-
1
-
-
0035708568
-
Cellular mechanisms of nicotine addiction
-
Dani JA, De Biasi M. Cellular mechanisms of nicotine addiction. Pharmacol Biochem Behav 2001; 70: 439-446
-
(2001)
Pharmacol Biochem Behav
, vol.70
, pp. 439-446
-
-
Dani, J.A.1
De Biasi, M.2
-
2
-
-
42649091460
-
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
-
Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 2008; 40: 616-622
-
(2008)
Nat Genet
, vol.40
, pp. 616-622
-
-
Amos, C.I.1
Wu, X.2
Broderick, P.3
Gorlov, I.P.4
Gu, J.5
Eisen, T.6
-
3
-
-
40849097777
-
Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking
-
Berrettini W, Yuan X, Tozzi F, Song K, Francks C, Chilcoat H et al. Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Mol Psychiatry 2008; 13: 368-373
-
(2008)
Mol Psychiatry
, vol.13
, pp. 368-373
-
-
Berrettini, W.1
Yuan, X.2
Tozzi, F.3
Song, K.4
Francks, C.5
Chilcoat, H.6
-
4
-
-
51349156208
-
Variants in nicotinic receptors and risk for nicotine dependence
-
Bierut LJ, Stitzel JA, Wang JC, Hinrichs AL, Grucza RA, Xuei X et al. Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry 2008; 165: 1163-1171
-
(2008)
Am J Psychiatry
, vol.165
, pp. 1163-1171
-
-
Bierut, L.J.1
Stitzel, J.A.2
Wang, J.C.3
Hinrichs, A.L.4
Grucza, R.A.5
Xuei, X.6
-
5
-
-
84864279400
-
Genome-wide and candidate gene association study of cigarette smoking behaviors
-
Caporaso N, Gu F, Chatterjee N, Sheng-Chih J, Yu K, Yeager M et al. Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One 2009; 4: e4653
-
(2009)
PLoS One
, vol.4
, pp. e4653
-
-
Caporaso, N.1
Gu, F.2
Chatterjee, N.3
Sheng-Chih, J.4
Yu, K.5
Yeager, M.6
-
6
-
-
84863905020
-
Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success
-
Chen LS, Baker TB, Piper ME, Breslau N, Cannon DS, Doheny KF et al. Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success. Am J Psychiatry 2012; 169: 735-742
-
(2012)
Am J Psychiatry
, vol.169
, pp. 735-742
-
-
Chen, L.S.1
Baker, T.B.2
Piper, M.E.3
Breslau, N.4
Cannon, D.S.5
Doheny, K.F.6
-
7
-
-
41649103682
-
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
-
Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 2008; 452: 633-637
-
(2008)
Nature
, vol.452
, pp. 633-637
-
-
Hung, R.J.1
McKay, J.D.2
Gaborieau, V.3
Boffetta, P.4
Hashibe, M.5
Zaridze, D.6
-
8
-
-
63449101907
-
A genome-wide association study in chronic obstructive pulmonary disease (COPD): Identification of two major susceptibility loci
-
Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC et al. A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet 2009; 5: e1000421
-
(2009)
PLoS Genet
, vol.5
, pp. e1000421
-
-
Pillai, S.G.1
Ge, D.2
Zhu, G.3
Kong, X.4
Shianna, K.V.5
Need, A.C.6
-
9
-
-
33846510020
-
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
-
Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA et al. Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet 2007; 16: 36-49
-
(2007)
Hum Mol Genet
, vol.16
, pp. 36-49
-
-
Saccone, S.F.1
Hinrichs, A.L.2
Saccone, N.L.3
Chase, G.A.4
Konvicka, K.5
Madden, P.A.6
-
10
-
-
41649103052
-
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
-
Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, Magnusson KP et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 2008; 452: 638-642
-
(2008)
Nature
, vol.452
, pp. 638-642
-
-
Thorgeirsson, T.E.1
Geller, F.2
Sulem, P.3
Rafnar, T.4
Wiste, A.5
Kp, M.6
-
11
-
-
77951751034
-
Meta-Analysis and imputation refines the association of 15q25 with smoking quantity
-
Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L et al. Meta-Analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 2010; 42: 436-440
-
(2010)
Nat Genet
, vol.42
, pp. 436-440
-
-
Liu, J.Z.1
Tozzi, F.2
Waterworth, D.M.3
Pillai, S.G.4
Muglia, P.5
Middleton, L.6
-
12
-
-
77951748276
-
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
-
Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010; 42: 448-453
-
(2010)
Nat Genet
, vol.42
, pp. 448-453
-
-
Thorgeirsson, T.E.1
Gudbjartsson, D.F.2
Surakka, I.3
Vink, J.M.4
Amin, N.5
Geller, F.6
-
13
-
-
77951711343
-
Genome-wide meta-Analyses identify multiple loci associated with smoking behavior
-
Tobacco Genetics Consortium
-
Tobacco and Genetics Consortium. Genome-wide meta-Analyses identify multiple loci associated with smoking behavior. Nat Genet 2010; 42: 441-447
-
(2010)
Nat Genet
, vol.42
, pp. 441-447
-
-
-
14
-
-
84860333167
-
Smoking and genetic risk variation across populations of European Asian, and African American ancestry-A meta-Analysis of chromosome 15q25
-
Chen LS, Saccone NL, Culverhouse RC, Bracci PM, Chen CH, Dueker N et al. Smoking and genetic risk variation across populations of European, Asian, and African American ancestry-A meta-Analysis of chromosome 15q25. Genet Epidemiol 2012; 36: 340-351
-
(2012)
Genet Epidemiol
, vol.36
, pp. 340-351
-
-
Chen, L.S.1
Saccone, N.L.2
Culverhouse, R.C.3
Bracci, P.M.4
Ch, C.5
Dueker, N.6
-
15
-
-
70149090145
-
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans
-
Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF et al. The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. Cancer Res 2009; 69: 6848-6856
-
(2009)
Cancer Res
, vol.69
, pp. 6848-6856
-
-
Saccone, N.L.1
Wang, J.C.2
Breslau, N.3
Johnson, E.O.4
Hatsukami, D.5
Saccone, S.F.6
-
16
-
-
78651336831
-
Acetylcholine receptor (AChR) alpha5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (alpha4beta2)alpha5 AChR function
-
Kuryatov A, Berrettini W, Lindstrom J. Acetylcholine receptor (AChR) alpha5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (alpha4beta2)alpha5 AChR function. Mol Pharmacol 2011; 79: 119-125
-
(2011)
Mol Pharmacol
, vol.79
, pp. 119-125
-
-
Kuryatov, A.1
Berrettini, W.2
Lindstrom, J.3
-
17
-
-
33846536406
-
Novel genes identified in a high-density genome wide association study for nicotine dependence
-
Bierut LJ, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau OF et al. Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet 2007; 16: 24-35
-
(2007)
Hum Mol Genet
, vol.16
, pp. 24-35
-
-
Bierut, L.J.1
Madden, P.A.2
Breslau, N.3
Johnson, E.O.4
Hatsukami, D.5
Pomerleau, O.F.6
-
18
-
-
0025923219
-
The Fagerstrom Test for Nicotine Dependence: A revision of the Fagerstrom Tolerance Questionnaire
-
Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 1991; 86: 1119-1127
-
(1991)
Br J Addict
, vol.86
, pp. 1119-1127
-
-
Heatherton, T.F.1
Kozlowski, L.T.2
Frecker, R.C.3
Fagerstrom, K.O.4
-
19
-
-
77956534324
-
ANNOVAR: Functional annotation of genetic variants from high-Throughput sequencing data
-
Wang K, Li M, Hakonarson H. ANNOVAR: functional annotation of genetic variants from high-Throughput sequencing data. Nucleic Acids Res 2010; 38: e164
-
(2010)
Nucleic Acids Res
, vol.38
, pp. e164
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
20
-
-
84975795680
-
An integrated map of genetic variation from 1, 092 human genomes
-
Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE et al. An integrated map of genetic variation from 1, 092 human genomes. Nature 2012; 491: 56-65
-
(2012)
Nature
, vol.491
, pp. 56-65
-
-
Abecasis, G.R.1
Auton, A.2
Brooks, L.D.3
Ma, D.4
Durbin, R.M.5
Handsaker, R.E.6
-
21
-
-
79953715693
-
Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel
-
Gonzalez-Perez A, Lopez-Bigas N. Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel. Am J Hum Genet 2011; 88: 440-449
-
(2011)
Am J Hum Genet
, vol.88
, pp. 440-449
-
-
Gonzalez-Perez, A.1
Lopez-Bigas, N.2
-
22
-
-
84856079279
-
Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence
-
Haller G, Druley T, Vallania FL, Mitra RD, Li P, Akk G et al. Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence. Hum Mol Genet 2012; 21: 647-655
-
(2012)
Hum Mol Genet
, vol.21
, pp. 647-655
-
-
Haller, G.1
Druley, T.2
Vallania, F.L.3
Mitra, R.D.4
Li, P.5
Akk, G.6
-
23
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006; 38: 904-909
-
(2006)
Nat Genet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
24
-
-
50949095168
-
Methods for detecting associations with rare variants for common diseases: Application to analysis of sequence data
-
Li B, Leal SM. Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am J Hum Genet 2008; 83: 311-321
-
(2008)
Am J Hum Genet
, vol.83
, pp. 311-321
-
-
Li, B.1
Leal, S.M.2
-
25
-
-
77956887506
-
A note on a general definition of the coefficient of determination
-
Nagelkerke N. A note on a general definition of the coefficient of determination. Biometrika 1991; 78: 691-692
-
(1991)
Biometrika
, vol.78
, pp. 691-692
-
-
Nagelkerke, N.1
-
26
-
-
57449114734
-
Nicotinic receptor gene variants influence susceptibility to heavy smoking
-
Stevens VL, Bierut LJ, Talbot JT, Wang JC, Sun J, Hinrichs AL et al. Nicotinic receptor gene variants influence susceptibility to heavy smoking. Cancer Epidemiol Biomarkers Prev 2008; 17: 3517-3525
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 3517-3525
-
-
Stevens, V.L.1
Bierut, L.J.2
Talbot, J.T.3
Wang, J.C.4
Sun, J.5
Hinrichs, A.L.6
-
27
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-575
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ma, F.5
Bender, D.6
-
28
-
-
84899956833
-
Identification of CHRNA5 rare variants in African-American heavy smokers
-
Doyle GA, Chou AD, Saung WT, Lai AT, Lohoff FW, Berrettini WH. Identification of CHRNA5 rare variants in African-American heavy smokers. Psychiatr Genet 2014; 24: 102-109
-
(2014)
Psychiatr Genet
, vol.24
, pp. 102-109
-
-
Doyle, G.A.1
Chou, A.D.2
Saung, W.T.3
Lai, A.T.4
Lohoff, F.W.5
Berrettini, W.H.6
-
29
-
-
84899537963
-
Rare nonsynonymous exonic variants in addiction and behavioral disinhibition
-
Vrieze SI, Feng S, Miller MB, Hicks BM, Pankratz N, Abecasis GR et al. Rare nonsynonymous exonic variants in addiction and behavioral disinhibition. Biol Psychiatry 2014; 75: 783-789
-
(2014)
Biol Psychiatry
, vol.75
, pp. 783-789
-
-
Vrieze, S.I.1
Feng, S.2
Miller, M.B.3
Hicks, B.M.4
Pankratz, N.5
Abecasis, G.R.6
-
30
-
-
77958012303
-
Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstrom test for nicotine dependence
-
Wessel J, McDonald SM, Hinds DA, Stokowski RP, Javitz HS, Kennemer M et al. Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstrom test for nicotine dependence. Neuropsychopharmacology 2010; 35: 2392-2402
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 2392-2402
-
-
Wessel, J.1
McDonald, S.M.2
Hinds, D.A.3
Stokowski, R.P.4
Javitz, H.S.5
Kennemer, M.6
-
31
-
-
55549147191
-
Personal genomes: The case of the missing heritability
-
Maher B. Personal genomes: The case of the missing heritability. Nature 2008; 456: 18-21
-
(2008)
Nature
, vol.456
, pp. 18-21
-
-
Maher, B.1
-
32
-
-
70349573295
-
Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15
-
Keskitalo K, Broms U, Heliovaara M, Ripatti S, Surakka I, Perola M et al. Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. Hum Mol Genet 2009; 18: 4007-4012
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4007-4012
-
-
Keskitalo, K.1
Broms, U.2
Heliovaara, M.3
Ripatti, S.4
Surakka, I.5
Perola, M.6
-
33
-
-
84911870094
-
Beyond cigarettes per day A genome-wide association study of the biomarker carbon monoxide
-
Bloom AJ, Hartz SM, Baker TB, Chen LS, Piper ME, Fox L et al. Beyond cigarettes per day. A genome-wide association study of the biomarker carbon monoxide. Ann Am Thorac Soc 2014; 11: 1003-1010
-
(2014)
Ann Am Thorac Soc
, vol.11
, pp. 1003-1010
-
-
Bloom, A.J.1
Hartz, S.M.2
Baker, T.B.3
Chen, L.S.4
Piper, M.E.5
Fox, L.6
-
34
-
-
84861325364
-
Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure
-
Munafo MR, Timofeeva MN, Morris RW, Prieto-Merino D, Sattar N, Brennan P et al. Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. J Natl Cancer Inst 2012; 104: 740-748
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 740-748
-
-
Munafo, M.R.1
Timofeeva, M.N.2
Morris, R.W.3
Prieto-Merino, D.4
Sattar, N.5
Brennan, P.6
-
35
-
-
68049090045
-
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5
-
Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP et al. Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet 2009; 18: 3125-3135
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3125-3135
-
-
Wang, J.C.1
Cruchaga, C.2
Saccone, N.L.3
Bertelsen, S.4
Liu, P.5
Budde, J.P.6
-
36
-
-
65349161502
-
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence
-
Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, Budde JP et al. Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Mol Psychiatry 2009; 14: 501-510
-
(2009)
Mol Psychiatry
, vol.14
, pp. 501-510
-
-
Wang, J.C.1
Grucza, R.2
Cruchaga, C.3
Hinrichs, A.L.4
Bertelsen, S.5
Budde, J.P.6
-
37
-
-
84896731443
-
Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry
-
Wang JC, Spiegel N, Bertelsen S, Le N, McKenna N, Budde JP et al. Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry. PLoS One 2013; 8: e80204
-
(2013)
PLoS One
, vol.8
, pp. e80204
-
-
Wang, J.C.1
Spiegel, N.2
Bertelsen, S.3
Le McKenna N, N.4
Budde, J.P.5
-
38
-
-
78649627035
-
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans
-
Saccone NL, Schwantes-An TH, Wang JC, Grucza RA, Breslau N, Hatsukami D et al. Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. Genes Brain Behav 2010; 9: 741-750
-
(2010)
Genes Brain Behav
, vol.9
, pp. 741-750
-
-
Saccone, N.L.1
Schwantes-An, T.H.2
Wang, J.C.3
Grucza, R.A.4
Breslau, N.5
Hatsukami, D.6
|