Withaferin a-caused production of intracellular reactive oxygen species modulates apoptosis via PI3K/Akt and JNKinase in rabbit articular chondrocytes

Journal of Korean Medical Science

Volumn 29, Issue 8, 2014, Pages 1042-1053

  Yu, Seon Mi ^a   Kim, Song Ja ^a  

^a Kongju National University   (South Korea)

Author keywords

Apoptosis; Chondrocytes; Reactive oxygen species

Indexed keywords

ANTIINFLAMMATORY AGENT; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; WITHAFERIN A; WITHANOLIDE;

ANIMAL; APOPTOSIS; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; RABBIT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; DOSE-RESPONSE RELATIONSHIP, DRUG; MAP KINASE KINASE 4; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RABBITS; REACTIVE OXYGEN SPECIES; WITHANOLIDES;

EID: 84938991415     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2014.29.8.1042     Document Type: Article

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