Targeting ceramide metabolic pathway induces apoptosis in human breast cancer cell lines

Biochemical and Biophysical Research Communications

Volumn 464, Issue 3, 2015, Pages 833-839

  Vethakanraj, Helen Shiphrah ^a   Babu, Thabraz Ahmed ^a   Sudarsanan, Ganesh Babu ^a   Duraisamy, Prabhu Kumar ^a   Ashok Kumar, Sekar ^a  

^a ANNA UNIVERSITY   (India)

Author keywords

Acid ceramidase; Apoptosis; Breast cancer cell lines; Ceranib 2

Indexed keywords

ACID CERAMIDASE; CERANIB 2; ESTROGEN RECEPTOR; HYDROLASE INHIBITOR; LIPOCORTIN 5; PROTEIN BAD; PROTEIN BAX; PROTEIN BID; TAMOXIFEN; UNCLASSIFIED DRUG; 3-(3-(4-METHOXYPHENYL)ACRYLOYL)-4-PHENYL-1H-QUINOLIN-2-ONE; ANTINEOPLASTIC AGENT; ASAH1 PROTEIN, HUMAN; CERAMIDE; ENZYME INHIBITOR; QUINOLONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE G1 PHASE; CELL CYCLE PHASE; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME METABOLISM; GEL ELECTROPHORESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IC50; MCF 7 CELL LINE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; CELL CYCLE; CELL SURVIVAL; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY;

ACID CERAMIDASE; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL SURVIVAL; CERAMIDES; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; MCF-7 CELLS; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR TARGETED THERAPY; QUINOLONES; TAMOXIFEN;

EID: 84938749023     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.07.047     Document Type: Article

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