IKZF1, a new susceptibility gene for cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement

Journal of Allergy and Clinical Immunology

Volumn 135, Issue 6, 2015, Pages 1538-1545.e17

  Ueta, Mayumi ^a,b,c   Sawai, Hiromi ^c   Sotozono, Chie ^a   Hitomi, Yuki ^c   Kaniwa, Nahoko ^d   Kim, Mee Kum ^e   Seo, Kyoung Yul ^f   Yoon, Kyung Chul ^g   Joo, Choun Ki ^h   Kannabiran, Chitra ⁱ   Wakamatsu, Tais Hitomi ^j   Sangwan, Virender ⁱ   Rathi, Varsha ⁱ   Basu, Sayan ⁱ   Ozeki, Takeshi ^k   Mushiroda, Taisei ^k   Sugiyama, Emiko ^d   Maekawa, Keiko ^d   Nakamura, Ryosuke ^d   Aihara, Michiko ^l   Matsunaga, Kayoko ^m   Sekine, Akihiro ⁿ   Gomes, José Álvaro Pereira ^j   Hamuro, Junji ^a   Saito, Yoshiro ^d   Kubo, Michiaki ^k   Kinoshita, Shigeru ^a   Tokunaga, Katsushi ^c   more..

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b DOSHISHA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^e Seoul National University   (South Korea)

^f Yonsei University College of Medicine   (South Korea)

^g Chonnam National University   (South Korea)

^h The Catholic University of Korea   (South Korea)

ⁱ L V PRASAD EYE INSTITUTE   (India)

^j FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^k Institute of Physical and Chemical Research   (Japan)

^l YOKOHAMA CITY UNIVERSITY   (Japan)

^m FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁿ KYOTO UNIVERSITY   (Japan)

more..

Author keywords

alternative splicing; cold medicine; genome wide association study; IKZF1; severe mucosal involvement; Stevens Johnson syndrome; toxic epidermal necrolysis

Indexed keywords

RNA ISOFORM; HLA A ANTIGEN; IKAROS TRANSCRIPTION FACTOR; IKZF1 PROTEIN, HUMAN; ISOPROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; RESPIRATORY TRACT AGENT;

ADULT; ALTERNATIVE RNA SPLICING; AMINO ACID SUBSTITUTION; ARTICLE; BRAZILIAN; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; IKZF1 GENE; INDIAN; JAPANESE (PEOPLE); KOREAN (PEOPLE); MAJOR CLINICAL STUDY; MALE; MUCOSAL DISEASE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEVERE MUCOSAL INVOLVEMENT; SINGLE NUCLEOTIDE POLYMORPHISM; STEVENS JOHNSON SYNDROME; TOXIC EPIDERMAL NECROLYSIS; ADOLESCENT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CASE CONTROL STUDY; CAUCASIAN; DRUG EFFECTS; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MIDDLE AGED; MOUTH MUCOSA; PATHOLOGY; RISK; STEVENS-JOHNSON SYNDROME;

ADOLESCENT; ADULT; AGED; ALTERNATIVE SPLICING; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HLA-A ANTIGENS; HUMANS; IKAROS TRANSCRIPTION FACTOR; MALE; MIDDLE AGED; MOUTH MUCOSA; MULTI-INGREDIENT COLD, FLU, AND ALLERGY MEDICATIONS; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS; STEVENS-JOHNSON SYNDROME;

EID: 84938928171     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.12.1916     Document Type: Article

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