The RNA-binding protein PCBP2 inhibits Ang II-induced hypertrophy of cardiomyocytes though promoting GPR56 mRNA degeneration

Biochemical and Biophysical Research Communications

Volumn 464, Issue 3, 2015, Pages 679-684

  Zhang, Yunjiao ^a   Si, Yi ^a   Ma, Nan ^a   Mei, Ju ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Angiotensin II; Cardiomyocyte hypertrophy; GRP56; PCBP2

Indexed keywords

ANGIOTENSIN II; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 56; MESSENGER RNA; POLY(C) BINDING PROTEIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; GPR56 PROTEIN, HUMAN; GPR56 PROTEIN, MOUSE; GPR56 PROTEIN, RAT; PCBP2 PROTEIN, HUMAN; PCBP2 PROTEIN, MOUSE; POLY(RC) BINDING PROTEIN 2, RAT;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ENZYME INHIBITION; GENE OVEREXPRESSION; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECEPTOR DOWN REGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CARDIOMEGALY; CELL CULTURE; CELL ENLARGEMENT; CELL LINE; CYTOLOGY; DOWN REGULATION; GENE SILENCING; GENETICS; MALE; METABOLISM; PATHOLOGY; RAT; RNA STABILITY;

ANGIOTENSIN II; ANIMALS; CARDIOMEGALY; CELL ENLARGEMENT; CELL LINE; CELLS, CULTURED; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; RATS; RECEPTORS, G-PROTEIN-COUPLED; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 84938747739     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.06.139     Document Type: Article

References (32)

1. B.J. Maron, and M.S. Maron Hypertrophic cardiomyopathy Lancet 381 2013 242 255
2. J. Heineke, and J.D. Molkentin Regulation of cardiac hypertrophy by intracellular signalling pathways Nat. Rev. Mol. Cell. Biol. 7 2006 589 600
3. J.A. Hill, and E.N. Olson Cardiac Plasticity N. Engl. J. Med. 358 2008 1370 1380
4. R.E. Hershberger, D.J. Hedges, and A. Morales Dilated cardiomyopathy: the complexity of a diverse genetic architecture Nat. Rev. Cardiol. 10 2013 531 547
5. A.V. Makeyev, and S.A. Liebhaber The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms Rna 8 2002 265 278
6. P. Sean, J.H. Nguyen, and B.L. Semler The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation Virology 378 2008 243 253
7. P. Sean, J.H. Nguyen, and B.L. Semler Altered interactions between stem-loop IV within the 5' noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: effects on IRES-mediated translation and viral infectivity Virology 389 2009 45 58
8. W. Han, Z. Xin, Z. Zhao, W. Bao, X. Lin, B. Yin, J. Zhao, J. Yuan, B. Qiang, and X. Peng RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3 J. Clin. Investigation 123 2013 2103 2118
9. R.J. Molinaro, B.K. Jha, K. Malathi, S. Varambally, A.M. Chinnaiyan, and R.H. Silverman Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells Nucleic Acids Res. 34 2006 6684 6695
10. J.S. Chang, R. Santhanam, R. Trotta, P. Neviani, A.M. Eiring, E. Briercheck, M. Ronchetti, D.C. Roy, B. Calabretta, M.A. Caligiuri, and D. Perrotti High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation Blood 110 2007 994 1003
11. S.Y. Chan, A.K. Chan, B.P. Cheung, Y. Liang, and M.P. Leung Identification of genes expressed during myocardial development Chin. Med. J. Engl. 116 2003 1329 1332
12. S. Shashidhar, G. Lorente, U. Nagavarapu, A. Nelson, J. Kuo, J. Cummins, K. Nikolich, R. Urfer, and E.D. Foehr GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion Oncogene 24 2005 1673 1682
13. L. Xu, S. Begum, J.D. Hearn, and R.O. Hynes GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis Proc. Natl. Acad. Sci. U. S. A. 103 2006 9023 9028
14. L. Yang, S. Friedland, N. Corson, and L. Xu GPR56 inhibits melanoma growth by internalizing and degrading Its Ligand TG2 Cancer Res. 74 2014 1022 1031
15. S. Koirala, Z. Jin, X. Piao, and G. Corfas GPR56-regulated granule cell adhesion is essential for rostral cerebellar development J. Neurosci. 29 2009 7439 7449
16. S. Giera, Y. Deng, R. Luo, S.D. Ackerman, A. Mogha, K.R. Monk, Y. Ying, S.-J. Jeong, M. Makinodan, A.R. Bialas, B.S. Chang, B. Stevens, G. Corfas, and X. Piao The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development Nat. Commun. 6 2015
17. B.-I. Bae, I. Tietjen, K.D. Atabay, G.D. Evrony, M.B. Johnson, E. Asare, P.P. Wang, A.Y. Murayama, K. Im, S.N. Lisgo, L. Overman, N. Šestan, B.S. Chang, A.J. Barkovich, P.E. Grant, M. Topçu, J. Politsky, H. Okano, X. Piao, and C.A. Walsh Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning Science 343 2014 764 768
18. S.D. Ackerman, C. Garcia, X. Piao, D.H. Gutmann, and K.R. Monk The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA Nat. Commun. 6 2015
19. M.P. Wu, J.R. Doyle, B. Barry, A. Beauvais, A. Rozkalne, X. Piao, M.W. Lawlor, A.S. Kopin, C.A. Walsh, and E. Gussoni G-protein coupled receptor 56 promotes myoblast fusion through serum response factor- and nuclear factor of activated T-cell-mediated signalling but is not essential for muscle development in vivo Febs J. 280 2013 6097 6113
20. J.P. White, C.D. Wrann, R.R. Rao, S.K. Nair, M.P. Jedrychowski, J.S. You, V. Martinez-Redondo, S.P. Gygi, J.L. Ruas, T.A. Hornberger, Z. Wu, D.J. Glass, X. Piao, and B.M. Spiegelman G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy Proc. Natl. Acad. Sci. U. S. A. 111 2014 15756 15761
21. N.R. Sundaresan, P. Vasudevan, L. Zhong, G. Kim, S. Samant, V. Parekh, V.B. Pillai, P.V. Ravindra, M. Gupta, V. Jeevanandam, J.M. Cunningham, C.X. Deng, D.B. Lombard, R. Mostoslavsky, and M.P. Gupta The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun Nat. Med. 18 2012 1643 1650
22. J.B. Regard, I.T. Sato, and S.R. Coughlin Anatomical profiling of G protein-coupled receptor expression Cell 135 2008 561 571
23. J.O. Mudd, and D.A. Kass Tackling heart failure in the twenty-first century Nature 451 2008 919 928
24. B. Stefanovic, C. Hellerbrand, M. Holcik, M. Briendl, S. Aliebhaber, and D.A. Brenner Posttranscriptional regulation of collagen alpha1(I) mRNA in hepatic stellate cells Mol. Cell. Biol. 17 1997 5201 5209
25. W.R. Paulding, and M.F. Czyzyk-Krzeska Regulation of tyrosine hydroxylase mRNA stability by protein-binding, pyrimidine-rich sequence in the 3'-untranslated region J. Biol. Chem. 274 1999 2532 2538
26. E. Rieder, W. Xiang, A. Paul, and E. Wimmer Analysis of the cloverleaf element in a human rhinovirus type 14/poliovirus chimera: correlation of subdomain D structure, ternary protein complex formation and virus replication J. Gen. Virol. 84 2003 2203 2216
27. S. Fukushi, M. Okada, T. Kageyama, F.B. Hoshino, K. Nagai, and K. Katayama Interaction of poly(rC)-binding protein 2 with the 5'-terminal stem loop of the hepatitis C-virus genome Virus Res. 73 2001 67 79
28. P. Tingting, F. Caiyun, Y. Zhigang, Y. Pengyuan, and Y. Zhenghong Subproteomic analysis of the cellular proteins associated with the 3' untranslated region of the hepatitis C virus genome in human liver cells Biochem. Biophys. Res. Commun. 347 2006 683 691
29. F. You, H. Sun, X. Zhou, W. Sun, S. Liang, Z. Zhai, and Z. Jiang PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4 Nat. Immunol. 10 2009 1300 1308
30. W. Han, Z. Xin, Z. Zhao, W. Bao, X. Lin, B. Yin, J. Zhao, J. Yuan, B. Qiang, and X. Peng RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3 J. Clin. Invest 123 2013 2103 2118
31. M. Nishida, Y. Sato, A. Uemura, Y. Narita, H. Tozaki-Saitoh, M. Nakaya, T. Ide, K. Suzuki, K. Inoue, T. Nagao, and H. Kurose P2Y6 receptor-Gα12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis EMBO J. 27 2008 3104 3115
32. Y. Maruyama, M. Nishida, Y. Sugimoto, S. Tanabe, J.H. Turner, T. Kozasa, T. Wada, T. Nagao, and H. Kurose Gα12/13 mediates α1-Adrenergic receptor-induced cardiac hypertrophy Circulation Res. 91 2002 961 969