Vitamin D deficiency is associated with increased risk of Alzheimer's disease and dementia: Evidence from meta-analysis

Nutrition Journal

Volumn 14, Issue 1, 2015, Pages

  Shen, Liang ^a   Ji, Hong Fang ^a  

^a SHANDONG UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; VITAMIN D;

ALZHEIMER DISEASE; ARTICLE; DEMENTIA; DISEASE ASSOCIATION; HUMAN; INCIDENCE; META ANALYSIS; RISK FACTOR; SYSTEMATIC REVIEW; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; BLOOD; COMPLICATION; DIETARY SUPPLEMENT;

ALZHEIMER DISEASE; DEMENTIA; DIETARY SUPPLEMENTS; HUMANS; RISK FACTORS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84938573359     PISSN: None     EISSN: 14752891     Source Type: Journal    
DOI: 10.1186/s12937-015-0063-7     Document Type: Article

References (28)

1. Alzheimer's Association. 2014 Alzheimer's disease facts and figures. Alzheimers Dement. 2014;10:e47-92.
2. Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM. Forecasting the global burden of Alzheimer's disease. Alzheimers Dement. 2007;3:186-91.
3. Gezen-Ak D, Yilmazer S, Dursun E. Why vitamin D in Alzheimer's disease? The hypothesis. J Alzheimers Dis. 2014;40:257-69.
4. Morley JE. Dementia: does vitamin D modulate cognition? Nat Rev Neurol. 2014;10:613-4.
5. Pogge E. Vitamin D, and Alzheimer's disease: is there a link? Consult Pharm. 2010;25:440-50.
6. Evatt ML, DeLong MR, Khazai N, Rosen A, Triche S, Tangpricha V. Prevalence of vitamin D insufficiency in patients with Parkinson disease and Alzheimer disease. Arch Neurol. 2008;65:1348-52.
7. Sato Y, Asoh T, Oizumi K. High prevalence of vitamin D deficiency and reduced bone mass in elderly women with Alzheimer's disease. Bone. 1998;23:555-7.
8. Zhao Y, Sun Y, Ji HF, Shen L. Vitamin D levels in Alzheimer's and Parkinson's diseases: a meta-analysis. Nutrition. 2013;29:828-32.
9. Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PH, et al. Vitamin D and the risk of dementia and Alzheimer disease. Neurology. 2014;83:920-8.
10. Afzal S, Bojesen SE, Nordestgaard BG. Reduced 25-hydroxyvitamin D and risk of Alzheimer's disease and vascular dementia. Alzheimers Dement. 2014;10:296-302.
11. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266-81.
12. Buell JS, Dawson-Hughes B, Scott TM, Weiner DE, Dallal GE, Qui WQ, et al. 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology. 2010;74:18-26.
13. Annweiler C, Fantino B, Le Gall D, Schott AM, Berrut G, Beauchet O. Severe vitamin D deficiency is associated with advanced-stage dementia in geriatric inpatients. J Am Geriatr Soc. 2011;59:169-71.
14. Nagel G, Herbolsheimer F, Riepe M, Nikolaus T, Denkinger MD, Peter R, et al. Serum Vitamin D concentrations and cognitive function in a population-based study among older adults in South Germany. J Alzheimers Dis. 2015;45:1119-26.
15. Zittermann A. Vitamin D, and cardiovascular disease. Anticancer Res. 2014;34:4641-8.
16. Muscogiuri G, Mitri J, Mathieu C, Badenhoop K, Tamer G, Orio F, et al. Mechanisms in endocrinology: vitamin D as a potential contributor in endocrine health and disease. Eur J Endocrinol. 2014;171:R101-10.
17. Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004;79:362-71.
18. Dickens AP, Lang IA, Langa KM, Kos K, Llewellyn DJ. Vitamin D, cognitive dysfunction and dementia in older adults. CNS Drugs. 2011;25:629-39.
19. Schlögl M, Holick MF. Vitamin D and neurocognitive function. Clin Interv Aging. 2014;9:559-68.
20. Knekt P, Sääksjärvi K, Järvinen R, Marniemi J, Mönnistö S, Kanerva N, et al. Serum 25-hydroxyvitamin d concentration and risk of dementia. Epidemiology. 2014;25:799-804.
21. Annweiler C, Schott AM, Berrut G, Chauvire V, Le Gall D, Inzitari M, et al. Vitamin D and ageing: neurological issues. Neuropsychobiology. 2010;62:139-50.
22. Etgen T, Sander D, Bickel H, Sander K, Förstl H. Vitamin D deficiency, cognitive impairment and dementia: a systematic review and meta-analysis. Dement Geriatr Cogn Disord. 2012;33:297-305.
23. Balion C, Griffith LE, Strifler L, Henderson M, Patterson C, Heckman G, et al. Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology. 2012;79:1397-405.
24. Annweiler C, Rolland Y, Schott AM, Blain H, Vellas B, Herrmann FR, et al. Higher vitamin D dietary intake is associated with lower risk of alzheimer's disease: a 7-year follow-up. J Gerontol A Biol Sci Med Sci. 2012;67:1205-11.
25. Taghizadeh M, Talaei SA, Djazayeri A, Salami M. Vitamin D supplementation restores suppressed synaptic plasticity in Alzheimer's disease. Nutr Neurosci. 2014;17:172-7.
26. Rossom RC, Espeland MA, Manson JE, Dysken MW, Johnson KC, Lane DS, et al. Calcium and vitamin D supplementation and cognitive impairment in the women's health initiative. J Am Geriatr Soc. 2012;60:2197-205.
27. Seshadri S, Wolf PA, Beiser A, Au R, McNulty K, White R, et al. Lifetime risk of dementia and Alzheimer's disease: the impact of mortality on risk estimates in the Framingham study. Neurology. 1997;49:1498-504.
28. Miech RA, Breitner JC, Zandi PP, Khachaturian AS, Anthony JC, Mayer L. Incidence of AD may decline in the early 90s for men, later for women: the Cache County study. Neurology. 2002;58:209-18.