The relationship between target-class and the physicochemical properties of antibacterial drugs

Bioorganic and Medicinal Chemistry

Volumn 23, Issue 16, 2015, Pages 5218-5224

  Mugumbate, Grace ^a   Overington, John P ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Antibacterials; Drug targets; Physicochemical properties; Ribosome

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; RIBONUCLEOPROTEIN; RIBOSOME PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG CLASSIFICATION; DRUG DETERMINATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; LIPOPHILICITY; MOLECULAR WEIGHT; NONHUMAN; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; POLARITY; PRACTICE GUIDELINE; PROTEIN TARGETING; ANIMAL; BACTERIAL INFECTIONS; BACTERIUM; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; HUMAN; METABOLISM; MOLECULARLY TARGETED THERAPY; PROCEDURES;

BACTERIA (MICROORGANISMS);

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; BACTERIAL PROTEINS; DRUG DISCOVERY; HUMANS; MOLECULAR TARGETED THERAPY;

EID: 84938957955     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2015.04.063     Document Type: Article

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