Measured prenatal and estimated postnatal levels of polychlorinated biphenyls (PCBs) and ADHD-related behaviors in 8-year-old children

Environmental Health Perspectives

Volumn 123, Issue 9, 2015, Pages 888-894

  Verner, Marc André ^a,b   Hart, Jaime E ^a,c   Sagiv, Sharon K ^d   Bellinger, David C ^a,c   Altshul, Larisa M ^c,e   Korrick, Susan A ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^e Environmental Health & Engineering Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2, 2', 4, 4', 5, 5' HEXACHLOROBIPHENYL; LIPID; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; UNCLASSIFIED DRUG; POLLUTANT;

ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; BREAST FEEDING; CHILD; CORD SERUM; ENVIRONMENTAL EXPOSURE; FEMALE; FETOMATERNAL TRANSFUSION; GAS CHROMATOGRAPHY; HUMAN; HYPERACTIVITY; IMPULSIVENESS; MODEL; PHARMACOKINETIC MODEL; PRIORITY JOURNAL; QUESTIONNAIRE; SCHOOL CHILD; SCORING SYSTEM; SENSITIVITY ANALYSIS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BLOOD; INFANT; LONGITUDINAL STUDY; MALE; MASSACHUSETTS; MATERNAL EXPOSURE; POLLUTANT; PREGNANCY; PRENATAL EXPOSURE; PRESCHOOL CHILD;

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BREAST FEEDING; CHILD; CHILD, PRESCHOOL; ENVIRONMENTAL POLLUTANTS; FEMALE; HUMANS; INFANT; LONGITUDINAL STUDIES; MALE; MASSACHUSETTS; MATERNAL EXPOSURE; POLYCHLORINATED BIPHENYLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 84938876688     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1408084     Document Type: Article

References (32)

1. American Psychiatric Association. 1994. Diagnostic and Statistical Manual of Mental Disorders. DSM-IV. 4th ed. Washington, DC:American Psychiatric Association.
2. Ayotte P, Muckle G, Jacobson JL, Jacobson SW, Dewailly É, Inuit Cohort Study. 2003. Assessment of pre- and postnatal exposure to polychlorinated biphenyls: lessons from the Inuit Cohort Study. Environ Health Perspect 111:1253–1258; doi:10.1289/ehp.6054.
3. Beyerlein A. 2014. Quantile regression—opportunities and challenges from a user’s perspective. Am J Epidemiol 180(3):330–331.
4. Butte NF, Ellis KJ, Wong WW, Hopkinson JM, Smith EO. 2003. Composition of gestational weight gain impacts maternal fat retention and infant birth weight. Am J Obstet Gynecol 189(5):1423–1432.
5. Caldwell BM, Bradley RH. 1984. HOME Observation for Measurement of the Environment. Revised ed. Little Rock, AR:University of Arkansas at Little Rock.
6. Choi AL, Levy JI, Dockery DW, Ryan LM, Tolbert PE, Altshul LM, et al. 2006. Does living near a Superfund site contribute to higher polychlorinated biphenyl (PCB) exposure? Environ Health Perspect 114:1092–1098; doi:10.1289/ehp.8827.
7. Conners CK. 1997. Conners’ Rating Scales–Revised: Technical Manual. North Tonawanda, NY:Multi- Health Systems.
8. Eubig PA, Aguiar A, Schantz SL. 2010. Lead and PCBs as risk factors for attention deficit/hyperactivity disorder. Environ Health Perspect 118:1654–1667; doi:10.1289/ehp.0901852.
9. Fritsche E, Cline JE, Nguyen NH, Scanlan TS, Abel J. 2005. Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: clue for involvement of thyroid hormone receptors. Environ Health Perspect 113:871–876; doi:10.1289/ehp.7793.
10. Holene E, Nafstad I, Skaare JU, Sagvolden T. 1998. Behavioural hyperactivity in rats following postnatal exposure to sub-toxic doses of polychlorinated biphenyl congeners 153 and 126. Behav Brain Res 94(1):213–224.
11. Jacobson JL, Jacobson SW. 2003. Prenatal exposure to polychlorinated biphenyls and attention at school age. J Pediatr 143(6):780–788.
12. Jacobson JL, Jacobson SW, Humphrey HE. 1990. Effects of exposure to PCBs and related compounds on growth and activity in children. Neurotoxicol Teratol 12(4):319–326.
13. Julvez J, Ribas-Fitó N, Forns M, Garcia-Esteban R, Torrent M, Sunyer J. 2007. Attention behaviour and hyperactivity at age 4 and duration of breast- feeding. Acta Paediatr 96(6):842–847.
14. Koenker R, Bassett G Jr. 1978. Regression Quantiles. Econometrica 46(1):33–50.
15. Korrick SA, Altshul LM, Tolbert PE, Burse VW, Needham LL, Monson RR. 2000. Measurement of PCBs, DDE, and hexachlorobenzene in cord blood from infants born in towns adjacent to a PCB-contaminated waste site. J Expo Anal Environ Epidemiol 10(6 pt 2):743–754.
16. Lanting CI, Fidler V, Huisman M, Boersma ER. 1998. Determinants of polychlorinated biphenyl levels in plasma from 42-month-old children. Arch Environ Contam Toxicol 35(1):135–139.
17. Latimer K, Wilson P, Kemp J, Thompson L, Sim F, Gillberg C, et al. 2012. Disruptive behaviour disorders: a systematic review of environmental antenatal and early years risk factors. Child Care Health Dev 38(5):611–628.
18. Longnecker MP, Wolff MS, Gladen BC, Brock JW, Grandjean P, Jacobson JL, et al. 2003. Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment. Environ Health Perspect 111:65–70; doi:10.1289/ehp.5463.
19. Miranda ML, Kim D, Reiter J, Overstreet Galeano MA, Maxson P. 2009. Environmental contributors to the achievement gap. Neurotoxicology 30(6):1019–1024.
20. Muckle G, Ayotte P, Dewailly É, Jacobson SW, Jacobson JL. 2001. Prenatal exposure of the northern Québec Inuit infants to environmental contaminants. Environ Health Perspect 109:1291–1299.
21. Patandin S, Weisglas-Kuperus N, de Ridder MA, Koopman-Esseboom C, van Staveren WA, van der Paauw CG, et al. 1997. Plasma polychlorinated biphenyl levels in Dutch preschool children either breast-fed or formula-fed during infancy. Am J Public Health 87(10):1711–1714.
22. Plusquellec P, Muckle G, Dewailly E, Ayotte P, Bégin G, Desrosiers C, et al. 2010. The relation of environmental contaminants exposure to behavioral indicators in Inuit preschoolers in Arctic Quebec. Neurotoxicology 31(1):17–25.
23. Rasmussen KM, Yaktine AL, eds. 2009. Weight Gain During Pregnancy: Reexamining the Guidelines. Committee to Reexamine IOM Pregnancy Weight Guidelines, Food and Nutrition Board and Board on Children, Youth, and Families. Washington, DC:National Academies Press. Available: http://iom.nationalacademies.org/en/Reports/2009/ Weight-Gain-During-Pregnancy-Reexamining-the-Guidelines.aspx [accessed 20 February 2013].
24. Rice DC. 2000. Parallels between attention deficit hyperactivity disorder and behavioral deficits produced by neurotoxic exposure in monkeys. Environ Health Perspect 108(suppl 3):405–408.
25. Rice D, Barone S Jr. 2000. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 108(suppl 3):511–533.
26. Ritter R, Scheringer M, MacLeod M, Moeckel C, Jones KC, Hungerbühler K. 2011. Intrinsic human elimination half-lives of polychlorinated biphenyls derived from the temporal evolution of cross- sectional biomonitoring data from the United Kingdom. Environ Health Perspect 119:225–231; doi:10.1289/ehp.1002211.
27. Sagiv SK, Thurston SW, Bellinger DC, Tolbert PE, Altshul LM, Korrick SA. 2010. Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged children. Am J Epidemiol 171(5):593–601.
28. Sharp SI, McQuillin A, Gurling HM. 2009. Genetics of attention-deficit hyperactivity disorder (ADHD). Neuropharmacology 57(7–8):590–600.
29. Tripp G, Schaughency EA, Clarke B. 2006. Parent and teacher rating scales in the evaluation of attentiondeficit hyperactivity disorder: contribution to diagnosis and differential diagnosis in clinically referred children. J Dev Behav Pediatr 27(3):209–218.
30. Verner MA, Plusquellec P, Muckle G, Ayotte P, Dewailly É, Jacobson SW, et al. 2010. Alteration of infant attention and activity by polychlorinated biphenyls: unravelling critical windows of susceptibility using physiologically based pharmacokinetic modeling. Neurotoxicology 31(5):424–431.
31. Verner MA, Sonneborn D, Lancz K, Muckle G, Ayotte P, Dewailly É, et al. 2013. Toxicokinetic modeling of persistent organic pollutant levels in blood from birth to 45 months of age in longitudinal birth cohort studies. Environ Health Perspect 121:131–137; doi:10.1289/ehp.1205552.
32. Vreugdenhil HJ, Slijper FM, Mulder PG, Weisglas- Kuperus N. 2002. Effects of perinatal exposure to PCBs and dioxins on play behavior in Dutch children at school age. Environ Health Perspect 110:A593–A598.