-
1
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
Hansen, M. et al. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6, 95-110 (2007).
-
(2007)
Aging Cell
, vol.6
, pp. 95-110
-
-
Hansen, M.1
-
2
-
-
33846418352
-
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
-
Pan, K. Z. et al. Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6, 111-119 (2007).
-
(2007)
Aging Cell
, vol.6
, pp. 111-119
-
-
Pan, K.Z.1
-
3
-
-
33847199335
-
EIF4E function in somatic cells modulates ageing in Caenorhabditis elegans
-
Syntichaki, P., Troulinaki, K. & Tavernarakis, N. eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature 445, 922-926 (2007).
-
(2007)
Nature
, vol.445
, pp. 922-926
-
-
Syntichaki, P.1
Troulinaki, K.2
Tavernarakis, N.3
-
4
-
-
41949089130
-
Yeast life span extension by depletion of 60S ribosomal subunits is mediated by Gcn4
-
Steffen, K. K. et al. Yeast life span extension by depletion of 60S ribosomal subunits is mediated by Gcn4. Cell 133, 292-302 (2008).
-
(2008)
Cell
, vol.133
, pp. 292-302
-
-
Steffen, K.K.1
-
5
-
-
34247569105
-
Lifespan regulation by evolutionarily conserved genes essential for viability
-
Curran, S. P. & Ruvkun, G. Lifespan regulation by evolutionarily conserved genes essential for viability. PLoS Genet. 3, e56 (2007).
-
(2007)
PLoS Genet.
, vol.3
, pp. e56
-
-
Curran, S.P.1
Ruvkun, G.2
-
6
-
-
27744511769
-
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
-
Kaeberlein, M. et al. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310, 1193-1196 (2005).
-
(2005)
Science
, vol.310
, pp. 1193-1196
-
-
Kaeberlein, M.1
-
7
-
-
33847680031
-
Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span
-
Chiocchetti, A. et al. Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span. Exp. Gerontol. 42, 275-286 (2007).
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 275-286
-
-
Chiocchetti, A.1
-
8
-
-
70349669095
-
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
-
Selman, C. et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science 326, 140-144 (2009).
-
(2009)
Science
, vol.326
, pp. 140-144
-
-
Selman, C.1
-
9
-
-
3042648746
-
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
-
Kapahi, P. et al. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 14, 885-890 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 885-890
-
-
Kapahi, P.1
-
10
-
-
78049362580
-
Protein synthesis and the antagonistic pleiotropy hypothesis of aging
-
Kapahi, P. Protein synthesis and the antagonistic pleiotropy hypothesis of aging. Adv. Exp. Med. Biol. 694, 30-37 (2010).
-
(2010)
Adv. Exp. Med. Biol.
, vol.694
, pp. 30-37
-
-
Kapahi, P.1
-
11
-
-
79959981053
-
Life span extension via eIF4G inhibition is mediated by post transcriptional remodeling of stress response gene expression in C. Elegans
-
Rogers, A. N. et al. Life span extension via eIF4G inhibition is mediated by post transcriptional remodeling of stress response gene expression in C. elegans. Cell Metab. 14, 55-66 (2011).
-
(2011)
Cell Metab.
, vol.14
, pp. 55-66
-
-
Rogers, A.N.1
-
12
-
-
70349438679
-
4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila
-
Zid, B. M. et al. 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. Cell 139, 149-160 (2009).
-
(2009)
Cell
, vol.139
, pp. 149-160
-
-
Zid, B.M.1
-
13
-
-
84867919856
-
Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress
-
Gerashchenko, M. V., Lobanov, A. V. & Gladyshev, V. N. Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress. Proc. Natl Acad. Sci. USA 109, 17394-17399 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 17394-17399
-
-
Gerashchenko, M.V.1
Lobanov, A.V.2
Gladyshev, V.N.3
-
14
-
-
77956334156
-
Insulin-like signaling determines survival during stress via post transcriptional mechanisms in C. Elegans
-
McColl, G. et al. Insulin-like signaling determines survival during stress via post transcriptional mechanisms in C. elegans. Cell Metab. 12, 260-272 (2010).
-
(2010)
Cell Metab.
, vol.12
, pp. 260-272
-
-
McColl, G.1
-
15
-
-
33749379882
-
Global translational responses to oxidative stress impact upon multiple levels of protein synthesis
-
Shenton, D. et al. Global translational responses to oxidative stress impact upon multiple levels of protein synthesis. J. Biol. Chem. 281, 29011-29021 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29011-29021
-
-
Shenton, D.1
-
16
-
-
61649096857
-
Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast
-
Lawless, C. et al. Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast. BMC Genomics 10, 7 (2009).
-
(2009)
BMC Genomics
, vol.10
, pp. 7
-
-
Lawless, C.1
-
17
-
-
84864828979
-
Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins
-
Chan, C. T. Y. et al. Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Nat. Commun. 3, 937 (2012).
-
(2012)
Nat. Commun.
, vol.3
, pp. 937
-
-
Chan, C.T.Y.1
-
18
-
-
84861418314
-
Specialized ribosomes: A new frontier in gene regulation and organismal biology
-
Xue, S. & Barna, M. Specialized ribosomes: a new frontier in gene regulation and organismal biology. Nat. Rev. Mol. Cell Biol. 13, 355-369 (2012).
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 355-369
-
-
Xue, S.1
Barna, M.2
-
19
-
-
84876043662
-
Specialization from synthesis: How ribosome diversity can customize protein function
-
Filipovska, A. & Rackham, O. Specialization from synthesis: how ribosome diversity can customize protein function. FEBS Lett. 587, 1189-1197 (2013).
-
(2013)
FEBS Lett.
, vol.587
, pp. 1189-1197
-
-
Filipovska, A.1
Rackham, O.2
-
20
-
-
84879963839
-
Specialized yeast ribosomes: A customized tool for selective mRNA translation
-
Bauer, J. W. et al. Specialized yeast ribosomes: a customized tool for selective mRNA translation. PLoS ONE 8, e67609 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e67609
-
-
Bauer, J.W.1
-
21
-
-
78249285607
-
Identification of evolutionarily conserved genetic regulators of cellular aging
-
Laschober, G. T. et al. Identification of evolutionarily conserved genetic regulators of cellular aging. Aging Cell 9, 1084-1097 (2010).
-
(2010)
Aging Cell
, vol.9
, pp. 1084-1097
-
-
Laschober, G.T.1
-
22
-
-
84863227058
-
ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis
-
Dellago, H. et al. ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis. Aging 4, 290-304 (2012).
-
(2012)
Aging
, vol.4
, pp. 290-304
-
-
Dellago, H.1
-
23
-
-
0035736207
-
Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome
-
Doll, A. & Grzeschik, K. H. Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome. Cytogenet. Cell Genet. 95, 20-27 (2001).
-
(2001)
Cytogenet. Cell Genet.
, vol.95
, pp. 20-27
-
-
Doll, A.1
Grzeschik, K.H.2
-
24
-
-
33751524705
-
Yeast as a model for chronological and reproductive aging-A comparison
-
Laun, P., Rinnerthaler, M., Bogengruber, E., Heeren, G. & Breitenbach, M. Yeast as a model for chronological and reproductive aging-a comparison. Exp. Gerontol. 41, 1208-1212 (2006).
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 1208-1212
-
-
Laun, P.1
Rinnerthaler, M.2
Bogengruber, E.3
Heeren, G.4
Breitenbach, M.5
-
25
-
-
0037280096
-
SOD2 functions downstream of Sch9 to extend longevity in yeast
-
Fabrizio, P. et al. SOD2 functions downstream of Sch9 to extend longevity in yeast. Genetics 163, 35-46 (2003).
-
(2003)
Genetics
, vol.163
, pp. 35-46
-
-
Fabrizio, P.1
-
26
-
-
30944458446
-
Extension of chronological life span in yeast by decreased TOR pathway signaling
-
Powers, R. W. et al. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev. 20, 174-184 (2006).
-
(2006)
Genes Dev.
, vol.20
, pp. 174-184
-
-
Powers, R.W.1
-
27
-
-
0037125961
-
RNA methyltransferases utilize two cysteine residues in the formation of 5-methylcytosine
-
King, M. Y. & Redman, K. L. RNA methyltransferases utilize two cysteine residues in the formation of 5-methylcytosine. Biochemistry 41, 11218-11225 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 11218-11225
-
-
King, M.Y.1
Redman, K.L.2
-
28
-
-
84885993080
-
Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
-
Sharma, S., Yang, J., Watzinger, P., Kötter, P. & Entian, K.-D. Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively. Nucleic Acids Res. 41, 9062-9076 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 9062-9076
-
-
Sharma, S.1
Yang, J.2
Watzinger, P.3
Kötter, P.4
Entian, K.-D.5
-
29
-
-
0142184341
-
Global analysis of protein localization in budding yeast
-
Huh, W.-K. et al. Global analysis of protein localization in budding yeast. Nature 425, 686-691 (2003).
-
(2003)
Nature
, vol.425
, pp. 686-691
-
-
Huh, W.-K.1
-
30
-
-
84868250838
-
The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits
-
Sardana, R. & Johnson, A. W. The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits. Mol. Biol. Cell 23, 4313-4322 (2012).
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 4313-4322
-
-
Sardana, R.1
Johnson, A.W.2
-
31
-
-
42149116826
-
A map of human protein interactions derived from co-expression of human mRNAs and their orthologs
-
Ramani, A. K. et al. A map of human protein interactions derived from co-expression of human mRNAs and their orthologs. Mol. Syst. Biol. 4, 180 (2008).
-
(2008)
Mol. Syst. Biol.
, vol.4
, pp. 180
-
-
Ramani, A.K.1
-
32
-
-
84907198762
-
A cluster of methylations in the domain IV of 25S rRNA is required for ribosome stability
-
Gigova, A., Duggimpudi, S., Pollex, T., Schaefer, M. & Koš, M. A cluster of methylations in the domain IV of 25S rRNA is required for ribosome stability. RNA 20, 1632-1644 (2014).
-
(2014)
RNA
, vol.20
, pp. 1632-1644
-
-
Gigova, A.1
Duggimpudi, S.2
Pollex, T.3
Schaefer, M.4
Koš, M.5
-
33
-
-
0032918555
-
The RNA modification database: 1999 update
-
Rozenski, J., Crain, P. F. & McCloskey, J. A. The RNA modification database: 1999 update. Nucleic Acids Res. 27, 196-197 (1999).
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 196-197
-
-
Rozenski, J.1
Crain, P.F.2
McCloskey, J.A.3
-
34
-
-
85031949575
-
Eukaryotic polyribosome profile analysis
-
Esposito, A. M. et al. Eukaryotic polyribosome profile analysis. JoVE 40 (1948).
-
(1948)
JoVE
, pp. 40
-
-
Esposito, A.M.1
-
35
-
-
84877350071
-
Identification of direct targets and modified bases of RNA cytosine methyltransferases
-
Khoddami, V. & Cairns, B. R. Identification of direct targets and modified bases of RNA cytosine methyltransferases. Nat. Biotechnol. 31, 458-464 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 458-464
-
-
Khoddami, V.1
Cairns, B.R.2
-
36
-
-
0027771804
-
A C. Elegans mutat that lives twice as long as wild-type
-
Kenyon, C. et al. A C. elegans mutat that lives twice as long as wild-type. Nature 366, 461-464 (1993).
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
-
37
-
-
33645472504
-
New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen
-
Hansen, M., Hsu, A. L., Dillin, A. & Kenyon, C. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet. 1, 119-128 (2005).
-
(2005)
PLoS Genet.
, vol.1
, pp. 119-128
-
-
Hansen, M.1
Hsu, A.L.2
Dillin, A.3
Kenyon, C.4
-
38
-
-
34447530305
-
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
-
Dietzl, G. et al. A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448, 151-156 (2007).
-
(2007)
Nature
, vol.448
, pp. 151-156
-
-
Dietzl, G.1
-
39
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner, S. The genetics of Caenorhabditis elegans. Genetics 77, 71-94 (1974).
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
40
-
-
0035941485
-
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
-
Timmons, L., Court, D. L. & Fire, A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene 263, 103-112 (2001).
-
(2001)
Gene
, vol.263
, pp. 103-112
-
-
Timmons, L.1
Court, D.L.2
Fire, A.3
-
41
-
-
78049441103
-
Novel EGF pathway regulators modulate C. Elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation
-
Iwasa, H., Yu, S., Xue, J. & Driscoll, M. Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation. Aging Cell 9, 490-505 (2010).
-
(2010)
Aging Cell
, vol.9
, pp. 490-505
-
-
Iwasa, H.1
Yu, S.2
Xue, J.3
Driscoll, M.4
-
42
-
-
70449529855
-
Induction of autophagy by spermidine promotes longevity
-
Eisenberg, T. et al. Induction of autophagy by spermidine promotes longevity. Nat. Cell Biol. 11, 1305-1314 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1305-1314
-
-
Eisenberg, T.1
-
43
-
-
77951020823
-
The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1
-
Heeren, G. et al. The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1. Aging 1, 622-636 (2009).
-
(2009)
Aging
, vol.1
, pp. 622-636
-
-
Heeren, G.1
-
44
-
-
0030854205
-
Mutants in the Saccharomyces cerevisiae RAS2 gene influence life span, cytoskeleton, and regulation of mitosis
-
Pichová, A., Vondráková, D. & Breitenbach, M. Mutants in the Saccharomyces cerevisiae RAS2 gene influence life span, cytoskeleton, and regulation of mitosis. Can. J. Microbiol. 43, 774-781 (1997).
-
(1997)
Can. J. Microbiol.
, vol.43
, pp. 774-781
-
-
Pichová, A.1
Vondráková, D.2
Breitenbach, M.3
-
45
-
-
59649120058
-
RNA cytosine methylation analysis by bisulfite sequencing
-
Schaefer, M., Pollex, T., Hanna, K. & Lyko, F. RNA cytosine methylation analysis by bisulfite sequencing. Nucleic Acids Res. 37, e12 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. e12
-
-
Schaefer, M.1
Pollex, T.2
Hanna, K.3
Lyko, F.4
-
46
-
-
77958091707
-
Detection of cytosine methylation in RNA using bisulfite sequencing
-
pdb.prot5505-pdb.prot5505
-
Pollex, T., Hanna, K. & Schaefer, M. Detection of cytosine methylation in RNA using bisulfite sequencing. Cold Spring Harb. Protoc. 2010, pdb.prot5505-pdb.prot5505 (2010).
-
(2010)
Cold Spring Harb. Protoc. 2010
-
-
Pollex, T.1
Hanna, K.2
Schaefer, M.3
-
47
-
-
0014757386
-
A general method applicable to the search for similarities in the amino acid sequence of two proteins
-
Needleman, S. B. & Wunsch, C. D. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J. Mol. Biol. 48, 443-453 (1970).
-
(1970)
J. Mol. Biol.
, vol.48
, pp. 443-453
-
-
Needleman, S.B.1
Wunsch, C.D.2
-
48
-
-
0033862288
-
Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome
-
Velichutina, I., Dresios, J. & Hong, J. Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome. RNA 6, 1174-1184 (2000).
-
(2000)
RNA
, vol.6
, pp. 1174-1184
-
-
Velichutina, I.1
Dresios, J.2
Hong, J.3
-
49
-
-
0035964256
-
A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition
-
Bayfield, M., Dahlberg, E., Schulmeister, U., Dorner, S. & Barta, A. A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition. Proc. Natl Acad. Sci. USA 98, 10096-10101 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 10096-10101
-
-
Bayfield, M.1
Dahlberg, E.2
Schulmeister, U.3
Dorner, S.4
Barta, A.5
-
50
-
-
0031696584
-
Metal ion probing of rRNAs: Evidence for evolutionarily conserved divalent cation binding pockets
-
Polacek, N. & Barta, A. Metal ion probing of rRNAs: evidence for evolutionarily conserved divalent cation binding pockets. RNA 4, 1282-1294 (1998).
-
(1998)
RNA
, vol.4
, pp. 1282-1294
-
-
Polacek, N.1
Barta, A.2
-
51
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Smyth, G. K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3, Article3 (2004).
-
(2004)
Stat. Appl. Genet. Mol. Biol.
, vol.3
, pp. Article3
-
-
Smyth, G.K.1
-
52
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102, 15545-15550 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
|