Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: A randomized, open-label, prospective trial

Oncotarget

Volumn 6, Issue 20, 2015, Pages 18162-18173

  Wang, Jack P ^a,b,c   Wu, Chen Yi ^a,b,c   Yeh, Yi Cheng ^a,b   Shyr, Yi Ming ^a,b   Wu, Ying Ying ^a,b   Kuo, Chen Yu ^a,b   Hung, Yi Ping ^a,b   Chen, Ming Huang ^a,b   Lee, Wei Ping ^a,b   Luo, Jiing Chyuan ^a,b   Chao, Yee ^a,b   Li, Chung Pin ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Adenocarcinoma; Epidermal growth factor receptor; Erlotinib; Pancreas

Indexed keywords

ALANINE AMINOTRANSFERASE; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEMCITABINE; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; EGFR PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; PROTEIN P21;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DIARRHEA; DISEASE CONTROL; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EGFR GENE; FEBRILE NEUTROPENIA; FEMALE; FEVER; GENE MUTATION; HUMAN; INTERSTITIAL LUNG DISEASE; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; METASTASIS; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; ONCOGENE K RAS; OPEN STUDY; OVERALL SURVIVAL; PANCREAS CANCER; PHASE 2 CLINICAL TRIAL; PROGRESSION FREE SURVIVAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RASH; STOMATITIS; THROMBOCYTOPENIA; TREATMENT RESPONSE; VOMITING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CLINICAL TRIAL; COMPARATIVE STUDY; DISEASE FREE SURVIVAL; DNA MUTATIONAL ANALYSIS; ENZYMOLOGY; GENETICS; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MORTALITY; MUTATION; PANCREATIC NEOPLASMS; PATHOLOGY; TAIWAN; TIME FACTOR; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DEOXYCYTIDINE; DISEASE-FREE SURVIVAL; DNA MUTATIONAL ANALYSIS; ERLOTINIB HYDROCHLORIDE; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MUTATION; PANCREATIC NEOPLASMS; PROSPECTIVE STUDIES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS P21(RAS); RECEPTOR, EPIDERMAL GROWTH FACTOR; TAIWAN; TIME FACTORS; TREATMENT OUTCOME;

EID: 84938632405     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4216     Document Type: Article

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