B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production

European Journal of Immunology

Volumn 45, Issue 8, 2015, Pages 2243-2251

  Khmaladze, Ia ^a   Saxena, Amit ^a   Nandakumar, Kutty Selva ^a   Holmdahl, Rikard ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Arthritis; Auto reactive B cells; Autoantibodies; Epitope spreading; ROS

Indexed keywords

AUTOANTIBODY; EPITOPE; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G2C; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; NEUTROPHIL CYTOSOLIC FACTOR 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; BONE EROSION; CELL SPREADING; DISEASE COURSE; GENE MUTATION; GENETIC SUSCEPTIBILITY; GERMINAL CENTER; HISTOPATHOLOGY; INFLAMMATION; MALE; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SOMATIC HYPERMUTATION; T LYMPHOCYTE; ANIMAL; EXPERIMENTAL ARTHRITIS; GENETICS; IMMUNOLOGY; MUTATION; PATHOLOGY;

ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOANTIBODIES; B-LYMPHOCYTES; EPITOPES, B-LYMPHOCYTE; GERMINAL CENTER; MALE; MICE; MUTATION; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; T-LYMPHOCYTES;

EID: 84938955513     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201545518     Document Type: Article

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