DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis

Nature Cell Biology

Volumn 16, Issue 8, 2014, Pages 812-820

  Sendoel, Ataman ^a,b,f,g   Maida, Simona ^c   Zheng, Xue ^a   Teo, Youjin ^a   Stergiou, Lilli ^a,f   Rossi, Carlo Alberto ^c   Subasic, Deni ^a   Pinto, Sergio M ^a   Kinchen, Jason M ^d   Shi, Moyin ^a   Boettcher, Steffen ^b   Meyer, Joel N ^e   Manz, Markus G ^b   Bano, Daniele ^c   Hengartner, Michael O ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d UNIVERSITY OF VIRGINIA   (United States)

^e DUKE UNIVERSITY   (United States)

^f ROCKEFELLER UNIVERSITY   (United States)

^g Redbiotec   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DNA; DOXORUBICIN; ETOPOSIDE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MEMBRANE PROTEIN; PROTEIN DEPDC1; PROTEIN LET 99; PROTEIN MCL 1; PROTEIN MCL 2; RNA; STRESS ACTIVATED PROTEIN KINASE; TUBULIN; UNCLASSIFIED DRUG; VINCRISTINE; CAENORHABDITIS ELEGANS PROTEIN; CED-13 PROTEIN, C ELEGANS; DEPDC1 PROTEIN, HUMAN; EGL-1 PROTEIN, C ELEGANS; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; LET-99 PROTEIN, C ELEGANS; MCL1 PROTEIN, HUMAN; MYELOID LEUKEMIA FACTOR 1; REPRESSOR PROTEIN; TUBULIN MODULATOR; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE ARREST; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPDC1 GENE; DNA DAMAGE; ENZYME ACTIVATION; ENZYME DEGRADATION; GENE; GENE IDENTIFICATION; GENE SILENCING; GENETIC SCREENING; HUMAN; HUMAN CELL; IN VIVO STUDY; IONIZING RADIATION; LET 99 GENE; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; DRUG EFFECTS; GENETICS; HELA CELL LINE; MCF 7 CELL LINE; METABOLISM; MICROTUBULE; MOLECULAR EVOLUTION; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN DEGRADATION;

CAENORHABDITIS ELEGANS;

ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EVOLUTION, MOLECULAR; GENES, HELMINTH; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MCF-7 CELLS; MICROTUBULES; MUTATION; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEOLYSIS; REPRESSOR PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUBULIN MODULATORS; VINCRISTINE;

EID: 84905397039     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3010     Document Type: Article

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