Metformin for the management of gestational diabetes mellitus

Australian and New Zealand Journal of Obstetrics and Gynaecology

Volumn 55, Issue 4, 2015, Pages 303-308

  Singh, Kamal P ^a   Rahimpanah, Farhad ^b   Barclay, Margot ^b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b LIVERPOOL HOSPITAL   (Australia)

Author keywords

gestational diabetes mellitus; literature review; metformin; pregnancy

Indexed keywords

INSULIN; METFORMIN; ANTIDIABETIC AGENT;

FEMALE; FETUS OUTCOME; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INSULIN TREATMENT; PREGNANCY DIABETES MELLITUS; PREGNANCY OUTCOME; PREMATURE LABOR; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; TREATMENT OUTCOME; WEIGHT GAIN; DIABETES, GESTATIONAL; PREGNANCY;

DIABETES, GESTATIONAL; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; METFORMIN; PREGNANCY; PREGNANCY OUTCOME;

EID: 84938738282     PISSN: 00048666     EISSN: 1479828X     Source Type: Journal    
DOI: 10.1111/ajo.12311     Document Type: Review

References (27)

1. American Diabetes Association. Standards of care in diabetes-gestational diabetes. Diabetes Care 2013; 36 (Suppl 1): S11-S66.
2. Diabetes Australia. Gestational Diabetes; Canberra, 2014. [Accessed 27 May 2014.] Available from: http://www.diabetesaustralia.com.au/Living-with-Diabetes/Gestational-Diabetes/.
3. Langer O, Yogev Y, Most O, Xenakis EM,. Gestational diabetes: the consequences of not treating. Am J Obstet Gynecol 2005; 192: 989-997.
4. Falavigna M, Schmidt MI, Trujillo J, et al,. Effectiveness of gestational diabetes treatment: a systematic review with quality of evidence assessment. Diabetes Res Clin Pract 2012; 98 (3): 396-405.
5. Norman RJ, Wang JX, Hague W,. Should we continue or stop insulin sensitizing drugs during pregnancy? Curr Opin Obstet Gynecol 2004; 16 (3): 245-250.
6. Hellmuth E, Damm P, Molsted-Pedersen L,. Oral hypoglycaemic agents in 118 diabetic pregnancies. Diabet Med 2000; 17: 507-511.
7. Gutzin SJ, Kozer E, Magee LA, et al,. The safety of oral hypoglycemic agents in the first trimester of pregnancy: a meta-analysis. Can J Clin Pharmacol 2003; 10: 179-183.
8. Graham GG, Punt J, Arora M, et al,. Clinical pharmacokinetics of metformin. Clin Pharmacokinet 2011; 50 (2): 81-98.
9. Lautatzis ME, Goulis DG, Vrontakis M,. Efficacy and safety of metformin during pregnancy in women with gestational diabetes mellitus or polycystic ovary syndreom: a systematic review. Metabolism 2013; 62: 1522-1534.
10. Hughes RC, Gardiner SJ, Begg EJ, Zhang M,. Effect of pregnancy on the pharmacokinetics of metformin. Diabet Med 2006; 23L: 323-326.
11. AMH. Australian Medicines Handbook. Adelaide: Australian Medicines Handbooks Pty Ltd, 2014. [Accessed 12 April 2014.] Available from: http://www.amh.net.au.
12. eTG-complete. Gestational Diabetes Melbourne: Therapeuutic Guidlines Limited, 2014. [Accessed 27 May 2014.] Available from: http://www.tg.org.au/?sectionid=71.
13. Jadad AR, Moore RA, Carroll D, et al,. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17 (1): 1-12.
14. Spaulonci CP, Bernardes LS, Trindade TC, et al,. Randomized trial of metformin vs insulin in the management of gestational diabetes. Am J Obstet Gynecol 2013; 209: 34e1-34e7.
15. Niromanesh S, Alavi A, Sharbaf FR, et al,. Metformin compared with insulin in the management of gestational diabetes mellitus: a randomized clinical trial. Diabetes Res Clin Pract 2012; 98 (3): 422-429.
16. Rowan JA, Hague WM, Gao W, et al,. Metformin versus insulin for the treatment of gestational diabetes. N Engl J Med 2008; 358: 2003-2015.
17. Hassan JA, Karim N, Sheikh Z,. Metformin prevents macrosomia and neonatal morbidity in gestational diabetes. Pak J Med Sci 2012; 28 (3): 384-389.
18. Ijas H, Vaarasmaki M, Morin-Papunen L, et al,. Metformin should be considered in the treatment of gestational diabetes: a prospective randomised study. BJOG 2011; 118: 880-885.
19. Johnson JW, Longmate JA, Frentzen B,. Excessive maternal weight and pregnancy outcome. Am J Obstet Gynecol 1992; 167: 353-370 discussion 70-2.
20. Cornblath M, Ichord R,. Hypoglycemia in the neonate. Semin Perinatol 2000; 24: 136-149.
21. Moore LE, Briery CM, Clokey D, et al,. Metformin and insulin in the management of gestational diabetes mellitus: preliminary results of a comparison. J Reprod Med 2007; 52: 1011-1015.
22. Tertti K, Ekblad U, Koskinen P, et al,. Metformin vs. insulin in gestational diabetes. A randomized study characterizing metformin patients needing additional insulin. Diabetes Obes Metab 2013; 15 (3): 246-251.
23. Coustan DR, Carpenter MW,. The diagnosis of gestational diabetes. Diabetes Care 1998; 21 (Suppl 2): B5-B8.
24. Rowan JA, Rush EC, Obolonkin V, et al,. Metformin in Gestational Diabetes: The Offspring Follow-Up (MiG TOFU): body composition at 2 years of age. Diabetes Care 2011; 34: 2279-2284.
25. Coetzee EJ, Jackson WP,. The management of non-insulin-dependent diabetes during pregnancy. Diabetes Res Clin Pract 1985; 1: 281-287.
26. Gilbert C, Valois M, Koren G,. Pregnancy outcome after first-trimester exposure to metformin: a meta-analysis. Fertil Steril 2006; 86: 658-663.
27. Glueck CJ, Bornovali S, Pranikoff J, et al,. Metformin, pre-eclampsia, and pregnancy outcomes in women with polycystic ovary syndrome. Diabet Med 2004; 21 (8): 829-836.