DEPDC1 is a novel cell cycle related gene that regulates mitotic progression

BMB Reports

Volumn 48, Issue 7, 2015, Pages 413-418

  Mi, Yan ^a   Zhang, Chundong ^b   Bu, Youquan ^b   Zhang, Ying ^b   He, Longxia ^a,b   Li, Hongxia ^a,b   Zhu, Huifang ^b   Li, Yi ^b   Lei, Yunlong ^b   Zhu, Jiang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Cancer; Cell cycle; DEPDC1; Mitosis; Nuclear protein

Indexed keywords

DEPDC1 PROTEIN, HUMAN; DNA BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NUCLEAR PROTEIN; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TNFAIP3 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 3; TUMOR PROTEIN;

CELL CYCLE CHECKPOINT; CELL FRACTIONATION; CENTROSOME; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GENETICS; HELA CELL LINE; HUMAN; METABOLISM; MITOSIS; PROTEIN TRANSPORT; UPREGULATION;

CELL CYCLE CHECKPOINTS; CENTROSOME; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKDOWN TECHNIQUES; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOSIS; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; SUBCELLULAR FRACTIONS; TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3; UP-REGULATION;

EID: 84938596925     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2015.48.7.036     Document Type: Article

References (20)

1. Kanehira M, Harada Y, Takata R et al (2007) Involvement of upregulation of DEPDC1 (DEP domain containing 1) in bladder carcinogenesis. Oncogene 26, 6448-6455
2. Harada Y, Kanehira M, Fujisawa Y et al (2010) Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells. Cancer Res 70, 5829-5839
3. Obara W, Ohsawa R, Kanehira M et al (2012) Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer. Jpn J Clin Oncol 42, 591-600
4. Kretschmer C, Sterner-Kock A, Siedentopf F et al (2011) Identification of early molecular markers for breast cancer. Mol Cancer 10, 15
5. Kassambara A, Schoenhals M, Moreaux J et al (2013) Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells. PLoS One 8, e62752
6. Yuan SG, Liao WJ, Yang JJ et al (2014) DEP Domain Containing 1 is a Novel Diagnostic Marker and Prognostic Predictor for Hepatocellular Carcinoma. Asian Pac J Cancer Prev 15, 10917-10922
7. Okayama H, Kohno T, Ishii Y et al (2012) Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALKnegative lung adenocarcinomas. Cancer Res 72, 100-111
8. Sendoel A, Maida S, Zheng X et al (2014) DEPDC1/ LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis. Nat Cell Biol 16, 812-820
9. Denning DP and Hirose T (2014) Anti-tubulins DEPendably induce apoptosis. Nat Cell Biol 16, 741-743
10. Williams GH and Stoeber K (2012) The cell cycle and cancer. J Pathol 226, 352-364
11. Malumbres M and Carnero A (2003) Cell cycle deregulation:a common motif in cancer. Prog Cell Cycle Res 5, 5-18
12. Perez de Castro I, de Carcer G, Malumbres M (2007) A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy. Carcinogenesis 28, 899-912
13. Ji Y, Xie M, Lan H et al (2013)PRR11 is a novel gene implicated in cell cycle progression and lung cancer. Int J Biochem Cell Biol 45, 645-656
14. Bu Y, Suenaga Y, Okoshi R et al (2010) NFBD1/MDC1 participates in the regulation of G2/M transition in mammalian cells. Biochem Biophys Res Commun 397, 157-162
15. Livak KJ and Schmittgen TD (2001)Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408
16. Prajapati S, Tu Z, Yamamoto Y et al (2006) IKK α regulates the mitotic phase of the cell cycle by modulating Aurora A phosphorylation. Cell Cycle 5, 2371-2380
17. Cude K, Wang Y, Choi HJ et al (2007) Regulation of the G2-M cell cycle progression by the ERK5-NFΚB signaling pathway. J Cell Biol 177, 253-264
18. Ledoux AC and Perkins ND (2014) NF-ΚB and the cell cycle. Biochem Soc Trans 42, 76-81
19. Ribas VT, Gonçalves BS, Linden R et al (2012) Activation of c-Jun N-terminal kinase (JNK) during mitosis in retinal progenitor cells. PLoS One 7, e34483
20. Almuedo-Castillo M, Crespo X, Seebeck F et al (2014) JNK controls the onset of mitosis in planarian stem cells and triggers apoptotic cell death required for regeneration and remodeling. PLoS Genet 10, e1004400