Gold-Catalyzed Cyclization Leads to a Bridged Tetracyclic Indolenine that Represses β-Lactam Resistance

Angewandte Chemie - International Edition

Volumn 54, Issue 33, 2015, Pages 9546-9549

  Xu, Wenqing ^a   Wang, Wei ^a   Wang, Xiang ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

antibiotics; drug discovery; gold; heterocycles; synthetic methods

Indexed keywords

ACTIVATION ANALYSIS; ANTIBIOTICS; CATALYSIS; GOLD;

BETA-LACTAMS; CYCLIZATION PRODUCTS; DRUG DISCOVERY; FACILE SYNTHESIS; HETEROCYCLES; INDOLE ALKALOIDS; METHICILLIN; SYNTHETIC METHODS;

CYCLIZATION;

ANTIINFECTIVE AGENT; BETA LACTAM; GOLD; INDOLE DERIVATIVE;

ANTIBIOTIC RESISTANCE; CHEMISTRY; CYCLIZATION; DRUG DESIGN; DRUG EFFECTS; DRUG POTENTIATION; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TEST; STAPHYLOCOCCAL INFECTIONS; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; BETA-LACTAMS; CYCLIZATION; DRUG DESIGN; DRUG SYNERGISM; GOLD; HUMANS; INDOLES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCAL INFECTIONS;

EID: 84938408274     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201503736     Document Type: Article

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