Influx of extracellular Zn2+ into the hippocampal CA1 neurons is required for cognitive performance via long-term potentiation

Neuroscience

Volumn 304, Issue , 2015, Pages 209-216

  Takeda, A ^a   Suzuki, M ^a   Tempaku, M ^a   Ohashi, K ^a   Tamano, H ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

CA1 pyramidal cell; Cognition; Hippocampus; LTP; Schaffer collateral; Zn2+ signaling

Indexed keywords

CHELATING AGENT; EDETATE CALCIUM; ZINC CHLORIDE; ZINC ION; CATION; CHLORIDE; PSYCHOTROPIC AGENT; ZINC; ZINC DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL CEREBROSPINAL FLUID; CATION TRANSPORT; CELL LEVEL; CEREBROSPINAL FLUID; CHELATION; COGNITION; DRUG EFFECT; ELECTRODE; HIPPOCAMPAL CA1 REGION; IN VIVO STUDY; LEARNING; LONG TERM POTENTIATION; MALE; MENTAL PERFORMANCE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RECOGNITION; SIGNAL TRANSDUCTION; ZINC CELL LEVEL; ZINC TRANSPORT; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; EXCITATORY POSTSYNAPTIC POTENTIAL; EXTRACELLULAR SPACE; MEMORY DISORDER; METABOLISM; MICROELECTRODE; NERVE CELL; NEUROPSYCHOLOGICAL TEST; PHYSIOLOGY; WISTAR RAT;

ANIMALS; CA1 REGION, HIPPOCAMPAL; CATIONS; CHELATING AGENTS; CHLORIDES; COGNITION; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; EXTRACELLULAR SPACE; LONG-TERM POTENTIATION; MALE; MEMORY DISORDERS; MICRODIALYSIS; MICROELECTRODES; NEURONS; NEUROPSYCHOLOGICAL TESTS; PSYCHOTROPIC DRUGS; RATS, WISTAR; RECOGNITION (PSYCHOLOGY); ZINC; ZINC COMPOUNDS;

EID: 84938524122     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.07.042     Document Type: Article

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