Stimulation of the cardiac myocyte Na+-K+ pump due to reversal of its constitutive oxidative inhibition

American Journal of Physiology - Cell Physiology

Volumn 309, Issue 4, 2015, Pages C239-C250

  Chia, Karin K M ^a,b   Liu, Chia Chi ^a   Hamilton, Elisha J ^a   Garcia, Alvaro ^a   Fry, Natasha A ^a   Hannam, William ^a   Figtree, Gemma A ^a,c   Rasmussen, Helge H ^a,c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Glutathionylation; Nitric oxide; Oxidative stress; Sodium potassium (Na+ k+) ATPase; Soluble guanylyl cyclase

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) BETA1 SUBUNIT; ANGIOTENSIN II; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GUANYLATE CYCLASE; HYDROETHIDINE; LIFICIGUAT; NITRIC OXIDE; OXYGEN; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE P22 PHOX SUBUNIT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE P47 PHOX SUBUNIT; UNCLASSIFIED DRUG; ENZYME INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE 2;

ANIMAL CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME MODIFICATION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; FLUORESCENCE; GLUTATHIONYLATION; HEART MUSCLE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; RABBIT;

ANIMALS; CELLS, CULTURED; ENZYME INHIBITORS; MYOCYTES, CARDIAC; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN PHOSPHATASE 2; RABBITS; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84938725202     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00392.2014     Document Type: Article

References (45)

1. Bean BP. Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology. J Gen Physiol 86: 1–30, 1985.
2. + pump mediated by glutathionylation of its β 1 subunit. J Biol Chem 286: 18562–18572, 2011.
3. Bollen M, Peti W, Ragusa MJ, Beullens M. The extended PP1 toolkit: designed to create specificity. Trends Biochem Sci 35: 450–458, 2010.
4. +. Am J Physiol Cell Physiol 277: C461–C468, 1999.
5. + pump by reversal of an inhibitory oxidative modification. Circulation 122: 2699–2708, 2010.
6. Chatfield K, Eastman A. Inhibitors of protein phosphatases 1 and 2A differentially prevent intrinsic and extrinsic apoptosis pathways. Biochem Biophys Res Commun 323: 1313–1320, 2004.
7. Curnutte JT, Erickson RW, Ding J, Badwey JA. Reciprocal interactions between protein kinase C and components of the NADPH oxidase complex may regulate superoxide production by neutrophils stimulated with a phorbol ester. J Biol Chem 269: 10813–10819, 1994.
8. Dawson-Scully K, Armstrong GA, Kent C, Robertson RM, Sokolowski MB. Natural variation in the thermotolerance of neural function and behavior due to a cGMP-dependent protein kinase. PLoS One 2: e773, 2007.
9. Dawson-Scully K, Bukvic D, Chakaborty-Chatterjee M, Ferreira R, Milton SL, Sokolowski MB. Controlling anoxic tolerance in adult Drosophila via the cGMP-PKG pathway. J Exp Biol 213: 2410–2416, 2010.
10. Fernandez JJ, Candenas ML, Souto ML, Trujillo MM, Norte M. Okadaic acid, useful tool for studying cellular processes. Curr Med Chem 9: 229–262, 2002.
11. + pump regulation. Circ Res 105: 185–193, 2009.
12. Follmer CH, ten Eick RE, Yeh JZ. Sodium current kinetics in cat atrial myocytes. J Physiol 384: 169–197, 1987.
13. Friebe A, Koesling D. Regulation of nitric oxide-sensitive guanylyl cyclase. Circ Res 93: 96–105, 2003.
14. + pump in cardiac myocytes and improves pulmonary congestion. Circulation 128: A17142, 2013.
15. Gadsby DC, Nakao M. Steady-state current-voltage relationship of the Na/K pump in guinea pig ventricular myocytes. J Gen Physiol 94: 511–537, 1989.
16. Gallogly MM, Starke DW, Mieyal JJ. Mechanistic and kinetic details of catalysis of thiol-disulfide exchange by glutaredoxins and potential mechanisms of regulation. Antioxid Redox Signal 11: 1059–1081, 2009.
17. + pump: evidence from in vivo and in vitro modulation of cell signalling. J Physiol 591: 2999–3015, 2013.
18. +-ATPase in cardiac myocytes. Biophys J 105: 2695–2705, 2013.
19. + ATPase. Biophys J 106: p427a, 2014.
20. Garrido AM, Griendling KK. NADPH oxidases and angiotensin II receptor signaling. Mol Cell Endocrinol 302: 148–158, 2009.
21. Harrison CB, Drummond GR, Sobey CG, Selemidis S. Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox-dependent mechanism in mice. Clin Exp Pharmacol Physiol 37: 429–434, 2010.
22. + pumping in cardiac myocytes. Am J Physiol Cell Physiol 268: C366–C375, 1995.
23. Irvine JC, Ganthavee V, Love JE, Alexander AE, Horowitz JD, Stasch JP, Kemp-Harper BK, Ritchie RH. The soluble guanylyl cyclase activator bay 58–2667 selectively limits cardiomyocyte hypertrophy. PLoS One 7: e44481, 2012.
24. + pump in Type 2 diabetes. Circulation 126: A16287, 2012.
25. Karimi Galougahi K, Liu CC, Gentile C, Kok C, Nunez A, Garcia A, Fry NAS, Davies MJ, Hawkins CL, Rasmussen HH, Figtree GA. Glutathionylation mediates Angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction. J Am Heart Assoc 3: e000731, 2014.
26. Kim YM, Guzik TJ, Zhang YH, Zhang MH, Kattach H, Ratnatunga C, Pillai R, Channon KM, Casadei B. A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation. Circ Res 97: 629–636, 2005.
27. Kimura T, Han W, Pagel P, Nairn AC, Caplan MJ. Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin. PLoS One 6: e29269, 2011.
28. Krafte DS, Kass RS. Hydrogen ion modulation of Ca channel current in cardiac ventricular cells. Evidence for multiple mechanisms. J Gen Physiol 91: 641–657, 1988.
29. Lassegue B, San Martin A, Griendling KK. Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ Res 110: 1364–1390, 2012.
30. Li JM, Shah AM. Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit. J Biol Chem 278: 12094–12100, 2003.
31. Lin EQ, Irvine JC, Cao AH, Alexander AE, Love JE, Patel R, McMullen JR, Kaye DM, Kemp-Harper BK, Ritchie RH. Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation. PLoS One 7: e34892, 2012.
32. + pump: new twists to an old target for treatment of heart failure. J Mol Cell Cardiol 61: 94–101, 2013.
33. + pump subunit to glutathionylation and oxidative inhibition depends on conformational state of pump. J Biol Chem 287: 12353–12364, 2012.
34. Martinez-Ruiz A, Cadenas S, Lamas S. Nitric oxide signaling: classical, less classical, and nonclassical mechanisms. Free Radic Biol Med 51: 17–29, 2011.
35. Mongillo M, Tocchetti CG, Terrin A, Lissandron V, Cheung YF, Dostmann WR, Pozzan T, Kass DA, Paolocci N, Houslay MD, Zaccolo M. Compartmentalized phosphodiesterase-2 activity blunts beta-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway. Circ Res 98: 226–234, 2006.
36. Mukhopadhyay A, Saddoughi SA, Song P, Sultan I, Ponnusamy S, Senkal CE, Snook CF, Arnold HK, Sears RC, Hannun YA, Ogretmen B. Direct interaction between the inhibitor 2 and ceramide via sphingolipid- protein binding is involved in the regulation of protein phosphatase 2A activity and signaling. FASEB J 23: 751–763, 2009.
37. Octavia Y, Brunner-La Rocca HP, Moens AL. NADPH oxidasedependent oxidative stress in the failing heart: From pathogenic roles to therapeutic approach. Free Radic Biol Med 52: 291–297, 2012.
38. +)-activated adenosine triphosphatase and amino-acid and carbohydrate analyses of the isolated subunits. Biochem J 192: 107–118, 1980.
39. +-ATPase activity in cultured rat skeletal muscle cells. J Biol Chem 272: 23653– 23658, 1997.
40. Sawyer DB, Siwik DA, Xiao L, Pimentel DR, Singh K, Colucci WS. Role of oxidative stress in myocardial hypertrophy and failure. J Mol Cell Cardiol 34: 379–388, 2002.
41. + pump via PKCdependent activation of NADPH oxidase. Am J Physiol Cell Physiol 296: C693–C700, 2009.
42. + pump and inhibits its activity. J Biol Chem 285: 13712–13720, 2010.
43. William M, Hamilton EJ, Garcia A, Bundgaard H, Chia KKM, Figtree GA, Rasmussen HH. Natriuretic peptides stimulate the cardiac sodium pump via NPR-C-coupled NOS activation. Am J Physiol Cell Physiol 294: C1067–C1073, 2008.
44. + pump in isolated rabbit cardiac myocytes. J Physiol 565: 815–825, 2005.
45. + currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells. J Biol Chem 271: 19760–19767, 1996.