Rutaecarpine and evodiamine selected as β1-AR inhibitor candidates using β1-AR/CMC-offline-UPLC/MS prevent cardiac ischemia-reperfusion injury via energy modulation

Journal of Pharmaceutical and Biomedical Analysis

Volumn 115, Issue , 2015, Pages 307-314

  Xue, Hui ^a   Cheng, Yongjie ^b   Wang, Xin ^a   Yue, Yuan ^c   Zhang, Weifang ^a   Li, Xiaoni ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b Shanxi Education College   (China)

^c TSINGHUA UNIVERSITY   (China)

Author keywords

Cell membrane chromatography; Energy metabolism; Evodiamine; Ischemia reperfusion; Rutaecarpine; 1 Adrenergic receptor

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATE; BETA 1 ADRENERGIC RECEPTOR; CYCLIC AMP; EVODIAMINE; FATTY ACID; GLUCOSE; LACTATE DEHYDROGENASE; LACTIC ACID; METOPROLOL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLANT EXTRACT; RUTAECARPINE; TETRADIUM RUTICARPUM EXTRACT; UNCLASSIFIED DRUG; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; INDOLE ALKALOID; QUINAZOLINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG IDENTIFICATION; DRUG SCREENING; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; METABOLIC DISORDER; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TETRADIUM RUTICARPUM; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; CELL SURVIVAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; EVODIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PROCEDURES; WISTAR RAT;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; CELL MEMBRANE; CELL SURVIVAL; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETULUS; ENERGY METABOLISM; EVODIA; INDOLE ALKALOIDS; MALE; MASS SPECTROMETRY; MYOCARDIAL REPERFUSION INJURY; QUINAZOLINES; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-1;

EID: 84938828500     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.07.022     Document Type: Article

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