메뉴 건너뛰기




Volumn 304, Issue , 2015, Pages 368-377

Noise-induced damage to ribbon synapses without permanent threshold shifts in neonatal mice

Author keywords

Cochlea; Neonatal mice; Noise; Permanent threshold shift; Ribbon synapse

Indexed keywords

ACTION POTENTIAL AMPLITUDE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD; COCHLEA; CONTROLLED STUDY; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING ACUITY; KUNMING MOUSE; LATENT PERIOD; MOUSE; NEWBORN; NOISE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RIBBON SYNAPSE; SYNAPSE; ANIMAL; DISEASE MODEL; FEMALE; MALE; NOISE INJURY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION;

EID: 84938869288     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.07.066     Document Type: Article
Times cited : (29)

References (64)
  • 1
    • 77954363488 scopus 로고    scopus 로고
    • Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target
    • Albrecht P., Lewerenz J., Dittmer S., Noack R., Maher P., Methner A. Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target. CNS Neurol Disord Drug Targets 2010, 9:373-382.
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 373-382
    • Albrecht, P.1    Lewerenz, J.2    Dittmer, S.3    Noack, R.4    Maher, P.5    Methner, A.6
  • 2
    • 77953204546 scopus 로고    scopus 로고
    • Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons
    • Buran B.N., Strenzke N., Neef A., Gundelfinger E.D., Moser T., Liberman M.C. Onset coding is degraded in auditory nerve fibers from mutant mice lacking synaptic ribbons. J Neurosci 2010, 30:7587-7597.
    • (2010) J Neurosci , vol.30 , pp. 7587-7597
    • Buran, B.N.1    Strenzke, N.2    Neef, A.3    Gundelfinger, E.D.4    Moser, T.5    Liberman, M.C.6
  • 3
    • 84907068893 scopus 로고    scopus 로고
    • Functional and structural changes throughout the auditory system following congenital and early-onset deafness: implications for hearing restoration
    • Butler B.E., Lomber S.G. Functional and structural changes throughout the auditory system following congenital and early-onset deafness: implications for hearing restoration. Front Syst Neurosci 2013, 7:92.
    • (2013) Front Syst Neurosci , vol.7 , pp. 92
    • Butler, B.E.1    Lomber, S.G.2
  • 4
    • 34547635242 scopus 로고    scopus 로고
    • Plasticity of synaptic endings in the cochlear nucleus following noise-induced hearing loss is facilitated in the adult FGF2 overexpressor mouse
    • D'Sa C., Gross J., Francone V.P., Morest D.K. Plasticity of synaptic endings in the cochlear nucleus following noise-induced hearing loss is facilitated in the adult FGF2 overexpressor mouse. Eur J Neurosci 2007, 26:666-680.
    • (2007) Eur J Neurosci , vol.26 , pp. 666-680
    • D'Sa, C.1    Gross, J.2    Francone, V.P.3    Morest, D.K.4
  • 5
    • 0016937549 scopus 로고
    • Development of absolute auditory thresholds in the house mouse (Mus musculus)
    • Ehret G. Development of absolute auditory thresholds in the house mouse (Mus musculus). J Am Audiol Soc 1976, 1:179-184.
    • (1976) J Am Audiol Soc , vol.1 , pp. 179-184
    • Ehret, G.1
  • 6
    • 0021783258 scopus 로고
    • Behavioural studies on auditory development in mammals in relation to higher nervous system functioning
    • Ehret G. Behavioural studies on auditory development in mammals in relation to higher nervous system functioning. Acta Otolaryngol Suppl 1985, 421:31-40.
    • (1985) Acta Otolaryngol Suppl , vol.421 , pp. 31-40
    • Ehret, G.1
  • 7
    • 0021783258 scopus 로고
    • Behavioural studies on auditory development in mammals in relation to higher nervous system functioning. [Review] [40 refs]
    • Ehret G. Behavioural studies on auditory development in mammals in relation to higher nervous system functioning. [Review] [40 refs]. Acta Otolaryngol Suppl 1985, 421:31-40.
    • (1985) Acta Otolaryngol Suppl , vol.421 , pp. 31-40
    • Ehret, G.1
  • 8
    • 0027106723 scopus 로고
    • The role of calcium in hair cell transduction
    • Fettiplace R. The role of calcium in hair cell transduction. Soc Gen Physiol Ser 1992, 47:343-356.
    • (1992) Soc Gen Physiol Ser , vol.47 , pp. 343-356
    • Fettiplace, R.1
  • 9
    • 22144466901 scopus 로고    scopus 로고
    • Time and intensity coding at the hair cell's ribbon synapse
    • Fuchs P.A. Time and intensity coding at the hair cell's ribbon synapse. J Physiol 2005, 566:7-12.
    • (2005) J Physiol , vol.566 , pp. 7-12
    • Fuchs, P.A.1
  • 11
    • 84933674030 scopus 로고    scopus 로고
    • Molecular basis of hair cell loss
    • Furness D.N. Molecular basis of hair cell loss. Cell Tissue Res 2015.
    • (2015) Cell Tissue Res
    • Furness, D.N.1
  • 12
    • 0034554777 scopus 로고    scopus 로고
    • Exacerbation of noise-induced hearing loss in mice lacking the glutamate transporter GLAST
    • Hakuba N., Koga K., Gyo K., Usami S.I., Tanaka K. Exacerbation of noise-induced hearing loss in mice lacking the glutamate transporter GLAST. J Neurosci 2000, 20:8750-8753.
    • (2000) J Neurosci , vol.20 , pp. 8750-8753
    • Hakuba, N.1    Koga, K.2    Gyo, K.3    Usami, S.I.4    Tanaka, K.5
  • 13
    • 0034576134 scopus 로고    scopus 로고
    • Development of the ear and hearing
    • Hall J.W. Development of the ear and hearing. J Perinatol 2000, 20:S12-20.
    • (2000) J Perinatol , vol.20 , pp. S12-20
    • Hall, J.W.1
  • 14
    • 84861185914 scopus 로고    scopus 로고
    • Changes in projections to the inferior colliculus following early hearing loss in rats
    • Hatano M., Ito M., Yoshizaki T., Kelly J.B. Changes in projections to the inferior colliculus following early hearing loss in rats. Hear Res 2012, 287:57-66.
    • (2012) Hear Res , vol.287 , pp. 57-66
    • Hatano, M.1    Ito, M.2    Yoshizaki, T.3    Kelly, J.B.4
  • 16
    • 84874591501 scopus 로고    scopus 로고
    • Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse
    • Jing Z., Rutherford M.A., Takago H., Frank T., Fejtova A., Khimich D., Moser T., Strenzke N. Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse. J Neurosci 2013, 33:4456-4467.
    • (2013) J Neurosci , vol.33 , pp. 4456-4467
    • Jing, Z.1    Rutherford, M.A.2    Takago, H.3    Frank, T.4    Fejtova, A.5    Khimich, D.6    Moser, T.7    Strenzke, N.8
  • 18
    • 70449643246 scopus 로고    scopus 로고
    • Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss
    • Kujawa S.G., Liberman M.C. Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss. J Neurosci 2009, 29:14077-14085.
    • (2009) J Neurosci , vol.29 , pp. 14077-14085
    • Kujawa, S.G.1    Liberman, M.C.2
  • 19
    • 84920564833 scopus 로고    scopus 로고
    • Questionable sound exposure outside of the womb: frequency analysis of environmental noise in the neonatal intensive care unit
    • Lahav A. Questionable sound exposure outside of the womb: frequency analysis of environmental noise in the neonatal intensive care unit. Acta Paediatr 2014.
    • (2014) Acta Paediatr
    • Lahav, A.1
  • 21
    • 0018875841 scopus 로고
    • Sensitive period to acoustic trauma in the rat pup cochlea. Histological findings
    • Lenoir M., Pujol R. Sensitive period to acoustic trauma in the rat pup cochlea. Histological findings. Acta Otolaryngol 1980, 89:317-322.
    • (1980) Acta Otolaryngol , vol.89 , pp. 317-322
    • Lenoir, M.1    Pujol, R.2
  • 22
    • 59649108242 scopus 로고    scopus 로고
    • Synergistic ototoxicity due to noise exposure and aminoglycoside antibiotics
    • Li H., Steyger P.S. Synergistic ototoxicity due to noise exposure and aminoglycoside antibiotics. Noise Health 2009, 11:26-32.
    • (2009) Noise Health , vol.11 , pp. 26-32
    • Li, H.1    Steyger, P.S.2
  • 23
    • 80054116266 scopus 로고    scopus 로고
    • Primary neural degeneration in the Guinea pig cochlea after reversible noise-induced threshold shift
    • Lin H.W., Furman A.C., Kujawa S.G., Liberman M.C. Primary neural degeneration in the Guinea pig cochlea after reversible noise-induced threshold shift. J Assoc Res Otolaryngol 2011, 12:605-616.
    • (2011) J Assoc Res Otolaryngol , vol.12 , pp. 605-616
    • Lin, H.W.1    Furman, A.C.2    Kujawa, S.G.3    Liberman, M.C.4
  • 24
    • 84869838336 scopus 로고    scopus 로고
    • Silent damage of noise on cochlear afferent innervation in guinea pigs and the impact on temporal processing
    • Liu L., Wang H., Shi L., Almuklass A., He T., Aiken S., Bance M., Yin S., Wang J. Silent damage of noise on cochlear afferent innervation in guinea pigs and the impact on temporal processing. PLoS One 2012, 7:e49550.
    • (2012) PLoS One , vol.7 , pp. e49550
    • Liu, L.1    Wang, H.2    Shi, L.3    Almuklass, A.4    He, T.5    Aiken, S.6    Bance, M.7    Yin, S.8    Wang, J.9
  • 25
    • 79960227005 scopus 로고    scopus 로고
    • The development and evolution of a tonotopic organization in the cochlea
    • Manley G.A., Jones T.A. The development and evolution of a tonotopic organization in the cochlea. Hear Res 2011, 277:1-3.
    • (2011) Hear Res , vol.277 , pp. 1-3
    • Manley, G.A.1    Jones, T.A.2
  • 26
    • 79957936985 scopus 로고    scopus 로고
    • Development of tonotopy in the auditory periphery
    • Mann Z.F., Kelley M.W. Development of tonotopy in the auditory periphery. Hear Res 2011, 276:2-15.
    • (2011) Hear Res , vol.276 , pp. 2-15
    • Mann, Z.F.1    Kelley, M.W.2
  • 27
    • 0018564740 scopus 로고
    • Development and degeneration of hearing in the C57/b16 mouse: Relation of electrophysiologic responses from the round window and cochlear nucleus to cochlear anatomy and behavioral responses
    • Mikaelian D.O. Development and degeneration of hearing in the C57/b16 mouse: Relation of electrophysiologic responses from the round window and cochlear nucleus to cochlear anatomy and behavioral responses. Laryngoscope 1979, 89:1-15.
    • (1979) Laryngoscope , vol.89 , pp. 1-15
    • Mikaelian, D.O.1
  • 28
    • 0000848261 scopus 로고
    • Development of hearing in the normal CBA-J mouse. Correlation of physiological observations with behavioral responses and with cochlear anatomy
    • Mikaelian D.O., Ruben R.J. Development of hearing in the normal CBA-J mouse. Correlation of physiological observations with behavioral responses and with cochlear anatomy. Acta Otolaryngol 1965, 59:451-461.
    • (1965) Acta Otolaryngol , vol.59 , pp. 451-461
    • Mikaelian, D.O.1    Ruben, R.J.2
  • 30
    • 33748886717 scopus 로고    scopus 로고
    • Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse
    • Moser T., Neef A., Khimich D. Mechanisms underlying the temporal precision of sound coding at the inner hair cell ribbon synapse. J Physiol 2006, 576:55-62.
    • (2006) J Physiol , vol.576 , pp. 55-62
    • Moser, T.1    Neef, A.2    Khimich, D.3
  • 31
    • 84881374344 scopus 로고    scopus 로고
    • Review of hair cell synapse defects in sensorineural hearing impairment
    • Moser T., Predoehl F., Starr A. Review of hair cell synapse defects in sensorineural hearing impairment. Otol Neurotol 2013, 34:995-1004.
    • (2013) Otol Neurotol , vol.34 , pp. 995-1004
    • Moser, T.1    Predoehl, F.2    Starr, A.3
  • 32
    • 84938853395 scopus 로고
    • Research in human communication. Bethesda, MD: National Institute on Deafness and Other Communication Disorders
    • NIDCD (1995) Research in human communication. Bethesda, MD: National Institute on Deafness and Other Communication Disorders.
    • (1995)
  • 33
    • 33745079195 scopus 로고    scopus 로고
    • Structure and function of the hair cell ribbon synapse
    • Nouvian R., Beutner D., Parsons T.D., Moser T. Structure and function of the hair cell ribbon synapse. J Membr Biol 2006, 209:153-165.
    • (2006) J Membr Biol , vol.209 , pp. 153-165
    • Nouvian, R.1    Beutner, D.2    Parsons, T.D.3    Moser, T.4
  • 34
    • 78650527416 scopus 로고    scopus 로고
    • Cell death mechanisms and their implications in toxicology
    • Orrenius S., Nicotera P., Zhivotovsky B. Cell death mechanisms and their implications in toxicology. Toxicol Sci 2011, 119:3-19.
    • (2011) Toxicol Sci , vol.119 , pp. 3-19
    • Orrenius, S.1    Nicotera, P.2    Zhivotovsky, B.3
  • 35
    • 84938902680 scopus 로고    scopus 로고
    • Trends of the acoustic condition in an intensive care unit based on a long-term measurement
    • Park M., Vos P., Kohlrausch A., Oldenbeuving A.W. Trends of the acoustic condition in an intensive care unit based on a long-term measurement. J Acoust Soc Am 2014, 135:2403.
    • (2014) J Acoust Soc Am , vol.135 , pp. 2403
    • Park, M.1    Vos, P.2    Kohlrausch, A.3    Oldenbeuving, A.W.4
  • 36
    • 84885107063 scopus 로고    scopus 로고
    • Brief hearing loss disrupts binaural integration during two early critical periods of auditory cortex development
    • Polley D.B., Thompson J.H., Guo W. Brief hearing loss disrupts binaural integration during two early critical periods of auditory cortex development. Nat Commun 2013, 4:2547.
    • (2013) Nat Commun , vol.4 , pp. 2547
    • Polley, D.B.1    Thompson, J.H.2    Guo, W.3
  • 37
    • 0030980711 scopus 로고    scopus 로고
    • Synaptic repair mechanisms responsible for functional recovery in various cochlear pathologies
    • Puel J.L., d'Aldin C., Ruel J., Ladrech S., Pujol R. Synaptic repair mechanisms responsible for functional recovery in various cochlear pathologies. Acta Otolaryngol 1997, 117:214-218.
    • (1997) Acta Otolaryngol , vol.117 , pp. 214-218
    • Puel, J.L.1    d'Aldin, C.2    Ruel, J.3    Ladrech, S.4    Pujol, R.5
  • 38
    • 0032787079 scopus 로고    scopus 로고
    • Excitotoxicity, synaptic repair, and functional recovery in the mammalian cochlea: a review of recent findings
    • Pujol R., Puel J.L. Excitotoxicity, synaptic repair, and functional recovery in the mammalian cochlea: a review of recent findings. Ann N Y Acad Sci 1999, 884:249-254.
    • (1999) Ann N Y Acad Sci , vol.884 , pp. 249-254
    • Pujol, R.1    Puel, J.L.2
  • 39
    • 0025974763 scopus 로고
    • Glutamate neurotoxicity in the cochlea: a possible consequence of ischaemic or anoxic conditions occurring in ageing
    • Pujol R., Rebillard G., Puel J.L., Lenoir M., Eybalin M., Recasens M. Glutamate neurotoxicity in the cochlea: a possible consequence of ischaemic or anoxic conditions occurring in ageing. Acta Otolaryngol Suppl 1990, 476:32-36.
    • (1990) Acta Otolaryngol Suppl , vol.476 , pp. 32-36
    • Pujol, R.1    Rebillard, G.2    Puel, J.L.3    Lenoir, M.4    Eybalin, M.5    Recasens, M.6
  • 42
    • 84924714571 scopus 로고    scopus 로고
    • Development of the acoustic startle response in rats and its change after early acoustic trauma
    • Rybalko N., Chumak T., Bures Z., Popelar J., Suta D., Syka J. Development of the acoustic startle response in rats and its change after early acoustic trauma. Behav Brain Res 2015, 286:212-221.
    • (2015) Behav Brain Res , vol.286 , pp. 212-221
    • Rybalko, N.1    Chumak, T.2    Bures, Z.3    Popelar, J.4    Suta, D.5    Syka, J.6
  • 43
    • 84862638774 scopus 로고    scopus 로고
    • The auditory hair cell ribbon synapse: from assembly to function
    • Safieddine S., El-Amraoui A., Petit C. The auditory hair cell ribbon synapse: from assembly to function. Annu Rev Neurosci 2012, 35:509-528.
    • (2012) Annu Rev Neurosci , vol.35 , pp. 509-528
    • Safieddine, S.1    El-Amraoui, A.2    Petit, C.3
  • 44
    • 0020332550 scopus 로고
    • Sensitive periods of susceptibility to auditory trauma in mammals
    • Saunders J.C., Chen C.S. Sensitive periods of susceptibility to auditory trauma in mammals. Environ Health Perspect 1982, 44:63-66.
    • (1982) Environ Health Perspect , vol.44 , pp. 63-66
    • Saunders, J.C.1    Chen, C.S.2
  • 45
    • 71949109145 scopus 로고    scopus 로고
    • The making of synaptic ribbons: how they are built and what they do
    • Schmitz F. The making of synaptic ribbons: how they are built and what they do. Neuroscientist 2009, 15:611-624.
    • (2009) Neuroscientist , vol.15 , pp. 611-624
    • Schmitz, F.1
  • 46
    • 84870171980 scopus 로고    scopus 로고
    • Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells
    • Sheets L., Kindt K.S., Nicolson T. Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells. J Neurosci 2012, 32:17273-17286.
    • (2012) J Neurosci , vol.32 , pp. 17273-17286
    • Sheets, L.1    Kindt, K.S.2    Nicolson, T.3
  • 47
    • 84892609753 scopus 로고    scopus 로고
    • Ribbon synapse plasticity in the cochleae of Guinea pigs after noise-induced silent damage
    • Shi L., Liu L., He T., Guo X., Yu Z., Yin S., Wang J. Ribbon synapse plasticity in the cochleae of Guinea pigs after noise-induced silent damage. PLoS One 2013, 8:e81566.
    • (2013) PLoS One , vol.8 , pp. e81566
    • Shi, L.1    Liu, L.2    He, T.3    Guo, X.4    Yu, Z.5    Yin, S.6    Wang, J.7
  • 49
    • 0020317096 scopus 로고
    • Ribbon synapses in the developing intact and cultured organ of corti in the mouse
    • Sobkowicz H.M., Rose J.E., Scott G.E., Slapnick S.M. Ribbon synapses in the developing intact and cultured organ of corti in the mouse. J Neurosci 1982, 2:942-957.
    • (1982) J Neurosci , vol.2 , pp. 942-957
    • Sobkowicz, H.M.1    Rose, J.E.2    Scott, G.E.3    Slapnick, S.M.4
  • 50
    • 0023025610 scopus 로고
    • Distribution of synaptic ribbons in the developing organ of corti
    • Sobkowicz H.M., Rose J.E., Scott G.L., Levenick C.V. Distribution of synaptic ribbons in the developing organ of corti. J Neurocytol 1986, 15:693-714.
    • (1986) J Neurocytol , vol.15 , pp. 693-714
    • Sobkowicz, H.M.1    Rose, J.E.2    Scott, G.L.3    Levenick, C.V.4
  • 52
    • 11144256172 scopus 로고    scopus 로고
    • Structure and function of ribbon synapses
    • Sterling P., Matthews G. Structure and function of ribbon synapses. Trends Neurosci 2005, 28:20-29.
    • (2005) Trends Neurosci , vol.28 , pp. 20-29
    • Sterling, P.1    Matthews, G.2
  • 53
    • 84925813088 scopus 로고    scopus 로고
    • Noise-induced hearing loss: an occupational medicine perspective
    • Stucken E.Z., Hong R.S. Noise-induced hearing loss: an occupational medicine perspective. Curr Opin Otolaryngol Head Neck Surg 2014, 22:388-393.
    • (2014) Curr Opin Otolaryngol Head Neck Surg , vol.22 , pp. 388-393
    • Stucken, E.Z.1    Hong, R.S.2
  • 56
    • 77549083577 scopus 로고    scopus 로고
    • Calcium, ischemia and excitotoxicity
    • Szydlowska K., Tymianski M. Calcium, ischemia and excitotoxicity. Cell Calcium 2010, 47:122-129.
    • (2010) Cell Calcium , vol.47 , pp. 122-129
    • Szydlowska, K.1    Tymianski, M.2
  • 57
    • 77956850256 scopus 로고    scopus 로고
    • Molecular anatomy of the hair cell's ribbon synapse
    • Uthaiah R.C., Hudspeth A.J. Molecular anatomy of the hair cell's ribbon synapse. J Neurosci 2010, 30:12387-12399.
    • (2010) J Neurosci , vol.30 , pp. 12387-12399
    • Uthaiah, R.C.1    Hudspeth, A.J.2
  • 58
    • 0037294080 scopus 로고    scopus 로고
    • The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina
    • von Kriegstein K., Schmitz F. The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina. Cell Tissue Res 2003, 311:159-173.
    • (2003) Cell Tissue Res , vol.311 , pp. 159-173
    • von Kriegstein, K.1    Schmitz, F.2
  • 59
    • 84875373581 scopus 로고    scopus 로고
    • Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration
    • Walters B.J., Zuo J. Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration. Hear Res 2013, 297:68-83.
    • (2013) Hear Res , vol.297 , pp. 68-83
    • Walters, B.J.1    Zuo, J.2
  • 61
    • 34548392824 scopus 로고    scopus 로고
    • Conductive hearing loss disrupts synaptic and spike adaptation in developing auditory cortex
    • Xu H., Kotak V.C., Sanes D.H. Conductive hearing loss disrupts synaptic and spike adaptation in developing auditory cortex. J Neurosci 2007, 27:9417-9426.
    • (2007) J Neurosci , vol.27 , pp. 9417-9426
    • Xu, H.1    Kotak, V.C.2    Sanes, D.H.3
  • 63
    • 80052621140 scopus 로고    scopus 로고
    • Calcium and cell death mechanisms: a perspective from the cell death community
    • Zhivotovsky B., Orrenius S. Calcium and cell death mechanisms: a perspective from the cell death community. Cell Calcium 2011, 50:211-221.
    • (2011) Cell Calcium , vol.50 , pp. 211-221
    • Zhivotovsky, B.1    Orrenius, S.2
  • 64
    • 79952409731 scopus 로고    scopus 로고
    • Calcium dysregulation and homeostasis of neural calcium in the molecular mechanisms of neurodegenerative diseases provide multiple targets for neuroprotection
    • Zundorf G., Reiser G. Calcium dysregulation and homeostasis of neural calcium in the molecular mechanisms of neurodegenerative diseases provide multiple targets for neuroprotection. Antioxid Redox Signal 2011, 14:1275-1288.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1275-1288
    • Zundorf, G.1    Reiser, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.