Behavioural hyperactivity in rats following postnatal exposure to sub- toxic doses of polychlorinated biphenyl congeners 153 and 126

Behavioural Brain Research

Volumn 94, Issue 1, 1998, Pages 213-224

  Holene, Edel ^a   Nafstad, Inger ^a   Skaare, Janneche Utne ^a,b   Sagvolden, Terje ^c  

^a Microbiol Food Hyg   (Norway)

^b NORWEGIAN VETERINARY INSTITUTE   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Hyperactivity; Operant behaviour; PCB; PCB congener 126; PCB congener 153; Postnatal PCB exposure; Rats

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; CORN OIL; DRUG VEHICLE; HEXACHLOROBIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION DEFICIT DISORDER; BREAST FEEDING; BREAST MILK; CONTROLLED STUDY; HYPERACTIVITY; INSTRUMENTAL CONDITIONING; MALE; NEUROTOXICITY; NEWBORN; NONHUMAN; PERINATAL DRUG EXPOSURE; PRIORITY JOURNAL; REINFORCEMENT; RESPONSE TIME; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; ANIMALS, NEWBORN; AROUSAL; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BEHAVIOR, ANIMAL; CONDITIONING, OPERANT; FEMALE; MALE; MOTOR ACTIVITY; POLYCHLORINATED BIPHENYLS; PREGNANCY; RATS; REACTION TIME; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032126298     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(97)00181-2     Document Type: Article

References (30)

1. Agrawal A.K., Tilson H.A., Bondy S.C. 3,4,3′,4′-Tetrachlorobiphenyl given to mice prenatally produces long-term decrease in striatal dopamine and receptor binding sites in the caudate nucleus. Toxicol Lett. 7:1981;417-424.
2. Alder S. Behavioral teratology. Zbinden G., Cuomo V., Racagni G., Weiss B. Application of Behavioral Pharmacology in Toxicology. 1983;57-66 Raven, New York.
3. Berger DF, Sagvolden T Sex differences in visual discrimination behaviour in an animal model of attention deficit hyperactivity disorder. Behav Brain Res. 94:1998;73-82.
4. Bernhoft A., Nafstad I., Engen P., Skaare J.U. Effects of pre and postnatal exposure to 3,3′,4,4′,5-pentachlorobiphenyl on physical development, neurobehavior and xenobiotic metabolizing enzymes in rats. Environ Toxicol Chem. 13:1994;1589-1597.
5. Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:1976;248-254.
6. Brevik E.M. Gas chromatographic method for determination of organochlorine pesticides in human milk. Bull Environ Contam. 19:1978;281-286.
7. Brouwer A. et al. Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants. Environ Toxicol Pharmacol Sect. 293:1995;1-40.
8. Chen Y-C.J., Guo Y-L., Hsu C-C., Rogan W.J. Cognitive development of Yu-Chen (oil disease) children prenatally exposed to heat-degraded PCBs. J Am Med Assoc. 268:1992;3213-3218.
9. Eriksson P. Effects of 3,3′,4,4′-tetrachlorobiphenyl in the brain of the neonatal mouse. Toxicology. 49:1988;43-48.
10. Eriksson P., Lundkvist U., Fredriksson A. Neonatal exposure to 3,3′,4,4′-tetrachloro-biphenyl: changes in spontaneous behaviour and cholinergic muscarinic receptors in the adult mouse. Toxicology. 69:1991;27-34.
11. Habig W.H., Pabst M.J., Jacoby W.B. Glutathion-S-transferase. The first enzyme step in mercapturic acid formation. J Biol Chem. 249:1974;7130-7139.
12. Holene E., Nafstad I., Skaare J.U., Bernhoft A., Engen P., Sagvolden T. Behavioral effects of pre and postnatal exposure to individual polychlorinated biphenyl congeners in rats. Environ Toxicol Chem. 14:1995;967-976.
13. Jacobsen J.L., Jacobsen S.W., Humphrey H.E.B. Effects of exposure to PCB and related compounds on growth and activity in children. Neurotoxicol Teratol. 12:1990;319-326.
14. Klotz A.V., Stegeman J.J., Walsh C. An alternative 7-ethoxyresorufine-O-deethylase activity assay: a continuous visible spectrophotometric method for measurement of cytochrome P-450 monooxygenase activity. Anal Biochem. 140:1984;138-145.
15. Kodavanti P.R.S., Shin D-S., Tilson H.A., Harry G.J. Comparative effects of two polychlorinated biphenyl congeners on calcium homeostasis in rat cerebellar granule cells. Toxicol Appl Pharmacol. 126:1993;97-106.
16. Lilienthal H., Winnecke G. Sensitive periods for behavioral toxicity of polychlorinated biphenyls: Determination by cross-fostering in rats. Fundam Appl Toxicol. 17:1991;368-375.
17. Maier W.E., Rao P., Kodavanti S., Harry G.J., Tilson H.A. Sensitivity of adenosine triphosphatases in different brain regions to polychlorinated biphenyl congeners. J Appl Toxicol. 14(3):1994;225-229.
18. McFarland V.A., Clarke J.U. Environmental occurrence, abundance and potential toxicity of polychlorinated biphenyl congeners: Considerations for a congener-specific analysis. Environ Health Perspect. 81:1989;225-239.
19. Moldenke A.F., Terriere L.C. Cytochrome P-450 in insects. 3. Increase in substrate binding by microsomes from phenobarbital-induced house flies. Pestic Biochem. 16:1981;222-230.
20. Pantaleoni G., Fanini D., Sponta A.M., Palumbo G., Giorgi R., Adams P.M. Effects of maternal exposure to polychlorinated biphenyls (PCBs) on F1 generation behavior in the rat. Fundam Appl Toxicol. 11:1988;440-449.
21. Rushmore T.H., Pickett C.B. Regulation of glutathione-S-transferase ya subunit gene expression by planar aromatic compounds. Hayes J.D., Pickett C.B., Mantle T.J. Glutathione-S-Transferases and Drug Resistance. 1990;157-164 Taylor and Francis, London.
22. Safe S.H. Polychlorinated biphenyls (PCBs): Environmental impact, biochemical and toxic responses and implications for risk assessment. Crit Rev Toxicol. 24(2):1994;87-149.
23. Safe S.H., Astroff B., Harris M., Zacharewski T., Dickerson R., Romkes M. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antioestrogens: Characterization and mechanism of action. Pharmacol Toxicol. 69:1991;400-409.
24. Sagvolden T, Aase H, Zeiner P, Berger DF. Altered reinforcement mechanisms in attention deficit hyperactivity disorder: Hyperactivity may be acquired. Behav Brain Res. 94:1998;61-71.
25. Schantz S.L., Moshtaghian J., Ness D.K. Spatial learning deficits in adult rats exposed to ortho-substituted PCB congeners during gestation and lactation. Fundam Appl Toxicol. 26:1995;117-126.
26. Seegal R.F., Bush B., Brosch K.O. Comparison of effects of Aroclors 1016 and 1260 on non-human primate catecholamine function. Toxicology. 66:1991;145-163.
27. Seegal R.F., Bush B., Brosch K.O. Decreases in dopamine concentrations in adult, non-human primate brain persist following removal from polychlorinated biphenyls. Toxicology. 86:1994;71-78.
28. Shain W., Bush B., Seegal R. Neurotoxicity of polychlorinated biphenyls: Structure-activity relationship of individual congeners. Toxicol Appl Pharmacol. 11:1991;33-42.
29. StatSoft. STATISTICA for Windows, Release 4.0. Tulsa, OK: StatSoft, 1993.
30. Tilson H.A., Davis G.J., McLachlan J.A., Lucier G.W. The effects of polychlorinated biphenyls given prenatally on the neurobehavioral development of mice. Environ Res. 18:1979;466-474.