. Clinical and Laboratory Standards Institute (CLSI) (2006) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard. Seventh edition. CLSI Document M7-A7. CLSI, Wayne, PA, USA
26. Report of the Comité de l'Antibiogramme de la Societé Française de Microbiologie (1996) Clin Microbiol Infect 2:S48
27. KR Fiebelkorn SA Crawford ML McElmeel, et al. 2003 Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus and coagulase-negative staphylococci J Clin Microbiol 41 4740 4744 10.1128/JCM.41.10.4740-4744.2003 1:CAS:528:DC%2BD3sXovFKjt70%3D 14532213 (Pubitemid 37259787)
28. AM Costa I Kay S Palladino 2005 Rapid detection of mecA and nuc genes in staphylococci by real-time multiplex polymerase chain reaction Diagn Microbiol Infect Dis 51 13 17 10.1016/j.diagmicrobio.2004.08.014 1:CAS:528:DC%2BD2MXkt12q 15629224 (Pubitemid 40040563)
29. FG O'Brien EE Udo WB Grubb 2006 Contour-clamped homogeneous electric field electrophoresis of Staphylococcus aureus Nat Protoc 1 3028 3033 10.1038/nprot.2006.382 17406564
30. MC Enright NP Day CE Davies, et al. 2000 Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus J Clin Microbiol 38 1008 1015 1:CAS:528: DC%2BD3cXitVemurg%3D 10698988
31. GW Coombs JC Pearson FG O'Brien, et al. 2006 Methicillin-resistant Staphylococcus aureus clones, Western Australia Emerg Infect Dis 12 241 247 16494749
32. PD Fey B Saïd-Salim ME Rupp, et al. 2003 Comparative molecular analysis of community- or hospital-acquired methicillin-resistant Staphylococcus aureus Antimicrob Agents Chemother 47 196 203 10.1128/AAC.47.1.196-203.2003 1:CAS:528:DC%2BD3sXis12gug%3D%3D 12499191 (Pubitemid 36070364)
33. SYC Tong MI McDonald DC Holt, et al. 2008 Global implications of the emergence of community-associated methicillin-resistant Staphylococcus aureus in indigenous populations Clin Infect Dis 46 1871 1878 10.1086/588301 18462175
34. HC Baggett TW Hennessy K Rudolph, et al. 2004 Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska J Infect Dis 189 1565 1573 10.1086/383247 15116291 (Pubitemid 38648283)
35. SCRGSP (Steering Committee for the Review of Government Service Provision) (2009) Overcoming indigenous disadvantage: key indicators 2009. Productivity Commission, Canberra
36. LG Miller F Perdreau-Remington AS Bayer, et al. 2007 Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus infection from methicillin- susceptible S. aureus infection: a prospective investigation Clin Infect Dis 44 471 482 10.1086/511033 1:CAS:528:DC%2BD2sXisVGksr8%3D 17243048 (Pubitemid 46233247)
37. RJ Gordon FD Lowy 2008 Pathogenesis of methicillin-resistant Staphylococcus aureus infection Clin Infect Dis 46 S350 S359 10.1086/533591 1:CAS:528:DC%2BD1cXnsFKqt74%3D 18462090 (Pubitemid 351717322)
38. AY Peleg WJ Munckhof SL Kleinschmidt, et al. 2005 Life-threatening community-acquired methicillin-resistant Staphylococcus aureus infection in Australia Eur J Clin Microbiol Infect Dis 24 384 387 10.1007/s10096-005-1329-3 1:STN:280:DC%2BD2MzktFOqtQ%3D%3D 15926063 (Pubitemid 40933912)
39. MJ Ellington R Hope M Ganner, et al. 2007 Is Panton-Valentine leucocidin associated with the pathogenesis of Staphylococcus aureus bacteraemia in the UK? J Antimicrob Chemother 60 402 405 10.1093/jac/dkm206 1:CAS:528: DC%2BD2sXos12ms7c%3D 17562682 (Pubitemid 47243893)
40. S Monecke P Slickers MJ Ellington, et al. 2007 High diversity of Panton-Valentine leukocidin-positive, methicillin-susceptible isolates of Staphylococcus aureus and implications for the evolution of community-associated methicillin-resistant S. aureus Clin Microbiol Infect 13 1157 1164 10.1111/j.1469-0691.2007.01833.x 1:STN:280:DC%2BD2snmsF2gsA%3D%3D 17949441 (Pubitemid 350056120)
41. S Chavez-Bueno B Bozdogan K Katz, et al. 2005 Inducible clindamycin resistance and molecular epidemiologic trends of pediatric community-acquired methicillin-resistant Staphylococcus aureus in Dallas, Texas Antimicrob Agents Chemother 49 2283 2288 10.1128/AAC.49.6.2283-2288.2005 1:CAS:528: DC%2BD2MXkvFCgsr4%3D 15917522 (Pubitemid 40734455)