Addicted to AA (Acetoacetate): A Point of Convergence between Metabolism and BRAF Signaling

Molecular Cell

Volumn 59, Issue 3, 2015, Pages 333-334

  Trousil, Sebastian ^a   Zheng, Bin ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ACETOACETIC ACID; B RAF KINASE; HYDROXYMETHYLGLUTARYL COENZYME A LYASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; LYASE; OCTAMER TRANSCRIPTION FACTOR 1;

CELL GROWTH; CELL METABOLISM; CELL SURVIVAL; FATTY ACID OXIDATION; GLUCOSE METABOLISM; HUMAN; KETOGENESIS; METABOLIC REGULATION; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; PROTEIN PROCESSING; SHORT SURVEY; SIGNAL TRANSDUCTION; UPREGULATION; HAIRY CELL LEUKEMIA; MELANOMA; METABOLISM;

HUMANS; LEUKEMIA, HAIRY CELL; MAP KINASE KINASE 1; MELANOMA; OCTAMER TRANSCRIPTION FACTOR-1; OXO-ACID-LYASES; PROTO-ONCOGENE PROTEINS B-RAF; SIGNAL TRANSDUCTION;

EID: 84938574498     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.07.024     Document Type: Short Survey

References (10)

1. Bollag G., Hirth P., Tsai J., Zhang J., Ibrahim P.N., Cho H., Spevak W., Zhang C., Zhang Y., Habets G., et al. Nature 2010, 467:596-599.
2. Desideri E., Cavallo A.L., Baccarini M. Cell 2015, 161:967-970.
3. Gomes A.P., Blenis J. Curr. Opin. Biotechnol. 2015, 34C:110-117.
4. Joseph E.W., Pratilas C.A., Poulikakos P.I., Tadi M., Wang W., Taylor B.S., Halilovic E., Persaud Y., Xing F., Viale A., et al. Proc. Natl. Acad. Sci. USA 2010, 107:14903-14908.
5. Kang H.-B., Fan J., Lin R., Elf S., Ji Q., Zhao L., et al. Mol. Cell 2015, 59:345-358. this issue.
6. Maekawa T., Sano Y., Shinagawa T., Rahman Z., Sakuma T., Nomura S., Licht J.D., Ishii S. Oncogene 2008, 27:1045-1054.
7. Parmenter T.J., Kleinschmidt M., Kinross K.M., Bond S.T., Li J., Kaadige M.R., Rao A., Sheppard K.E., Hugo W., Pupo G.M., et al. Cancer Discov. 2014, 4:423-433.
8. Saraon P., Cretu D., Musrap N., Karagiannis G.S., Batruch I., Drabovich A.P., van der Kwast T., Mizokami A., Morrissey C., Jarvi K., Diamandis E.P. Mol. Cell. Proteomics 2013, 12:1589-1601.
9. Stuart S.A., Houel S., Lee T., Wang N., Old W.M., Ahn N.G. Mol. Cell. Proteomics 2015, 14:1599-1615.
10. Zheng B., Jeong J.H., Asara J.M., Yuan Y.-Y., Granter S.R., Chin L., Cantley L.C. Mol. Cell 2009, 33:237-247.