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Volumn 43, Issue 6, 2015, Pages 569-575

Severe Lymphopenia Is Associated with Elevated Plasma Interleukin-15 Levels and Increased Mortality during Severe Sepsis

Author keywords

interleukin 15; interleukin 7; lymphopenia; outcome; Sepsis

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; MESSENGER RNA; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA;

EID: 84938528625     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000347     Document Type: Article
Times cited : (72)

References (31)
  • 1
    • 84855994257 scopus 로고    scopus 로고
    • Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern
    • Heffernan DS, Monaghan SF, Thakkar RK, Machan JT, Cioffi WG, Ayala A: Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern. Crit Care 16(1):R12, 2012.
    • (2012) Crit Care , vol.16 , Issue.1 , pp. R12
    • Heffernan, D.S.1    Monaghan, S.F.2    Thakkar, R.K.3    Machan, J.T.4    Cioffi, W.G.5    Ayala, A.6
  • 2
    • 77958534644 scopus 로고    scopus 로고
    • Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit
    • de Jager CP, van Wijk PT, Mathoera RB, de Jongh-Leuvenink J, van der Poll T, Wever PC: Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit. Crit Care 14(5):R192, 2010.
    • (2010) Crit Care , vol.14 , Issue.5 , pp. R192
    • De Jager, C.P.1    Van Wijk, P.T.2    Mathoera, R.B.3    De Jongh-Leuvenink, J.4    Van Der Poll, T.5    Wever, P.C.6
  • 4
    • 0030976184 scopus 로고    scopus 로고
    • Lymphocytopenia in a hospital populationV what does it signify?
    • Castelino DJ, McNair P, Kay TW: Lymphocytopenia in a hospital populationV what does it signify? Aust N Z J Med 27(2):170-174, 1997.
    • (1997) Aust N Z J Med , vol.27 , Issue.2 , pp. 170-174
    • Castelino, D.J.1    McNair, P.2    Kay, T.W.3
  • 12
    • 77954183132 scopus 로고    scopus 로고
    • Immunotherapy for sepsisVa new approach against an ancient foe
    • Hotchkiss RS, Opal S: Immunotherapy for sepsisVa new approach against an ancient foe. N Engl J Med 363(1):87-89, 2010.
    • (2010) N Engl J Med , vol.363 , Issue.1 , pp. 87-89
    • Hotchkiss, R.S.1    Opal, S.2
  • 13
    • 0036672918 scopus 로고    scopus 로고
    • Maintaining the norm: T-cell homeostasis
    • Jameson SC: Maintaining the norm: T-cell homeostasis. Nat Rev Immunol 2(8): 547-556, 2002.
    • (2002) Nat Rev Immunol , vol.2 , Issue.8 , pp. 547-556
    • Jameson, S.C.1
  • 17
    • 79957888573 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis: 2010
    • Cummins NW, Badley AD: Mechanisms of HIV-associated lymphocyte apoptosis: 2010. Cell Death Dis 1:e99, 2010.
    • (2010) Cell Death Dis , vol.1 , pp. e99
    • Cummins, N.W.1    Badley, A.D.2
  • 20
    • 34250890678 scopus 로고    scopus 로고
    • IL-15 is required for sustained lymphopenia-driven proliferation and accumulation of CD8 T cells
    • Sandau MM, Winstead CJ, Jameson SC: IL-15 is required for sustained lymphopenia-driven proliferation and accumulation of CD8 T cells. J Immunol 179(1):120-125, 2007.
    • (2007) J Immunol , vol.179 , Issue.1 , pp. 120-125
    • Sandau, M.M.1    Winstead, C.J.2    Jameson, S.C.3
  • 21
    • 84873339299 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup: Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2012
    • Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, et al. Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup: surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med 41(2):580-637, 2013.
    • (2013) Crit Care Med , vol.41 , Issue.2 , pp. 580-637
    • Dellinger, R.P.1    Levy, M.M.2    Rhodes, A.3    Annane, D.4    Gerlach, H.5    Opal, S.M.6    Sevransky, J.E.7    Sprung, C.L.8    Douglas, I.S.9    Jaeschke, R.10
  • 23
    • 34247235247 scopus 로고    scopus 로고
    • Acute Kidney Injury Network: Acute Kidney Injury Network: Report of an initiative to improve outcomes in acute kidney injury
    • Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A, Acute Kidney Injury Network: Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 11(2):R31, 2007.
    • (2007) Crit Care , vol.11 , Issue.2 , pp. R31
    • Mehta, R.L.1    Kellum, J.A.2    Shah, S.V.3    Molitoris, B.A.4    Ronco, C.5    Warnock, D.G.6    Levin, A.7
  • 24
    • 84871774938 scopus 로고    scopus 로고
    • version 4.0
    • National Cancer Institute: common terminology criteria for adverse events (CTCAE), version 4.0.Available at: (http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE- 4.03-2010-06-14-QuickReference-8.5x11.pdf)
    • Common Terminology Criteria for Adverse Events (CTCAE)
  • 25
    • 0141542480 scopus 로고    scopus 로고
    • Real-time reverse transcription-PCR assay for future management of ERBB2- based clinical applications
    • Bieche I, Onody P, Laurendeau I, Olivi M, Vidaud D, Lidereau R, Vidaud M: Real-time reverse transcription-PCR assay for future management of ERBB2- based clinical applications. Clin Chem 45(8):1148-1156, 1999.
    • (1999) Clin Chem , vol.45 , Issue.8 , pp. 1148-1156
    • Bieche, I.1    Onody, P.2    Laurendeau, I.3    Olivi, M.4    Vidaud, D.5    Lidereau, R.6    Vidaud, M.7
  • 31
    • 17044413706 scopus 로고    scopus 로고
    • Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways
    • Hotchkiss RS, Osmon SB, Chang KC, Wagner TH, Coopersmith CM, Karl IE: Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways. J Immunol 174(8):5110-5118, 2005.
    • (2005) J Immunol , vol.174 , Issue.8 , pp. 5110-5118
    • Hotchkiss, R.S.1    Osmon, S.B.2    Chang, K.C.3    Wagner, T.H.4    Coopersmith, C.M.5    Karl, I.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.