Circadian modulation in the intestinal absorption of P-glycoprotein substrates in monkeys

Molecular Pharmacology

Volumn 88, Issue 1, 2015, Pages 29-37

  Iwasaki, Masaru ^a   Koyanagi, Satoru ^b   Suzuki, Norio ^a   Katamune, Chiharu ^b   Matsunaga, Naoya ^b   Watanabe, Nobuaki ^a   Takahashi, Masayuki ^a   Izumi, Takashi ^a   Ohdo, Shigehiro ^b  

^a DAIICHI SANKYO CO   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; BREAST CANCER RESISTANCE PROTEIN; CYTOCHROME P450 3A; ETOPOSIDE; MESSENGER RNA; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PARACETAMOL; QUINIDINE; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK; CIRCADIAN RHYTHM SIGNALING PROTEIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DIURNAL ANIMAL; DNA FLANKING REGION; DRUG ABSORPTION; DRUG DISPOSITION; ELIMINATION HALF-LIFE; INTESTINE ABSORPTION; INTESTINE EPITHELIUM CELL; MACACA FASCICULARIS; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMALL INTESTINE; SUPRACHIASMATIC NUCLEUS; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; ANATOMY AND HISTOLOGY; ANIMAL; DRUG EFFECTS; GENETICS; JEJUNUM; LIVER; METABOLISM; PHYSIOLOGY;

ACETAMINOPHEN; ANIMALS; CIRCADIAN CLOCKS; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM SIGNALING PEPTIDES AND PROTEINS; ETOPOSIDE; INTESTINAL ABSORPTION; JEJUNUM; LIVER; MACACA FASCICULARIS; MALE; P-GLYCOPROTEIN; QUINIDINE; SUPRACHIASMATIC NUCLEUS;

EID: 84938889996     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.114.096735     Document Type: Article

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