The Effects of Arterial Hypertension and Age on the Sublingual Microcirculation of Healthy Volunteers and Outpatients with Cardiovascular Risk Factors

Microcirculation

Volumn 22, Issue 6, 2015, Pages 485-492

  Kanoore Edul, Vanina S ^a,b,c   Ince, Can ^c   Estenssoro, Elisa ^d   Ferrara, Gonzalo ^a,d   Arzani, Yanina ^e   Salvatori, Carolina ^f   Dubin, Arnaldo ^a,f  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^b HOSPITAL JUAN A FERNÁNDEZ   (Argentina)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d HOSPITAL SAN MARTÍN   (Argentina)

^e Miembro del Consejo de Cardiometabolismo de la Sociedad Argentina de Cardiología   (Argentina)

^f Sanatorio Otamendi y Miroli   (Argentina)

Author keywords

Age; Chronic arterial hypertension; Exercise; Sublingual microcirculation

Indexed keywords

ADULT; AGE; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEMODYNAMIC PARAMETERS; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; MICROVASCULAR FLOW INDEX; PERFUSED VASCULAR DENSITY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RED BLOOD CELL VELOCITY; SMOKING; SUBLINGUAL MICROCIRCULATION; TOTAL VASCULAR DENSITY; CHRONIC DISEASE; CLINICAL TRIAL; CROSS-SECTIONAL STUDY; MIDDLE AGED; MOUTH FLOOR; MULTICENTER STUDY; OUTPATIENT; PATHOLOGY; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; RISK FACTOR; VASCULARIZATION;

ADULT; AGE FACTORS; AGED; CHRONIC DISEASE; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; HYPERTENSION; MALE; MICROCIRCULATION; MIDDLE AGED; MOUTH FLOOR; OUTPATIENTS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84938868978     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1111/micc.12219     Document Type: Article

References (45)

1. Abdo IS, Turek Z, Parizkova R, Cerny V. Imaging of the sublingual microcirculation in elderly patients-a pilot study. Appl Cardiopulm Pathophysiol 16: 276-282, 2012.
2. Antonios TF, Raghuraman RP, D'Souza R, Nathan P, Wang D, Manyonda IT. Capillary remodeling in infants born to hypertensive pregnancy: pilot study. Am J Hypertens 25: 848-853, 2012.
3. Antonios TF, Rattray FM, Singer DR, Markandu ND, Mortimer PS, MacGregor GA. Rarefaction of skin capillaries in normotensive offspring of individuals with essential hypertension. Heart 89: 175-178, 2003.
4. Antonios TF, Singer DR, Markandu ND, Mortimer PS, MacGregor GA. Structural skin capillary rarefaction in essential hypertension. Hypertension 33: 998-1001, 1999.
5. Bearden SE, Payne GW, Chisty A, Segal SS. Arteriolar network architecture and vasomotor function with ageing in mouse gluteus maximus muscle. J Physiol 561(Pt 2): 535-545, 2004.
6. Black MA, Green DJ, Cable NT. Exercise prevents age-related decline in nitric-oxide-mediated vasodilator function in cutaneous microvessels. J Physiol 586: 3511-3524, 2008.
7. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 289: 2560-2572, 2003.
8. Cocks M, Shaw CS, Shepherd SO, Fisher JP, Ranasinghe AM, Barker TA, Tipton KD, Wagenmakers AJ. Sprint interval and endurance training are equally effective in increasing muscle microvascular density and eNOS content in sedentary males. J Physiol 591: 641-656, 2013.
9. Davidson YS, Clague JE, Horan MA, Pendleton N. The effect of aging on skeletal muscle capillarization in a murine model. J Gerontol A Biol Sci Med Sci 54: B448-B451, 1999.
10. De Backer D, Creteur J, Dubois MJ, Sakr Y, Koch M, Verdant C, Vincent JL. The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects. Crit Care Med 34: 403-408, 2006.
11. De Backer D, Creteur J, Preiser JC, Dubois MJ, Vincent JL. Microvascular blood flow is altered in patients with sepsis. Am J Respir Crit Care Med 166: 98-104, 2002.
12. De Backer D, Donadello K, Sakr Y, Ospina-Tascon G, Salgado D, Scolletta S, Vincent JL. Microcirculatory alterations in patients with severe sepsis: impact of time of assessment and relationship with outcome. Crit Care Med 41: 791-799, 2013.
13. De Ciuceis C, Salvetti M, Rossini C, Muiesan ML, Paini A, Duse S, La Boria E, Semeraro F, Cancarini A, Rosei CA, Sarkar A, Ruggeri G, Caimi L, Ricotta D, Rizzoni D, Rosei EA. Effect of antihypertensive treatment on microvascular structure, central blood pressure and oxidative stress in patients with mild essential hypertension. J Hypertens 32: 565-574, 2014.
14. Debbabi H, Bonnin P, Levy BI. Effects of blood pressure control with perindopril/indapamide on the microcirculation in hypertensive patients. Am J Hypertens 23: 1136-1143, 2010.
15. Degens H, Veerkamp JH, van Moerkerk HTB, Turek Z, Hoofd LJC, Binkhorst RA. Metabolic capacity, fibre type area and capillarization of rat plantaris muscle. Effects of age, overload and training and relationship with fatigue resistance. Int J Biochem 25: 1141-1148, 1993.
16. Dobbe JG, Streekstra GJ, Atasever B, van Zijderveld R, Ince C. Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis. Med Biol Eng Comput 46: 659-670, 2008.
17. Dubin A, Pozo MO, Casabella CA, Pálizas F Jr, Murias G, Moseinco MC, Kanoore Edul VS, Pálizas F, Estenssoro E, Ince C. Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study. Crit Care 13: R92, 2009.
18. Eckel RH, Jakicic JM, Ard JD, de Jesus JM, Houston Miller N, Hubbard VS, Lee IM, Lichtenstein AH, Loria CM, Millen BE, Nonas CA, Sacks FM, Smith SC Jr, Svetkey LP, Wadden TA, Yanovski SZ, Kendall KA, Morgan LC, Trisolini MG, Velasco G, Wnek J, Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, DeMets D, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen WK, Smith SC Jr, Tomaselli GF; American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129(25 Suppl. 2): S76-S99, 2014.
19. Edul VS, Enrico C, Laviolle B, Vazquez AR, Ince C, Dubin A. Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock. Crit Care Med 40: 1443-1448, 2012.
20. Goedhart PT, Khalilzada M, Bezemer R, Merza J, Ince C. Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation. Opt Express 15: 15101-15114, 2007.
21. Haack DW, Schaffer JJ, Simpson JG. Comparisons of cutaneous microvessels from spontaneously hypertensive, normotensive Wistar-Kyoto, and normal Wistar rats. Proc Soc Exp Biol Med 164: 453-458, 1980.
22. Henrich H, Hertel R, Assmann R. Structural differences in the mesentery microcirculation between normotensive and spontaneously hypertensive rats. Pflugers Arch 375: 153-159, 1978.
23. Hernandez G, Boerma EC, Dubin A, Bruhn A, Koopmans M, Edul VK, Ruiz C, Castro R, Pozo MO, Pedreros C, Veas E, Fuentealba A, Kattan E, Rovegno M, Ince C. Severe abnormalities in microvascular perfused vessel density are associated to organ dysfunctions and mortality and can be predicted by hyperlactatemia and norepinephrine requirements in septic shock patients. J Crit Care 28: 538.e9-538.e14, 2013.
24. Huang CX, Qiu X, Wang S, Wu H, Xia L, Li C, Gao Y, Zhang L, Xiu Y, Chao F, Tang Y. Exercise-induced changes of the capillaries in the cortex of middle-aged rats. Neuroscience 233: 139-145, 2013.
25. Hutchins PM, Lynch CD, Cooney PT, Curseen KA. The microcirculation in experimental hypertension and aging. Cardiovasc Res 32: 772-780, 1996.
26. Ito Y, Sørensen KK, Bethea NW, Svistounov D, McCuskey MK, Smedsrød BH, McCuskey RS. Age-related changes in the hepatic microcirculation in mice. Exp Gerontol 42: 789-797, 2007.
27. James MA, Tullett J, Hemsley AG, Shore AC. Effects of aging and hypertension on the microcirculation. Hypertension 47: 968-974, 2006.
28. Jung F, Kolepke W, Spitzer S, Kiesewetter H, Ruprecht KW, Bach R, Schieffer H, Wenzel E. Primary and secondary microcirculatory disorders in essential hypertension. Clin Investig 71: 132-138, 1993.
29. Jung F, Pindur G, Ohlmann P, Spitzer G, Sternitzky R, Franke RP, Leithäuser B, Wolf S, Park JW. Microcirculation in hypertensive patients. Biorheology 50: 241-255, 2013.
30. Jung F, Spitzer S, Kiesewetter H, Feldmann M, Kotitschke G, Blum C, Wenzel E, Jutzler GA. Comparative investigation of the microcirculation in patients with hypertension and healthy adults. Klin Wochenschr 64: 956-961, 1986.
31. Khalil A, Humeau-Heurtier A, Mahé G, Abraham P. Laser speckle contrast imaging: age-related changes in microvascular blood flow and correlation with pulse-wave velocity in healthy subjects. J Biomed Opt 20: 051010, 2015.
32. Landau J, Davis E. Capillary thinning and high capillary blood-pressure in hypertension. Lancet 269: 1327-1330, 1957.
33. Li L, Mac-Mary S, Sainthillier JM, Nouveau S, de Lacharriere O, Humbert P. Age-related changes of the cutaneous microcirculation in vivo. Gerontology 52: 142-153, 2006.
34. Pozo MO, Kanoore Edul VS, Ince C, Dubin A. Comparison of different methods for the calculation of the microvascular flow index. Crit Care Res Pract 2012: 102483, 2012.
35. Pranskunas A, Koopmans M, Koetsier PM, Pilvinis V, Boerma EC. Microcirculatory blood flow as a tool to select ICU patients eligible for fluid therapy. Intensive Care Med 39: 612-619, 2013.
36. Prewitt RL, Chen II, Dowell R. Development of microvascular rarefaction in the spontaneously hypertensive rat. Am J Physiol 243: H243-H251, 1982.
37. Reynolds T, Vivian-Smith A, Jhanji S, Pearse RM. Observational study of the effects of age, diabetes mellitus, cirrhosis and chronic kidney disease on sublingual microvascular flow. Perioper Med (Lond) 2: 7, 2013.
38. Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32: 1825-1831, 2004.
39. Scardina GA, Cacioppo A, Messina P. Anatomical evaluation of oral microcirculation: capillary characteristics associated with sex or age group. Ann Anat 191: 371-378, 2009.
40. Seidman MD, Khan MJ, Dolan DF, Quirk WS. Age-related differences in cochlear microcirculation and auditory brain stem response. Arch Otolaryngol Head Neck Surg 122: 1221-1226, 1996.
41. Sullivan JM, Prewitt RL, Josephs JA. Attenuation of the microcirculation in young patients with high-output borderline hypertension. Hypertension 5: 844-851, 1983.
42. Tew GA, Klonizakis M, Saxton JM. Effects of ageing and fitness on skin-microvessel vasodilator function in humans. Eur J Appl Physiol 109: 173-181, 2010.
43. Unthank JL, Lash JM, Bohlen HG. Maturation of the rat intestinal microvasculature from juvenile to early adult life. Am J Physiol 259: G282-G289, 1990.
44. Wolf S, Arend O, Schulte K, Ittel TH, Reim M. Quantification of retinal capillary density and flow velocity in patients with essential hypertension. Hypertension 23: 464-467, 1994.
45. Yamamoto Y, Yamamoto Y, Marugame A, Ogura M, Saito A, Ohta K, Fukumoto M, Murata T. Age-related decrease of the retinal vasculature area identified with a novel computer-aided analysis system. Tohoku J Exp Med 228: 229-237, 2012.