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Volumn 3, Issue 12, 2014, Pages 1-3

Reversal of natural killer cell exhaustion by TIM-3 blockade

Author keywords

exhaustion; immune checkpoint; melanoma; natural killer cells; Tim 3

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; ECALECTIN; EOMESODERMIN; GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; MEMBRANE PROTEIN; NATURAL KILLER CELL RECEPTOR NKG2D; PROGRAMMED DEATH 1 RECEPTOR; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING MOLECULE 3; UNCLASSIFIED DRUG;

EID: 84938799943     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/21624011.2014.946365     Document Type: Article
Times cited : (80)

References (10)
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    • J.Fourcade, Z.Sun, M.Benallaoua, P.Guillaume, I.F.Luescher, C.Sander, J.M.Kirkwood, V.Kuchroo, H.M.Zarour. Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J Exp Med 2010; 207:2175-86; PMID:20819923; http://dx.doi.org/10.1084/jem.20100637
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    • Fourcade, J.1    Sun, Z.2    Benallaoua, M.3    Guillaume, P.4    Luescher, I.F.5    Sander, C.6    Kirkwood, J.M.7    Kuchroo, V.8    Zarour, H.M.9
  • 4
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    • Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
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    • K.Sakuishi, L.Apetoh, J.M.Sullivan, B.R.Blazar, V.K.Kuchroo, A.C.Anderson. Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 2010; 207:2187-94; PMID:20819927; http://dx.doi.org/10.1084/jem.20100643
    • (2010) J Exp Med , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.M.3    Blazar, B.R.4    Kuchroo, V.K.5    Anderson, A.C.6
  • 5
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    • Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells
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    • S.Gill, A.E.Vasey, A.De Souza, J.Baker, A.T.Smith, H.E.Kohrt, M.Florek, K.D.GibbsJr, K.Tate, D.S.Ritchie, Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells. Blood 2012; 119:5758-68; PMID:22544698; http://dx.doi.org/10.1182/blood-2012-03-415364
    • (2012) Blood , vol.119 , pp. 5758-5768
    • Gill, S.1    Vasey, A.E.2    De Souza, A.3    Baker, J.4    Smith, A.T.5    Kohrt, H.E.6    Florek, M.7    Gibbs, K.D.8    Tate, K.9    Ritchie, D.S.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.