Developing a DNA methylation assay for human age prediction in blood and bloodstain

Forensic Science International: Genetics

Volumn 17, Issue , 2015, Pages 129-136

  Huang, Yun ^a   Yan, Jing ^a   Hou, Jiayi ^b   Fu, Xiaodan ^a   Li, Luyao ^a   Hou, Yiping ^a  

^a SICHUAN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Age prediction; DNA methylation; Forensic science; Human blood; Human bloodstain; Pyrosequencing

Indexed keywords

DNA; BIOLOGICAL MARKER;

ADULT; AGE; AGED; ARTICLE; BLOOD DONOR; BLOOD SAMPLING; BLOOD STAIN; CHILD; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION ASSAY; DNA SCREENING; FEMALE; HAN CHINESE; HUMAN; MALE; MARKER GENE; MIDDLE AGED; PREDICTION; PRIORITY JOURNAL; PYROSEQUENCING; SCHOOL CHILD; STATISTICAL MODEL; VALIDATION STUDY; ADOLESCENT; AGING; BLOOD; DNA METHYLATION; DNA SEQUENCE; FORENSIC GENETICS; GENETICS; PREDICTIVE VALUE; PROCEDURES; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGING; BIOMARKERS; BLOOD STAINS; CHILD; CPG ISLANDS; DNA; DNA METHYLATION; FEMALE; FORENSIC GENETICS; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; SEQUENCE ANALYSIS, DNA; YOUNG ADULT;

EID: 84938562001     PISSN: 18724973     EISSN: 18780326     Source Type: Journal    
DOI: 10.1016/j.fsigen.2015.05.007     Document Type: Article

References (19)

1. B.C. Christensen, E.A. Houseman, C.J. Marsit, S. Zheng, M.R. Wrench, J.L. Wiemels, H.H. Nelson, M.R. Karagas, J.F. Padbury, R. Bueno, D.J. Sugarbaker, R.F. Yeh, J.K. Wiencke, and K.T. Kelsey Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context PLoS Genet. 5 2009 e1000602
2. R.S. Alisch, B.G. Barwick, P. Chopra, L.K. Myrick, G.A. Satten, K.N. Conneely, and S.T. Warren Age-associated DNA methylation in pediatric populations Genome Res. 22 2012 623 632
3. S. Bork, S. Pfister, H. Witt, P. Horn, B. Korn, A.D. Ho, and W. Wagner DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells Aging Cell 9 2010 54 63
4. C.M. Koch, and W. Wagner Epigenetic-aging-signature to determine age in different tissues Aging (Albany NY) 3 2011 1018 1027
5. S. Bocklandt, W. Lin, M.E. Sehl, F.J. Sanchez, J.S. Sinsheimer, S. Horvath, and E. Vilain Epigenetic predictor of age PLoS One 6 2011 e14821
6. C.I. Weidner, Q. Lin, C.M. Koch, L. Eisele, F. Beier, P. Ziegler, D.O. Bauerschlag, K.H. Jöckel, R. Erbel, T.W. Mühleisen, M. Zenke, T.H. Brümmendorf, and W. Wagner Aging of blood can be tracked by DNA methylation changes at just three CpG sites Genome Biol. 2 2014 R24
7. R.Z. Piekarska, M. Spólnicka, T. Kupiec, Z. Makowska, A. Spas, A.P. Proszek, K. Kucharczyk, R. Płoski, and W. Branicki Examination of DNA methylation status of the ELOVL2 marker may be useful for human age prediction in forensic science Forensic Sci. Int. Genet. 14 2015 161 167
8. S.H. Yi, K. Mei, L.C. Xu, D.X. Huang, and R.Z. Yang Isolation and identification of age-related DNA methylation markers for forensic age-prediction Forensic Sci. Int. Genet. 11 2014 117 125
9. S.H. Yi, Y.S. Jia, K. Mei, R.Z. Yang, and D.X. Huang Age-related DNA methylation changes for forensic age-prediction Int. J. Legal Med. 2015 10.1007/s00414-014-1100-3
10. W. Wei, H.B. Luo, J. Yan, and Y.P. Hou Exploring of new Y-chromosome SNP loci using pyrosequencing and the SNaPshot methods Int. J. Legal Med. 6 2012 825 833
11. Z. Ren, H.B. Luo, F. Song, J. Zhang, H. Zhu, and Y.P. Hou Screening of mtDNA SNPs in Chinese Han population using pyrosequencing Forensic Sci. Int. Genet. 4 Supplement series 2013 e316 e317
12. E. Dejeux, H. Elabdalaoui, I.G. Gut, and J. Tost Identification and quantification of differentially methylated loci by the pyrosequencing technology Methods Mol. Biol. 507 2009 189 205
13. M.F. Fraga, and M. Esteller DNA methylation: a profile of methods and applications BioTechniques 33 2002 636 649
14. J. Tost, and I.G. Gut DNA methylation analysis by pyrosequencing Nat. Protoc. 2 9 2007 2265 2275
15. A. Schmeling, C. Grundmann, A. Fuhrmann, H.J. Kaatsch, B. Knell, F. Ramsthaler, W. Reisinger, T. Riepert, S. Ritz-Timme, F.W. Rösing, K. Rötzscher, and G. Geserick Criteria for age estimation in living individuals Int. J. Legal Med. 6 2008 457 460
16. A. Schmeling, G. Geserick, W. Reisinger, and A. Olze Age estimation Forensic Sci. Int. 165 2007 178 181
17. R.F. Thompson, G. Atzmon, C. Gheorghe, H.Q. Liang, C. Lowes, J.M. Greally, and N. Barzilai Tissue-specific dysregulation of DNA methylation in aging Aging Cell 9 2010 506 518
18. A. Choi, K.J. Shin, W.I. Yang, and H.Y. Lee Body fluid identification by integrated analysis of DNA methylation and body fluid-specific microbial DNA Int. J. Legal Med. 1 2014 33 41
19. A.E. Teschendorf, U. Menon, A. Gentry-Maharaj, S.J. Ramus, D.J. Weisenberger, H. Shen, M. Campan, H. Noushmehr, S.G. Bell, A.P. Maxwell, D.A. Savage, E. Mueller-Holzner, and C. Marth Age dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer Genome Res. 20 2010 440 446