Vitamin D and the risk of dementia and Alzheimer disease

Neurology

Volumn 83, Issue 10, 2014, Pages 920-928

  Littlejohns, Thomas J ^a   Henley, William E ^a   Lang, Iain A ^a   Annweiler, Cedric ^b   Beauchet, Olivier ^b   Chaves, Paulo H M ^c   Fried, Linda ^d   Kestenbaum, Bryan R ^e   Kuller, Lewis H ^f   Langa, Kenneth M ^h,i   Lopez, Oscar L ^g   Kos, Katarina ^a   Soni, Maya ^a   Llewellyn, David J ^a  

^a UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^d Columbia University ^*  (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^g UNIVERSITY OF PITTSBURGH   (United States)

^h VETERANS AFFAIRS MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; 25-HYDROXYVITAMIN D; VITAMIN D;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BLOOD ANALYSIS; DEMENTIA; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; UNITED STATES; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; ANALOGS AND DERIVATIVES; BLOOD; COMPLICATION; FOLLOW UP; INCIDENCE; PROPORTIONAL HAZARDS MODEL;

AGED; ALZHEIMER DISEASE; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; UNITED STATES; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84905491891     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000000755     Document Type: Article

References (38)

1. Balion C, Griffith LE, Strifler L, et al. Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology 2012;79:1397-1405.
2. Annweiler C, Llewellyn DJ, Beauchet O. Low serum vitamin D concentrations in Alzheimer's disease: a systematic review and meta-analysis. J Alzheimers Dis 2013;33:659-674.
3. Annweiler C, Montero-Odasso M, Llewellyn DJ, Richard-Devantoy S, Duque G, Beauchet O. Meta-analysis of memory and executive dysfunctions in relation to vitamin D. J Alzheimers Dis 2013;37:147-171.
4. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357:266-281.
5. Thies W, Bleiler L. 2013 Alzheimer's disease facts and figures. Alzheimers Dement 2013;9:208-245.
6. Eyles DW, Smith S, Kinobe R, Hewison M, McGrath JJ. Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain. J Chem Neuroanat 2005; 29:21-30.
7. Masoumi A, Goldenson B, Ghirmai S, et al. 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. J Alzheimers Dis 2009;17:703-717.
8. Mizwicki MT, Menegaz D, Zhang J, et al. Genomic and nongenomic signaling induced by 1α,25(OH)2-vitamin D3 promotes the recovery of amyloid-b phagocytosis by Alzheimer's disease macrophages. J Alzheimers Dis 2012; 29:51-62.
9. Dursun E, Gezen-Ak D, Yilmazer S. A novel perspective for Alzheimer's disease: vitamin D receptor suppression by amyloid-b and preventing the amyloid-b induced alterations by vitamin D in cortical neurons. J Alzheimers Dis 2011;23:207-219.
10. Brøndum-Jacobsen P, Nordestgaard BG, Schnohr P, Benn M. 25-hydroxyvitamin D and symptomatic ischemic stroke: an original study and meta-analysis. Ann Neurol 2013;73:38-47.
11. Annweiler C, Montero-Odasso M, Hachinski V, Seshadri S, Bartha R, Beauchet O. Vitamin D concentration and lateral cerebral ventricle volume in older adults. Mol Nutr Food Res 2013;57:267-276.
12. Dickens AP, Lang IA, Langa KM, Kos K, Llewellyn DJ. Vitamin D, cognitive dysfunction and dementia in older adults. CNS Drugs 2011;25:629-639.
13. Llewellyn DJ, Lang IA, Langa KM, et al. Vitamin D and risk of cognitive decline in elderly persons. Arch Intern Med 2010;170:1135-1141.
14. Slinin Y, Paudel ML, Taylor BC, et al. 25-Hydroxyvitamin D levels and cognitive performance and decline in elderly men. Neurology 2010;74:33-41.
15. Slinin Y, Paudel M, Taylor BC, et al. Association between serum 25(OH) vitamin D and the risk of cognitive decline in older women. J Gerontol A Biol Sci Med Sci 2012;67: 1092-1098.
16. Annweiler C, Rolland Y, Schott AM, Blain H, Vellas B, Beauchet O. Serum vitamin D deficiency as a predictor of incident non-Alzheimer dementias: a 7-year longitudinal study. Dement Geriatr Cogn Disord 2011;32:273-278.
17. Afzal S, Bojesen SE, Nordestgaard BG. Reduced 25-hydroxyvitamin D and risk of Alzheimer's disease and vascular dementia. Alzheimers Dement 2014;10:296-302.
18. Fried LP, Borhani NO, Enright P, et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol 1991;1:263-276.
19. Kestenbaum B, Katz R, de Boer I, et al. Vitamin D, parathyroid hormone, and cardiovascular events among older adults. J Am Coll Cardiol 2011;58:1433-1441.
20. Fitzpatrick AL, Kuller LH, Ives DG, et al. Incidence and prevalence of dementia in the Cardiovascular Health Study. J Am Geriatr Soc 2004;52:195-204.
21. De Boer IH, Levin G, Robinson-Cohen C, et al. Serum 25-hydroxyvitamin D concentration and risk for major clinical disease events in a community-based population of older adults: a cohort study. Ann Intern Med 2012;156: 627-634.
22. Phinney KW. Development of a standard reference material for vitamin D in serum. Am J Clin Nutr 2008;88: 511S-512S.
23. Lopez OL, Kuller LH, Fitzpatrick A, Ives D, Becker JT, Beauchamp N. Evaluation of dementia in the cardiovascular health cognition study. Neuroepidemiology 2003; 22:1-12.
24. Radloff L. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1977;1:385-401.
25. Schoenfeld D. Partial residuals for the proportional hazards regression model. Biometrika 1982;69:239-241.
26. Llewellyn DJ, Lang IA, Langa KM, Melzer D. Vitamin D and cognitive impairment in the elderly U.S. population. J Gerontol A Biol Sci Med Sci 2011;66:59-65.
27. Brehm JM, Schuemann B, Fuhlbrigge AL, et al. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol 2010;126:52-58.e5.
28. Llewellyn D, Langa K. Serum 25-hydroxyvitamin D concentration and cognitive impairment. J Geriatr Psychiatry 2009;22:188-195.
29. Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academies Press; 2011.
30. Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011;96:1911-1930.
31. Rossom RC, Espeland MA, Manson JE, et al. Calcium and vitamin D supplementation and cognitive impairment in the women's health initiative. J Am Geriatr Soc 2012; 60:2197-2205.
32. Gezen-Ak D, Yilmazer S, Dursun E. Why vitamin D in Alzheimer's disease? the hypothesis. J Alzheimers Dis 2014;40:257-269.
33. Fernandes de Abreu DA, Eyles D, Féron F. Vitamin D, a neuro-immunomodulator: implications for neurodegenerative and autoimmune diseases. Psychoneuroendocrinology 2009;34(suppl 1):S265-S277.
34. Dursun E, Gezen-Ak D, Yilmazer S. A new mechanism for amyloid-b induction of iNOS: vitamin D-VDR pathway disruption. J Alzheimers Dis 2013;36:459-474.
35. Briones TL, Darwish H. Vitamin D mitigates age-related cognitive decline through the modulation of pro-inflammatory state and decrease in amyloid burden. J Neuroinflammation 2012;9:244.
36. Wang L, Song Y, Manson JE, et al. Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: a meta-analysis of prospective studies. Circ Cardiovasc Qual Outcomes 2012;5:819-829.
37. Buell JS, Weiner DE, Tucker L, Usda JM. 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology 2010;74:18-26.
38. Autier P, Boniol M, Pizot C, Mullie P. Vitamin D status and ill health: a systematic review. Lancet Diabetes Endocrinol 2014;2:76-89.