Structural basis for the specificity of human NUDT16 and its regulation by inosine monophosphate

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Trésaugues, Lionel ^a   Lundbäck, Thomas ^a   Welin, Martin ^a   Flodin, Susanne ^a   Nyman, Tomas ^a   Silvander, Camilla ^a,c   Gräslund, Susanne ^a   Nordlund, Pär ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c Sprint Bioscience   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEOXYINOSINE DIPHOSPHATE; DIMER; GUANOSINE TRIPHOSPHATE; INOSINE PHOSPHATE; MESSENGER RNA; NUCLEOTIDE; NUDIX HYDROLASE; NUDT16 PROTEIN; PROTEIN; PYROPHOSPHATE; UNCLASSIFIED DRUG; ADENOSINE DIPHOSPHATE; INORGANIC PYROPHOSPHATASE; NUDT16 PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIMERIZATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HUMAN; HYDROGEN BOND; HYDROLYSIS; ISOTHERMAL TITRATION CALORIMETRY; NUCLEOTIDE METABOLISM; PROTEIN BINDING; PROTEIN STRUCTURE; BIOCATALYSIS; CALORIMETRY; CHEMISTRY; CONSERVED SEQUENCE; DRUG EFFECTS; KINETICS; METABOLISM; PROTEIN MULTIMERIZATION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; BIOCATALYSIS; CALORIMETRY; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HUMANS; INOSINE MONOPHOSPHATE; KINETICS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PYROPHOSPHATASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84938679644     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131507     Document Type: Article

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