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Volumn 142, Issue JULY, 2015, Pages 23-32

Alterations of mucosal microbiota in the colon of patients with inflammatory bowel disease revealed by real time polymerase chain reaction amplification of 16S ribosomal ribonucleic acid

Author keywords

Bacteroidetes; Crohn s disease; Dysbiosis; Firmicutes; Microbiota; Ulcerative colitis

Indexed keywords

MESALAZINE; METHOTREXATE; PURINE DERIVATIVE; RNA 16S; SALAZOSULFAPYRIDINE; STEROID;

EID: 84938704882     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: 10.4103/0971-5916.162091     Document Type: Article
Times cited : (109)

References (30)
  • 1
    • 84897628732 scopus 로고    scopus 로고
    • Role of the gut microbiota in human nutrition and metabolism
    • Ramakrishna BS. Role of the gut microbiota in human nutrition and metabolism. J Gastroenterol Hepatol 2013;28 (Suppl 4):9-17.
    • (2013) J Gastroenterol Hepatol , vol.28 , pp. 9-17
    • Ramakrishna, B.S.1
  • 3
    • 80054036384 scopus 로고    scopus 로고
    • Intestinal dysbiosis in inflammatory bowel disease
    • Kaur N, Chen CC, Luther J, Kao JY. Intestinal dysbiosis in inflammatory bowel disease. Gut Microbes 2011;2:211-6.
    • (2011) Gut Microbes , vol.2 , pp. 211-216
    • Kaur, N.1    Chen, C.C.2    Luther, J.3    Kao, J.Y.4
  • 4
    • 79952748335 scopus 로고    scopus 로고
    • The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions
    • Johansson ME, Larsson JM, Hansson GC. The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc Natl Acad Sci USA 2011;108 (Suppl 1):4659-65.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4659-4665
    • Johansson, M.E.1    Larsson, J.M.2    Hansson, G.C.3
  • 5
    • 78049501532 scopus 로고    scopus 로고
    • Real-time analysis of mucosal flora in patients with inflammatory bowel disease in India
    • Verma R, Verma AK, Ahuja V, Paul J. Real-time analysis of mucosal flora in patients with inflammatory bowel disease in India. J Clin Microbiol 2010;48:4279-82.
    • (2010) J Clin Microbiol , vol.48 , pp. 4279-4282
    • Verma, R.1    Verma, A.K.2    Ahuja, V.3    Paul, J.4
  • 6
    • 78650973052 scopus 로고    scopus 로고
    • High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease
    • Walker AW, Sanderson JD, Churcher C, Parkes GC, Hudspith BN, Rayment N, et al. High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease. BMC Microbiol 2011;11:7.
    • (2011) BMC Microbiol , vol.11 , pp. 7
    • Walker, A.W.1    Sanderson, J.D.2    Churcher, C.3    Parkes, G.C.4    Hudspith, B.N.5    Rayment, N.6
  • 7
    • 63849243189 scopus 로고    scopus 로고
    • Establishment of an analytical system for the human fecal microbiota, based on reverse transcriptionquantitative PCR targeting of multicopy rRNA molecules
    • Matsuda K, Tsuji H, Asahara T, Matsumoto K, Takada T, Nomoto K. Establishment of an analytical system for the human fecal microbiota, based on reverse transcriptionquantitative PCR targeting of multicopy rRNA molecules. Appl Environ Microbiol 2009;75:1961-9.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 1961-1969
    • Matsuda, K.1    Tsuji, H.2    Asahara, T.3    Matsumoto, K.4    Takada, T.5    Nomoto, K.6
  • 8
    • 33748792311 scopus 로고    scopus 로고
    • Temperature gradient gel electrophoresis of fecal 16S rRNA reveals active Escherichia coli in the microbiota of patients with ulcerative colitis
    • Sokol H, Lepage P, Seksik P, Doré J, Marteau P. Temperature gradient gel electrophoresis of fecal 16S rRNA reveals active Escherichia coli in the microbiota of patients with ulcerative colitis. J Clin Microbiol 2006;44:3172-7.
    • (2006) J Clin Microbiol , vol.44 , pp. 3172-3177
    • Sokol, H.1    Lepage, P.2    Seksik, P.3    Doré, J.4    Marteau, P.5
  • 10
    • 0036300743 scopus 로고    scopus 로고
    • Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces
    • Zoetendal EG, von Wright A, Vilpponen-Salmela T, Ben-Amor K, Akkermans AD, de Vos WM. Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces. Appl Environ Microbiol 2002;68:3401-7.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 3401-3407
    • Zoetendal, E.G.1    Von Wright, A.2    Vilpponen-Salmela, T.3    Ben-Amor, K.4    Akkermans, A.D.5    De Vos, W.M.6
  • 12
    • 55949124035 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
    • Sokol H, Pigneur B, Watterlot L, Lakhdari O, BermudezHumaran LG, Gratadoux JJ, et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA 2008;105:16731-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16731-16736
    • Sokol, H.1    Pigneur, B.2    Watterlot, L.3    Lakhdari, O.4    Bermudezhumaran, L.G.5    Gratadoux, J.J.6
  • 14
    • 9644268216 scopus 로고    scopus 로고
    • Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR
    • Rinttila T, Kassinen A, Malinen E, Krogius L, Palva A. Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR. J Appl Microbiol 2004;97:1166-77.
    • (2004) J Appl Microbiol , vol.97 , pp. 1166-1177
    • Rinttila, T.1    Kassinen, A.2    Malinen, E.3    Krogius, L.4    Palva, A.5
  • 15
    • 0345869650 scopus 로고    scopus 로고
    • Quantitative PCR with 16S rRNAgene-targeted species-specific primers for analysis of human intestinal bifidobacteria
    • Matsuki T, Watanabe K, Fujimoto J, Kado Y, Takada T, Matsumoto K, et al. Quantitative PCR with 16S rRNAgene-targeted species-specific primers for analysis of human intestinal bifidobacteria. Appl Environ Microbiol 2004;70:167-73.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 167-173
    • Matsuki, T.1    Watanabe, K.2    Fujimoto, J.3    Kado, Y.4    Takada, T.5    Matsumoto, K.6
  • 16
    • 48549084602 scopus 로고    scopus 로고
    • Real-time polymerase chain reaction quantification of specific butyrate-producing bacteria, Desulfovibrio and Enterococcus faecalis in the feces of patients with colorectal cancer
    • Balamurugan R, Rajendiran E, George S, Samuel GV, Ramakrishna BS. Real-time polymerase chain reaction quantification of specific butyrate-producing bacteria, Desulfovibrio and Enterococcus faecalis in the feces of patients with colorectal cancer. J Gastroenterol Hepatol 2008;23:1298-303.
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 1298-1303
    • Balamurugan, R.1    Rajendiran, E.2    George, S.3    Samuel, G.V.4    Ramakrishna, B.S.5
  • 18
    • 20444393973 scopus 로고    scopus 로고
    • Design and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota
    • Lay C, Sutren M, Rochet V, Saunier K, Dore J, Rigottier-Gois L. Design and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota. Environ Microbiol 2005;7:933-46.
    • (2005) Environ Microbiol , vol.7 , pp. 933-946
    • Lay, C.1    Sutren, M.2    Rochet, V.3    Saunier, K.4    Dore, J.5    Rigottier-Gois, L.6
  • 19
    • 78649622569 scopus 로고    scopus 로고
    • Dysbiosis of fecal microbiota in Crohn’s disease patients as revealed by a custom phylogenetic microarray
    • Kang S, Denman SE, Morrison M, Yu Z, Dore J, Leclerc M, et al. Dysbiosis of fecal microbiota in Crohn’s disease patients as revealed by a custom phylogenetic microarray. Inflamm Bowel Dis 2010;16:2034-42.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 2034-2042
    • Kang, S.1    Denman, S.E.2    Morrison, M.3    Yu, Z.4    Dore, J.5    Leclerc, M.6
  • 20
    • 79953748870 scopus 로고    scopus 로고
    • Dysbiosis of the faecal microbiota in patients with Crohn’s disease and their unaffected relatives
    • Joossens M, Huys G, Cnockaert M, De Preter V, Verbeke K, Rutgeerts P, et al. Dysbiosis of the faecal microbiota in patients with Crohn’s disease and their unaffected relatives. Gut 2011;60:631-7.
    • (2011) Gut , vol.60 , pp. 631-637
    • Joossens, M.1    Huys, G.2    Cnockaert, M.3    De Preter, V.4    Verbeke, K.5    Rutgeerts, P.6
  • 21
    • 4143069158 scopus 로고    scopus 로고
    • High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease
    • Darfeuille-Michaud A, Boudeau J, Bulois P, Neut C, Glasser AL, Barnich N, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease. Gastroenterology 2004;127:412-21.
    • (2004) Gastroenterology , vol.127 , pp. 412-421
    • Darfeuille-Michaud, A.1    Boudeau, J.2    Bulois, P.3    Neut, C.4    Glasser, A.L.5    Barnich, N.6
  • 23
    • 33747050143 scopus 로고    scopus 로고
    • The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn’s disease and ulcerative colitis patients
    • Bibiloni R, Mangold M, Madsen KL, Fedorak RN, Tannock GW. The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn’s disease and ulcerative colitis patients. J Med Microbiol 2006;55:1141-9.
    • (2006) J Med Microbiol , vol.55 , pp. 1141-1149
    • Bibiloni, R.1    Mangold, M.2    Madsen, K.L.3    Fedorak, R.N.4    Tannock, G.W.5
  • 24
    • 22144476548 scopus 로고    scopus 로고
    • Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease
    • Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H. Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol 2005;43:3380-9.
    • (2005) J Clin Microbiol , vol.43 , pp. 3380-3389
    • Swidsinski, A.1    Weber, J.2    Loening-Baucke, V.3    Hale, L.P.4    Lochs, H.5
  • 25
    • 33751556362 scopus 로고    scopus 로고
    • Abnormal microbiota composition in the ileocolonic mucosa of Crohn’s disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis
    • Martinez-Medina M, Aldeguer X, Gonzalez-Huix F, Acero D, Garcia-Gil LJ. Abnormal microbiota composition in the ileocolonic mucosa of Crohn’s disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis. Inflamm Bowel Dis 2006;12:1136-45.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 1136-1145
    • Martinez-Medina, M.1    Aldeguer, X.2    Gonzalez-Huix, F.3    Acero, D.4    Garcia-Gil, L.J.5
  • 26
    • 77956515952 scopus 로고    scopus 로고
    • Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients
    • Rehman A, Lepage P, Nolte A, Hellmig S, Schreiber S, Ott SJ. Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients. J Med Microbiol 2010;59:1114-22.
    • (2010) J Med Microbiol , vol.59 , pp. 1114-1122
    • Rehman, A.1    Lepage, P.2    Nolte, A.3    Hellmig, S.4    Schreiber, S.5    Ott, S.J.6
  • 27
    • 78650973052 scopus 로고    scopus 로고
    • High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease
    • Walker AW, Sanderson JD, Churcher C, Parkes GC, Hudspith BN, Rayment N, et al. High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease. BMC Microbiol 2011;11:7.
    • (2011) BMC Microbiol , vol.11 , pp. 7
    • Walker, A.W.1    Sanderson, J.D.2    Churcher, C.3    Parkes, G.C.4    Hudspith, B.N.5    Rayment, N.6
  • 28
    • 84859968477 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of the microbiota in ulcerated and nonulcerated regions in the patients with Crohn’s disease
    • Li Q, Wang C, Tang C, Li N, Li J. Molecular-phylogenetic characterization of the microbiota in ulcerated and nonulcerated regions in the patients with Crohn’s disease. PLoS One 2012;7:e34939.
    • (2012) Plos One , pp. 7
    • Li, Q.1    Wang, C.2    Tang, C.3    Li, N.4    Li, J.5
  • 29
    • 79956078164 scopus 로고    scopus 로고
    • Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease
    • 390403
    • Bloom SM, Bijanki VN, Nava GM, Sun L, Malvin NP, Donermeyer DL, et al. Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe 2011;9:390403.
    • (2011) Cell Host Microbe , pp. 9
    • Bloom, S.M.1    Bijanki, V.N.2    Nava, G.M.3    Sun, L.4    Malvin, N.P.5    Donermeyer, D.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.