Sepsis-induced hypercytokinemia and lymphocyte apoptosis in aging-accelerated Klotho knockout mice

Shock

Volumn 39, Issue 3, 2013, Pages 311-316

  Inoue, Shigeaki ^a   Sato, Takehito ^a   Suzuki Utsunomiya, Kyoko ^a   Komori, Yukako ^a   Hozumi, Katsuto ^a   Chiba, Tomoki ^a   Yahata, Takashi ^a   Nakai, Kozo ^b   Inokuchi, Sadaki ^a  

^a TOKAI UNIVERSITY   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

Author keywords

Aging; hypercytokinemia; immunosuppression; Klotho; lymphocyte; sepsis

Indexed keywords

CASPASE 3; INTERLEUKIN 10; INTERLEUKIN 6; KLOTHO PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL CLEARANCE; BACTERIUM COLONY; CECUM; CONTROLLED STUDY; CYTOKINE STORM; FEMALE; FLOW CYTOMETRY; GENE INACTIVATION; IMMUNOHISTOLOGY; INTESTINE SURGERY; LYMPHOCYTE; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PERITONEAL CAVITY; PERITONEUM LAVAGE; SEPSIS; SPLEEN; SURVIVAL; THYMUS;

AGING, PREMATURE; ANIMALS; APOPTOSIS; BACTERIAL LOAD; COLONY COUNT, MICROBIAL; CYTOKINES; FEMALE; GLUCURONIDASE; IMMUNITY, INNATE; LYMPHOCYTE COUNT; LYMPHOCYTES; MICE; MICE, KNOCKOUT; PERITONEAL CAVITY; SEPSIS; SPLEEN; SURVIVAL ANALYSIS; THYMUS GLAND;

EID: 84874260721     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3182845445     Document Type: Article

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