Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II

Biochemistry

Volumn 54, Issue 31, 2015, Pages 4805-4814

  Mao, Yu ^a   Zlatic, Courtney O ^a   Griffin, Michael D W ^a   Howlett, Geoffrey J ^a   Todorova, Nevena ^b   Yarovsky, Irene ^b   Gooley, Paul R ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b RMIT UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ELECTRIC CHARGE; GLYCOPROTEINS; LIPOPROTEINS; OLIGOMERS; POLYPEPTIDES; X RAY DIFFRACTION;

FIBRIL FORMATION; FLUORESCENCE STUDIES; HYDROGEN/DEUTERIUM EXCHANGE; MOLECULAR DYNAMICS SIMULATIONS; PAIR INTERACTIONS; SOLVENT ACCESSIBILITY; STRUCTURAL MODELING; X-RAY DIFFRACTION DATA;

MOLECULAR DYNAMICS;

ACRYLAMIDE; AMYLOID; APOLIPOPROTEIN C2;

ARTICLE; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; FLUORESCENCE SPECTROSCOPY; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY DIFFRACTION; CHEMISTRY; GENETICS; METABOLISM; MISSENSE MUTATION; PROTEIN QUATERNARY STRUCTURE; SPECTROFLUOROMETRY;

AMYLOID; APOLIPOPROTEIN C-II; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; MOLECULAR DYNAMICS SIMULATION; MUTATION, MISSENSE; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SPECTROMETRY, FLUORESCENCE;

EID: 84938680564     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00535     Document Type: Article

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